Search results for "SHO"

showing 10 items of 5071 documents

Cellular and humoral immunity to the 60-kD heat shock protein in inflammatory bowel disease.

1997

Background: Mycobacteria have been considered a possible etiological agent in Crohn’s disease. Since cross-reactivity between epitopes of mycobacterial and self-heat shock protein might represent a potential disease mechanism, we determined the cellular and humoral immune responses to the mycobacterial and the human 60-kD heat shock protein, as well as various control antigens. Methods: We studied samples from 19 patients with Crohn’s disease, 12 patients with ulcerative colitis, and from 19 healthy individuals. T cell responses were studied using a standard proliferation assays to purified recombinant mycobacterial and human 60-kD heat shock protein. Antibody levels were measured by establ…

AdultCellular immunityEnzyme-Linked Immunosorbent AssayBiologymedicine.disease_causeLymphocyte ActivationInflammatory bowel diseaseMicrobiologyAutoimmunityImmune systemAntigenCrohn DiseaseHeat shock proteinmedicineHumansLymphocytesAntigens BacterialGastroenterologyChaperonin 60Mycobacterium tuberculosismedicine.diseaseShock (circulatory)Case-Control StudiesHumoral immunityImmunologyAntibody FormationColitis Ulcerativemedicine.symptomDigestion
researchProduct

Acute effects on the human EEG after an external exposure to 200 ppm methanol

2001

Objectives: Even low concentrations of organic solvents may cause acute effects on the human central nervous system. The German MAK (threshold limit value) of methanol is 200 ppm. The aim of this study was to investigate whether acute exposure to 200 ppm methanol causes adverse effects, measured by EEG, and moreover, whether it is possible to differentiate between sedative and excitatory effects with this method. Methods: Twelve healthy subjects were exposed for 4 h to 200 ppm and to 20 ppm (control) in an exposure chamber in a cross-over design. The EEG was recorded before (reference) and at the end of each exposure with, the subject's eyes closed and opened and during a choice reaction te…

AdultCentral Nervous SystemMaleAcute effectsmedicine.drug_classThreshold limit valueElectroencephalographychemistry.chemical_compoundReference ValuesHumansMedicineSingle-Blind MethodThreshold Limit ValuesInhalation ExposureCross-Over Studiesmedicine.diagnostic_testInhalationbusiness.industryMethanolPublic Health Environmental and Occupational HealthElectroencephalographychemistrySedativeAnesthesiaToxicityExposure chamberMethanolbusinessInternational Archives of Occupational and Environmental Health
researchProduct

Similar planning strategies for whole-body and arm movements performed in the sagittal plane

2003

The present paper looks for kinematic similarities between whole-body and arm movements executed in the sagittal plane. Eight subjects performed sit-to-stand (STS) and back-to-sit (BTS) movements at their preferred speed in the sagittal plane. Kinematics analysis focused on shoulder motion revealed that STS was composed of a straight, forward displacement followed by a curved, upward displacement while BTS was characterized by a curved, downward and straight, backward displacement. Curvature of the upward displacement was significantly greater than the downward one. Analysis of shoulder-velocity profiles showed that movement duration was significantly longer for BTS compared with STS and th…

AdultCentral Nervous SystemMaleShoulder JointMovement (music)MovementGeneral NeuroscienceBody movementKinematicsGeodesyCurvatureDisplacement (vector)Sagittal planeBiomechanical PhenomenaAccelerationmedicine.anatomical_structureArmmedicineHumansWhole bodyPsychomotor PerformanceGeologyNeuroscience
researchProduct

Mechanical–biological waste treatment and the associated occupational hygiene in Finland

2004

A special feature of waste management in Finland has been the emphasis on the source separation of kitchen biowaste (catering waste); more than two-thirds of the Finnish population participates in this separation. Source-separated biowaste is usually treated by composting. The biowaste of about 5% of the population is handled by mechanical-biological treatment. A waste treatment plant at Mustasaari is the only plant in Finland using digestion for kitchen biowaste. For the protection of their employees, the plant owners commissioned a study on environmental factors and occupational hygiene in the plant area. During 1998-2000 the concentrations of dust, microbes and endotoxins and noise level…

AdultEngineeringbusiness.product_categoryThreshold limit valuePopulationAir MicrobiologyAir Pollutants OccupationalOccupational safety and healthWaste ManagementOccupational hygieneOccupational ExposureBiological wasteHumansRespiratoreducationWaste Management and DisposalFinlandOccupational Healtheducation.field_of_studyWaste managementbusiness.industryDry coughTemperatureDustHumidityEndotoxinsWaste treatmentNoise OccupationalbusinessWaste Management
researchProduct

Soccer players' fitting perception of different upper boot materials.

2016

[EN] The present study assessed the influence of upper boot materials on fitting perception. Twenty players tested three soccer boots only differing in the upper boot material (natural calf leather, natural kangaroo leather and synthetic leather). Players reported fitting perception and preference on specific foot areas using a perceived fitting scale. Ratings were averaged for every foot area. Repeated measures ANOVA was used to analyze the differences between boots. The kangaroo leather boots were perceived tighter and closer to the preferred fitting in general fitting, metatarsals area and instep area. The synthetic leather boots were perceived as the loosest and as the most distant boot…

AdultEngineeringmedia_common.quotation_subjectFootballPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsUpperFootwear03 medical and health sciencesYoung Adult0302 clinical medicinePerceptionStatisticsSoccerAnimalsHumans0501 psychology and cognitive sciencesOperations managementSafety Risk Reliability and QualityEngineering (miscellaneous)050107 human factorsmedia_commonMacropodidaeAnalysis of Variancebusiness.industry05 social sciences030229 sport sciencesEquipment DesignConsumer BehaviorComfortShoesLeatherLeather bootsCattlePerceptionFittingbusinessApplied ergonomics
researchProduct

Efficacy of Focused Extracorporeal Shock Wave Therapy in Chronic Low Back Pain: A Prospective Randomized 3-Month Follow-Up Study.

2022

BACKGROUND Extracorporeal shock wave therapy (ESWT) is a modern physiotherapeutic method that is useful for treating musculoskeletal conditions. There are still limited data from well-designed studies evaluating the clinical efficiency of ESWT in low back pain (LBP). Therefore, this study aimed to assess the effectiveness of the focused ESWT (fESWT) in reducing pain and improving the functional status of patients with chronic LBP. MATERIAL AND METHODS The study involved 40 patients with L5-S1 discopathy with chronic LBP pain who were randomized into 2 groups: group A (n=20, mean age of 42.3±13.1 years) and group B (n=20, mean age of 45.4±14 years). Group A was an experimental group treated …

AdultExtracorporeal Shockwave TherapyLipopolysaccharidesGeneral MedicineMiddle Agedfunctional statusTreatment OutcomeRandomized controlled trialHumansProspective Studieschronic painLow Back PainPhysical Therapy ModalitiesFollow-Up StudiesMedical science monitor : international medical journal of experimental and clinical research
researchProduct

The Effectiveness Of Radial Extracorporeal Shock Wave Therapy In Patients With Chronic Low Back Pain: A Prospective, Randomized, Single-Blinded Pilot…

2019

Karolina Walewicz,1 Jakub Taradaj,2,3 Katarzyna Rajfur,1 Kuba Ptaszkowski,4 Michał Tomasz Kuszewski,2 Mirosław Sopel,5 Robert Dymarek5 1Faculty of Physiotherapy, Opole Medical School, Opole, Poland; 2Institute of Physiotherapy and Health Sciences, Academy of Physical Education, Katowice, Poland; 3College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada; 4Department of Physiotherapy, Wroclaw Medical University, Wroclaw, Poland; 5Department of Nervous System Diseases, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Robert DymarekDepartment of Nervous System Diseases, Faculty of Health Sciences, Wroclaw Medical University, Bartla 5, Wroclaw 51-618, PolandTe…

AdultExtracorporeal Shockwave TherapyMaleExtracorporeal shock wave therapyVisual analogue scalePilot Projects03 medical and health sciences0302 clinical medicineHumansPain ManagementMedicinephysical therapySingle-Blind MethodIn patientProspective Studies030212 general & internal medicineOriginal ResearchPain Measurementfunctional statebusiness.industryESWTshock wavesGeneral MedicinePain scaleMiddle AgedLow back painChronic low back painOswestry Disability IndexTreatment OutcomeAnesthesiaClinical Interventions in AgingHomogeneous groupFemaleGeriatrics and Gerontologymedicine.symptombusinessLow Back Pain030217 neurology & neurosurgeryClinical Interventions in Aging
researchProduct

Kardiale MRT : Änderungen der normalisierten myokardialen Gadolinium-Anreicherung über die Zeit nach Kontrastmittelinjektion in Patienten mit akuter …

2011

PURPOSE An increased normalized gadolinium accumulation (NGA) in the myocardium during early washout has been used for the diagnosis of acute myocarditis (AM). Due to the fact that the pharmacokinetics of contrast agents are complex, time-related changes in NGA after contrast injection are likely. Because knowledge about time-related changes of NGA may improve the diagnostic accuracy of MR, our study aimed to estimate the time course of NGA after contrast injection in patients as well as in healthy volunteers. MATERIALS AND METHODS An ECG-triggered inversion recovery SSFP sequence with incrementally increasing inversion times was repetitively acquired over the 15 minutes after injection of …

AdultGadolinium DTPAMalemedicine.medical_specialtymedia_common.quotation_subjectGadoliniumCardiac-Gated Imaging TechniquesMedizinchemistry.chemical_elementContrast MediaSensitivity and SpecificityPharmacokineticsReference ValuesInternal medicineHealthy volunteersmedicineImage Processing Computer-AssistedContrast (vision)HumansRadiology Nuclear Medicine and imagingIn patientMuscle Skeletalmedia_commonbusiness.industryMyocardiumWashoutSteady-state free precession imagingMiddle AgedImage EnhancementMagnetic Resonance ImagingMyocardial ContractionMyocarditischemistryContrast injectionAcute DiseaseInjections IntravenousCardiologyFemalebusiness
researchProduct

Phenotypic analysis of individuals with Costello syndrome due to HRAS p.G13C.

2011

Costello syndrome is characterized by severe failure-to-thrive, short stature, cardiac abnormalities (heart defects, tachyarrhythmia, and hypertrophic cardiomyopathy (HCM)), distinctive facial features, a predisposition to papillomata and malignant tumors, postnatal cerebellar overgrowth resulting in Chiari 1 malformation, and cognitive disabilities. De novo germline mutations in the proto-oncogene HRAS cause Costello syndrome. Most mutations affect the glycine residues in position 12 or 13, and more than 80% of patients share p.G12S. To test the hypothesis that subtle genotype-phenotype differences exist, we report the first cohort comparison between 12 Costello syndrome individuals with p…

AdultHeart Defects CongenitalMalemedicine.medical_specialtyAdolescentrasopathy.RASopathyShort statureProto-Oncogene MasArticleProto-Oncogene Proteins p21(ras)Young AdultGermline mutationSettore MED/38 - Pediatria Generale E SpecialisticaCostello syndromePregnancyInternal medicineNeoplasmsGeneticsMedicineHumansHRASChildGenetics (clinical)business.industryloose anagen hairCostello SyndromeMacrocephalyHypertrophic cardiomyopathyBrainInfantgenotype–phenotype correlationmedicine.diseaseDermatologyMagnetic Resonance ImagingMusculoskeletal AbnormalitiesEndocrinologyPhenotypeChild PreschoolFaceMutationFemalemedicine.symptombusinessMultifocal atrial tachycardiaAmerican journal of medical genetics. Part A
researchProduct

Search for a gene responsible for Floating-Harbor syndrome on chromosome 12q15q21.1.

2012

International audience; Floating-Harbor syndrome (FHS) is characterized by characteristic facial dysmorphism, short stature with delayed bone age, and expressive language delay. To date, the gene(s) responsible for FHS is (are) unknown and the diagnosis is only made on the basis of the clinical phenotype. The majority of cases appeared to be sporadic but rare cases following autosomal dominant inheritance have been reported. We identified a 4.7 Mb de novo 12q15-q21.1 microdeletion in a patient with FHS and intellectual deficiency. Pangenomic 244K array-CGH performed in a series of 12 patients with FHS failed to identify overlapping deletions. We hypothesized that FHS is caused by haploinsuf…

AdultHeart Septal Defects VentricularMaleCandidate geneFloating Harbor syndrome[SDV.GEN] Life Sciences [q-bio]/GeneticsHaploinsufficiencyBiologyBioinformaticsShort statureCraniofacial Abnormalities03 medical and health sciences12q15q21.1 microdeletion[SDV.BDD] Life Sciences [q-bio]/Development BiologyGeneticsmedicineHumansAbnormalities MultipleGenetic Predisposition to Disease[ SDV.BDD ] Life Sciences [q-bio]/Development BiologyChild[SDV.BDD]Life Sciences [q-bio]/Development BiologyGenetics (clinical)Growth Disorders030304 developmental biologySequence DeletionPhenocopyGenetics0303 health sciencesComparative Genomic Hybridization[SDV.GEN]Life Sciences [q-bio]/GeneticsChromosomes Human Pair 12Genetic heterogeneity030305 genetics & heredityChromosomeHigh-Throughput Nucleotide Sequencinghigh-throughput sequencingmedicine.disease3. Good healthPhenotypeFloating–Harbor syndromeChild PreschoolMutation (genetic algorithm)Femalemedicine.symptomHaploinsufficiency[ SDV.GEN ] Life Sciences [q-bio]/Genetics
researchProduct