Search results for "SID"

showing 10 items of 6756 documents

PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.

2011

We investigated the therapeutic potential of the premature termination codon (PTC) readthrough-inducing drug PTC124 in treating the retinal phenotype of Usher syndrome, caused by a nonsense mutation in the USH1C gene. Applications in cell culture, organotypic retina cultures, and mice in vivo revealed significant readthrough and the recovery of protein function. In comparison with other readthrough drugs, namely the clinically approved readthrough-inducing aminoglycoside gentamicin, PTC124 exhibits significant better retinal biocompatibility. Its high readthrough efficiency in combination with excellent biocompatibility makes PTC124 a promising therapeutic agent for PTCs in USH1C, as well a…

virusesUsher syndromeGenetic enhancementNonsense mutationGenetic VectorsCell Cycle ProteinsRetina03 medical and health scienceschemistry.chemical_compoundMice0302 clinical medicineIn vivootorhinolaryngologic diseasesGeneticsmedicineAnimalsHumansMolecular BiologyCells Cultured030304 developmental biologyAdaptor Proteins Signal TransducingGenetics0303 health sciencesOxadiazolesbusiness.industryfungiAminoglycosideTranslational readthroughmedicine.diseasePhenotype3. Good healthAtalurenMice Inbred C57BLCytoskeletal ProteinsLuminescent ProteinsElectroporationchemistryMicroscopy FluorescenceCodon NonsenseCancer researchMolecular MedicineGentamicinsbusinessUsher Syndromes030217 neurology & neurosurgeryHuman gene therapy
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Demo 59. Densidad y viscosidad

2013

Objetivo: Entender que la densidad y la viscosidad son conceptos independientes.

viscosidaddensidadfluidosArquímedes
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Demo 62. Viscosidad. Ley de Newton

2013

Objetivo: Observar la influencia de las distintas variables en la ecuación de Newton de la viscosidad.

viscosidadfluidos
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不同情绪面孔的视觉工作记忆表现差异 [The Performance Difference of Visual Working Memory between Various Emotional Faces]

2022

Among social-emotional stimuli, emotional faces occupy an important position, which specifically refer to human faces with certain facial expressions. The visual working memory is a limited workspace where information can be saved online and can be accessed and operated by advanced cognitive function during the maintenance period. A large number of behavioral and electrophysiological studies have shown that there are differences in visual working memory performance of different emotional faces. Specifically, angry faces can enhance the visual working memory performance; fearful faces may cause some damage to visual working memory; sad faces will impair face recognition encoding in visual wo…

visual working memoryvisuaalisuusemotional facesilmeetnäkömuistievent related potentialtyömuistikasvotERPtapahtumasidonnaiset jännitevasteetmuisti (kognitio)
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Energia pulita dagli scarti della produzione vitivinicola

2009

viticoltura tesidui colturali emissioni co2Settore AGR/02 - Agronomia E Coltivazioni Erbacee
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Regional Farmers’ Perception and Societal Issues in Vineyards Affected by High Erosion Rates

2021

We explore the current situation in a viticultural region in Eastern Spain from a holistic and multifaceted research approach, which allowed us to understand the biophysical conditions, economic cost, social impact, and perception of the farmers’ community to the use of catch crops. A survey of the perception of the farmers, and an assessment of the biophysical impact of catch crops (CC) and tillage (C = Control plot) on soil organic matter, bulk density, infiltration capacity (single ring infiltrometer), and runoff generation and soil erosion (rainfall simulation experiments) was carried out. Two representative fields as study sites were selected in Les Alcusses valley, within Els Alforins…

viticultural areasLand managementcatch crops010501 environmental sciences01 natural sciencessoillcsh:AgricultureAgricultural scienceEconomic cost0105 earth and related environmental sciencesNature and Landscape ConservationGlobal and Planetary ChangeEcologySoil organic matterland managementlcsh:SSubsidy04 agricultural and veterinary sciencessustainabilityTillageGeographyregional geographical approach040103 agronomy & agricultureLand degradation0401 agriculture forestry and fisheriesCatch cropSurface runoffLand
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Journalistien suhtautuminen Suomen Punaisen Ristin Veripalveluun

2004

voitotmielikuvatSuomen punaisen ristin veripalveluluottamusyhteiskuntavastuumediaorganisaatiotsidosryhmätjournalistitvoittoa tavoittelematon organisaationon-profit organization
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Regulación del volumen plasmático en el ejercicio: papel de la intensidad y la adaptación al entrenamiento.

2016

La función del sistema circulatorio es la de mantener el entorno celular apropiado para el correcto desarrollo y supervivencia de los tejidos, aportando nutrientes, O2, y hormonas, al mismo tiempo que se retiran productos de desecho y CO2 (Guyton and Hall 2006b). Por tanto, el sistema circulatorio juega un papel fundamental en el mantenimiento de la homeostasis (Cannon 1929). Para cumplir esta misión, es fundamental mantener el flujo sanguíneo en todos los tejidos del organismo en función de las necesidades. El sistema circulatorio regula el flujo sanguíneo en todo el cuerpo mediante diversos mecanismos de feedback que modulan el gasto cardíaco (Q), la presión sanguínea y la distribución lo…

volumen plasmaticoUNESCO::CIENCIAS DE LA VIDAviscosidadintesidad:CIENCIAS DE LA VIDA [UNESCO]
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Compte rendu de : Violaine Girard, Le Vote FN au village. Trajectoires de ménages populaires du périurbain, Paris, Éditions du Croquant, 2017, 320 p.

2017

International audience

vote Front nationalprofessionnelles et résidentielles[ SHS.HIST ] Humanities and Social Sciences/Historyracisme institutionnel[SHS.HIST] Humanities and Social Sciences/Historyzones pavillonnairestrajectoires socialesélectorat d’extrême droite[SHS.HIST]Humanities and Social Sciences/HistoryComputingMilieux_MISCELLANEOUSpériurbain
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Practicing Ballot Secrecy: Postal Voting and the Witness Requirement at the 2019 Finnish Elections

2021

Electoral rights belong to the core of citizenship in democratic nation-states. Voting, then, represents an actualization of the relationship between the citizen and the political community. For citizens living outside the country in which they are eligible to vote, voting signifies a rare institutional connection to the country of origin. The aim of this article is to explore the introduction of the postal vote, a new form of voting for external voters at Finnish elections, from the grassroots perspective. The study focuses on how a central policy concern, safeguarding ballot secrecy, was resolved in the policy implementation by the witness requirement, and how the individual voters subseq…

votingnon-resident citizenselectoral practicesballot secrecypostal votingPolitical scienceFinlandJFrontiers in Political Science
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