Search results for "SHO"
showing 10 items of 5071 documents
PSA and PSA Kinetics Thresholds for the Presence of 68Ga-PSMA-11 PET/CT-Detectable Lesions in Patients with Biochemical Recurrent Prostate Cancer
2020
68Ga-PSMA-11 positron-emission tomography/computed tomography (PET/CT) is commonly used for restaging recurrent prostate cancer (PC) in European clinical practice. The goal of this study is to determine the optimum time for performing these PET/CT scans in a large cohort of patients by identifying the prostate-specific-antigen (PSA) and PSA kinetics thresholds for detecting and localizing recurrent PC. This retrospective analysis includes 581 patients with biochemical recurrence (BC) by definition. The performance of 68Ga-PSMA-11 PET/CT in relation to the PSA value at the scan time as well as PSA kinetics was assessed by the receiver-operating-characteristic-curve (ROC) generated by plottin…
The small heat-shock protein α B-crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis
2014
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by the proliferation of myofibroblasts and the accumulation of extracellular matrix (ECM) in the lungs. TGF-β1 is the major profibrotic cytokine involved in IPF and is responsible for myofibroblast proliferation and differentiation and ECM synthesis. αB-crystallin is constitutively expressed in the lungs and is inducible by stress, acts as a chaperone and is known to play a role in cell cytoskeleton architecture homeostasis. The role of αB-crystallin in fibrogenesis remains unknown. The principal signalling pathway involved in this process is the Smad-dependent pathway. We demonstrate here that αB-crystallin is stron…
Electric and elastic properties of conductive polymeric nanocomposites on macro- and nanoscales
2002
Abstract In the past several years, the macroscopic electric and elastic properties of conductive polymeric composites have been studied from the viewpoint of such applications as thermistors and pressure sensors. In particular, we studied carbon black (CB) polymeric nanocomposites on macro- and nanoscales, using polyisoprene as the composite matrix. The filler component was an extra conductive carbon black (PRINTEX XE2, DEGUSSA) with a primary particle diameter of about 30 nm. A very strong reversible tensoresistive effect of electric resistance dependence on uniaxial tension deformation was observed in composites with the 10 carbon black mass parts added to 100 mass parts of polyisoprene.…
Specific and global regulation of mRNA stability during osmotic stress in Saccharomyces cerevisiae.
2009
Hyperosmotic stress yields reprogramming of gene expression in Saccharomyces cerevisiae cells. Most of this response is orchestrated by Hog1, a stress-activated, mitogen-activated protein kinase (MAPK) homologous to human p38. We investigated, on a genomic scale, the contribution of changes in transcription rates and mRNA stabilities to the modulation of mRNA amounts during the response to osmotic stress in wild-type and hog1 mutant cells. Mild osmotic shock induces a broad mRNA destabilization; however, osmo-mRNAs are up-regulated by increasing both transcription rates and mRNA half-lives. In contrast, mild or severe osmotic stress in hog1 mutants, or severe osmotic stress in wild-type cel…
On the modelling of an Acid/Base Flow battery: an innovative electrical energy storage device based on pH and salinity gradients
2019
The Acid/Base Flow Battery (AB-FB) is an innovative and sustainable way to store electric energy. It can theoretically guarantee an energy density of about 11 kWh/m3, which is higher than that provided by pumped hydropower, osmotic energy storage and compressed air. The AB-FB stores energy as pH and salinity gradients by employing a stack provided with (i) channels, hosting the solutions at difference pH and concentrations, separated by (ii) monopolar and bipolar ion exchange membranes. Two different membrane processes are involved: the Bipolar Membrane Electrodialysis (ED-BM) as charging step and its opposite, Bipolar Membrane Reverse Electrodialysis (RED-BM) as discharging step. The prese…
Vers le contrôle de l'alignement et de l'orientation : théorie et expérience
2010
This thesis is about the control and characterisation of the alignment and orientation of molecules by ultra short laser pulses on a theoretical and experimental approach. Alignment corresponds to a symmetric angular distribution of the molecular axis peaked along the laser field axis, whereas orientation provides an asymmetric distribution favouring one spatial direction. Orientation by sudden two-colour (2+1) pulses is studied extensively for the non resonant case and conditions required for achieving significant orientation are explored. A second two-colour scheme, where the second harmonic is in quasi resonance with a vibrational level of the molecule, is also presented and discussed. T…
Spuścizna pisarska biskupa Franciszka Jopa (1897-1976)
2016
Obchodzona w 2016 r. 40. rocznica śmierci bpa Franciszka Jopa skłoniła środowisko historyków Kościoła oraz duchowieństwo i wiernych Śląska Opolskiego do licznych inicjatyw, mających na celu upamiętnienie pierwszego biskupa opolskiego. Niniejszy tekst poświęcony jest spuściźnie pisarskiej bpa Jopa. Autor, przy pomocy wcześniejszych opracowań, wskazuje na spis 357 pozycji pisarskich pasterza, jakie zamieszczono w 1978 r. w „Studiach Teologiczno-Historycznych Śląska Opolskiego”. Spis ów uzupełnia o 6 kolejnych tekstów, będącymi przemówieniami i pisemnymi opiniami pasterza, jakie wygłosił lub przesłał na piśmie w czasie Soboru Watykańskiego II, a które wydrukowane zostały w Acta Synodalia sacro…
LA CHIESA NELLO STATO
2010
The essay outlines the relationship between State and Church from Constantine to Theodosius I, through the various emperors who succeeded to the throne. Particular attention is paid to the granting of legal personality to the Church, the figure of the bishop and the episcopalis audientia.
On the Bishop-Phelps-Bollobás type theorems
2017
This dissertation is devoted to the study of the Bishop-Phelps-Bollobás property in different contexts. In Chapter 1 we give a historical resume and the motivation behind this property as the classics Bishop-Phelps and Bishop-Phelps-Bollobás theorems. We define the Bishop-Phelps-Bollobás property (BPBp) and we comment on some important current results. In Chapter 2 we study similar properties to the BPBp. First, we define the Bishop-Phelps-Bollobás point property (BPBpp). The BPBpp is stronger than the BPBp. We study it for bounded linear operators and then for bilinear mappings. After that, we study two more similar properties: properties 1 and 2. Property 2 is just the dual property of th…
The Bishop–Phelps–Bollobás theorem for L(L1(μ),L∞[0,1])
AbstractWe show that the Bishop–Phelps–Bollobás theorem holds for all bounded operators from L1(μ) into L∞[0,1], where μ is a σ-finite measure.