Search results for "SHORT-TERM"
showing 10 items of 240 documents
Single neuron binding properties and the magical number 7
2008
When we observe a scene, we can almost instantly recognize a familiar object or can quickly distinguish among objects differing by apparently minor details. Individual neurons in the medial temporal lobe of humans have been shown to be crucial for the recognition process, and they are selectively activated by different views of known individuals or objects. However, how single neurons could implement such a sparse and explicit code is unknown and almost impossible to investigate experimentally. Hippocampal CA1 pyramidal neurons could be instrumental in this process. Here, in an extensive series of simulations with realistic morphologies and active properties, we demonstrate how n radial (ob…
The self-organizing consciousness
2003
We propose that the isomorphism generally observed between the representations composing our momentary phenomenal experience and the structure of the world is the end-product of a progressive organization that emerges thanks to elementary associative processes that take our conscious representations themselves as the stuff on which they operate, a thesis that we summarize in the concept of Self-Organizing Consciousness (SOC).
Auditory discrimination profiles of speech sound changes in 6-year-old children as determined with the multi-feature MMN paradigm.
2009
Objective: A linguistic multi-feature mismatch negativity (MMN) paradigm with five types of changes (vowel, vowel-duration, consonant, frequency (F0), and intensity) in Finnish syllables was used to determine speech-sound discrimination in 17 normally-developing 6-year-old children. The MMNs for vowel and vowel-duration were also recorded in an oddball condition in order to compare the two paradigms. Similar MMNs in the two paradigms would suggest that they tap the same processes. This would promote the usefulness of the more time-efficient multi-feature paradigm for future studies in children. Methods: MMNs to five deviant types were recorded in the multi-feature paradigm in which these de…
Dimensions of executive functioning: Evidence from children
2003
This study investigated dimensions of executive functioning in 8- to 13-year-old children. Three tasks from the Cambridge Neuropsychological Test Automated Battery (CANTAB), two tasks from the NEPSY battery and some additional executive function (EF) tests were administered to 108 children. In line with earlier work, modest correlations among EF measures were obtained (r < .4). Both exploratory and confirmatory factor analyses yielded three interrelated factors, which resembled those obtained by Miyake et al. (2000) and which were—with some reservations—labelled Working Memory (WM), Inhibition and Shifting. Age correlated with performance on most individual EF measures as well as Shifting a…
Domestic Violence Interventions in Social and Health Care Settings: Challenges of Temporary Projects and Short-Term Solutions.
2020
Social welfare service and health care providers are in a key position to implement successful domestic violence (DV) interventions. However, it is known that DV intervention and prevention work is often lacking in coordination and continuity. In addition, the limited resources, hectic work pace, and changing practices negatively affect the development of successful ways to prevent and intervene in DV. This qualitative study involving 11 focus groups, composed of social welfare and health care professionals ( n = 51) in a midsized Finnish hospital, examined the challenges and possibilities within DV interventions and the adoption of good practices produced by a DV intervention development …
Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and…
2009
Neurogenesis in the adult dentate gyrus (DG) of the hippocampus has been implicated in neural plasticity and cognition but the specific functions contributed by adult-born neurons remain controversial. Here, we have explored the relationship between adult hippocampal neurogenesis and memory function using tasks which specifically require the participation of the DG. In two separate experiments several groups of rats were exposed to fractionated ionizing radiation (two sessions of 7 Gy each on consecutive days) applied either to the whole brain or focally, aiming at a region overlying the hippocampus. The immunocytochemical assays showed that the radiation significantly reduced the expressio…
Measuring psychosocial stress with heart rate variability-based methods in different health and age groups
2022
Abstract Objective. Autonomic nervous system function and thereby bodily stress and recovery reactions may be assessed by wearable devices measuring heart rate (HR) and its variability (HRV). So far, the validity of HRV-based stress assessments has been mainly studied in healthy populations. In this study, we determined how psychosocial stress affects physiological and psychological stress responses in both young (18–30 years) and middle-aged (45–64 years) healthy individuals as well as in patients with arterial hypertension and/or either prior evidence of prediabetes or type 2 diabetes. We also studied how an HRV-based stress index (Relax-Stress Intensity, RSI) relates to perceived stress …
Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients
2015
Background: Magnetic Resonance Imaging (MRI) techniques provided evidences into the understanding of cognitive impairment (CIm) in Multiple Sclerosis (MS). Objectives: To investigate the role of white matter (WM) and gray matter (GM) in predicting long-term CIm in a cohort of MS patients. Methods: 303 out of 597 patients participating in a previous multicenter clinical-MRI study were enrolled (49.4% were lost at follow-up). The following MRI parameters, expressed as fraction (f) of intracranial volume, were evaluated: cerebrospinal fluid (CSF-f), WM-f, GM-f and abnormal WM (AWM-f), a measure of lesion load. Nine years later, cognitive status was assessed in 241 patients using the Symbol Dig…
Early handling effect on female rat spatial and non-spatial learning and memory
2014
This study aims at providing an insight into early handling procedures on learning and memory performance in adult female rats. Early handling procedures were started on post-natal day 2 until 21, and consisted in 15 min, daily separations of the dams from their litters. Assessment of declarative memory was carried out in the novel-object recognition task; spatial learning, reference- and working memory were evaluated in the Morris water maze (MWM). Our results indicate that early handling induced an enhancement in: (1) declarative memory, in the object recognition task, both at 1h and 24h intervals; (2) reference memory in the probe test and working memory and behavioral flexibility in the…
Empirical evidence for musical syntax processing? Computer simulations reveal the contribution of auditory short-term memory
2014
During the last decade, it has been argued that (1) music processing involves syntactic representations similar to those observed in language, and (2) that music and language share similar syntactic-like processes and neural resources. This claim is important for understanding the origin of music and language abilities and, furthermore, it has clinical implications. The Western musical system, however, is rooted in psychoacoustic properties of sound, and this is not the case for linguistic syntax. Accordingly, musical syntax processing could be parsimoniously understood as an emergent property of auditory memory rather than a property of abstract processing similar to linguistic processing.…