Search results for "SID"
showing 10 items of 6756 documents
Mortality Risk Assessment at the Admission in Patient With Proximal Femur Fractures: Electrolytes and Renal Function
2021
In patients over 65y.o. who were surgically treated for a hip fracture, electrolytes have not been specifically studied as predictors of mortality. The main purpose of this study was to assess whether electrolytes and chronic kidney disease (CKD) stages, evaluated at admission, could represent a pre-operative prognostic factor in this population. Moreover, the role of epidemiological and clinical parameters was analyzed with and without a surgical timing stratification. This retrospective study included 746 patients. For each patient, their age, gender, fracture classification, Hb value, comorbidities, ASA class, chronic kidney disease, creatinine levels, electrolytes and surgical timing w…
A T2* MRI Prospective Survey on Heart and Liver Iron In Thalassemia Major Patients Treated with Deferasirox Versus Deferiprone and Desferrioxamine In…
2010
Abstract Abstract 4267 Introduction: Most deaths in thalassemia major (TM) result from cardiac complications due to iron overload. In thalassaemia available three iron chelation regimes in monotherapy may achieve different changes in cardiac iron and function and liver iron. No data are available in literature about prospective comparisons on cardiac iron and function and liver iron in TM patients treated with deferasirox (DFX) versus deferiprone (DFP) and desferrioxamine (DFO) in monotherapy. Magnetic Resonance (MR) is the unique non invasive suitable technique to evaluated quantitatively this issue. The aim of this multi-centre study was to assess prospectively in the clinical practice th…
Successful Control of Hypoglycemia with Pasireotide LAR in a Patient with Inappropriate Insulin Secretion
2021
Introduction Inappropriate insulin secretion could be due to several diseases. Nesidioblastosis is characterized by diffuse hyperplasia of pancreatic beta cells, causing organic hypoglycemia. No pancreatic lesions are found on the imaging of patients with this condition. Diazoxide is used as a first-line treatment but can be poorly tolerated because of its side effects, and therapeutic failure is possible. Somatostatin analogues have limited efficacy because of their poor affinity to somatostatin (SST) receptors. Pasireotide is a somatostatin analogue with a much higher affinity to SST receptors, especially SST5, and it could thus be more efficient for treating nesidioblastosis-related hypo…
Exposure to ototoxic agents and hearing loss: A review of current knowledge
2014
Several experimental and clinical studies have shown that a variety of ototoxic agents (such as drugs, industrial chemicals and noise) can cause sensorineural hearing loss. The most common ototoxic drugs used in clinical practice include: aminoglycoside and macrolide antibiotics, quinoline anti-malarials, platinum analog antineoplastics, loop diuretics, and acetylsalicylic acid. Among chemical agents with potential ototoxic properties are: organic solvents, heavy metals, organotins, nitriles, asphyxiants, and pesticides/herbicides. Acoustic exposure to high intensity and/or prolonged noise can also cause permanent threshold shifts in auditory perception. Ototoxic agents can influence audito…
An unusual association of left‐sided gastroschisis and persistent right umbilical vein
2018
Key Clinical Message Gastroschisis is a full‐thickness congenital abdominal wall defect usually occurring to the right of the umbilicus. About twenty cases of left‐sided gastroschisis have been reported, without reference to the laterality of the umbilical vein. This first case highlights the importance of considering and reporting this association by the perinatal team.
Comparison of adjuvant and adjuvant-free murine experimental asthma models
2009
Introduction The most widely used protocol for the induction of experimental allergic airway inflammation in mice involves sensitization by intraperitoneal (i.p.) injections of the antigen ovalbumin (OVA) used in conjunction with the adjuvant aluminium hydroxide (alum). Although adjuvants are frequently used, there are questions regarding the necessity of alum for murine asthma studies due to the non-physiological nature of this chemical. Objective The objective of this study was to compare experimental asthma phenotypes between adjuvant and adjuvant-free protocols of murine allergic airway inflammation in an attempt to develop a standardized alternative to adjuvant use. Method An adjuvant-…
Induction of Type-Specific Neutralizing Antibodies by Capsomeres of Human Papillomavirus Type 33
2001
Abstract The immunogenicity of capsomeres of human papillomavirus type 33 was evaluated in a dose–response analysis. Capsomeres were obtained free of capsids by expression of L1 carrying the single point mutation C427S. Neutralizing antibodies were detected using an in vitro pseudoinfection assay. Capsomeres induced type-specific, neutralizing antibodies in mice even in the absence of adjuvant. The neutralization titers of immune sera raised without adjuvant were 10- to 20-fold lower than those of antisera to virus-like particles, but virtually identical using Freund's adjuvant. These data indicate that capsomeres may substitute for virus-like particles in future vaccines when used with an …
Joies botàniques de la Ribera i voltants
2021
Catàleg de l'exposició titulada “Joies Botániques de la Ribera i voltants” que inclou fotografies de les obres exposades juntament amb explicacions detallades de cadascuna d'elles, així com una breu descripció de les tècniques emprades. S'incorporen textos i comentaris artístics i científics de diversos experts. Es tracta d'una iniciativa patrocinada per la Mancomunitat de la Ribera del Xúquer i la Universitat de València que busca sensibilitzar a la societat en temes relacionats amb la conservació de la biodiversitat i el medi ambient. Catalog of the exhibition entitled "Joies Botániques de la Ribera i voltants" that includes photographs of the works exhibited along with detailed explanati…
Etnoargumentos y discursos comunes en torno a un megaevento deportivo: La 32ª America's Cup vista por la sociedad anfitriona
2013
Entre 2004 y 2007, se celebró en Valencia, España, la 32ª edición de la America’s Cup, el evento deportivo más antiguo, el más prestigioso del mundo de la vela y uno de los de mayor impacto económico y mediático que existe en la actualidad a escala internacional. Aunque era la primera vez en que tal evento se celebraba en Europa los resultados fueron unánimemente considerados como un éxito de organización, asistencia y audiencias. Este artículo aborda un aspecto menos explorado de los megaeventos deportivos: las percepciones que sobre el mismo elaboraron los propios residentes. Para ello se realizó una investigación cualitativa –consistente en veinte entrevistas– que ha permitido identifica…
Identificando emociones en el museo: Arte vs Alzheimer
2013
Presentamos el proceso metodológico de la investigación que, en la Universidad de Murcia, se está desarrollando sobre la identificación de emociones en personas con Enfermedad de Alzheimer (EA) inmersas en experiencias artístico- museísticas. Así, este trabajo resume parte de un proyecto más amplio cuya meta última es proponer un proceso de intervención y mediación cultural en personas con EA, para mejorar su calidad de vida y propiciar su inclusión social. La EA degenera progresivamente el estado emocional, la memoria semántica, el lenguaje y la capacidad comunicativa, por ello el lenguaje no verbal es nuestra principal fuente de información. El arte ha sido utilizado como un medio de com…