Search results for "SIDE"
showing 10 items of 2895 documents
What can visual caregivers expect with patients treated for SARS-CoV-2? An analysis of ongoing clinical trials and ocular side effects
2020
Within the COVID-19 pandemic context, the WHO has proposed a list of medicines to treat patients with severe acute respiratory syndrome (SARS-CoV-2). An analysis of their ocular side effects was performed. Only chloroquine and hydroxychloroquine were found to have an ocular impact in the medium and long-term. Detailed search strategies were performed in EMBASE, MEDLINE, SCOPUS and WOS Core Collection. Additionally, the worldwide ongoing clinical trials including chloroquine or hydroxychloroquine were evaluated, and their proposals of drug administration and exclusion criteria analyzed. In general, high maximum cumulative doses of chloroquine or hydroxychloroquine are being used for a short…
At-home laser treatment of oral neuronal disorders : case reports
2017
The neuronal disorders occurring in the oral district are mainly anaesthesia, paraesthesia, hypoesthesia and hyperaesthesia and they may occur frequently after surgical procedures. Medical treatment depends on degree of severity of the nerve injury but, in every case, it must be immediately carried out to reduce immune inflammatory reaction. The aim of this report is to investigate the effectiveness in the recovery of the peripheral nerve lesions of a new laser device recently proposed by the commerce that, due to its reduced size and to be a class I laser according the ANSI classification, may be used at home by the patient himself. Three different cases were treated with this "at-home app…
Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy.
2016
Various, diverse molecules contribute to the tumor microenvironment and influence invasion and metastasis. In this review, the roles of neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) in the tumor microenvironment and sensitivity to therapy will be discussed. The lipocalin family of proteins has many important functions. For example when NGAL forms a complex with MMP-9 it increases its stability which is important in cancer metastasis. Small hydrophobic molecules are bound by NGAL which can alter their entry into and efflux from cells. Iron transport and storage are also influenced by NGAL activity. Regulation of iron levels is important for survival…
An exploration of digital ride-hailing multisided platforms' market dynamics: empirical evidence from the Uber case study
2020
PurposeThe purpose of this paper is to experiment a dynamic performance management (DPM) approach to explore and assess the business dynamics of digital ride-hailing platforms with a focus on both supply and demand sides, and related interplays.Design/methodology/approachThe research adopts the DPM framework supported by simulation-based experimentations for developing a systemic case interpretation of Uber Inc. and its specific business complexity.FindingsThe emerging scenario analysis reveals that changes in the commission percentage for drivers and cutting prices for customers (car hailers) by competitors have significant impacts on the car-hailing industry.Originality/valueDPM and assoc…
Towards identifying drug side effects from social media using active learning and crowd sourcing.
2019
Motivation Social media is a largely untapped source of information on side effects of drugs. Twitter in particular is widely used to report on everyday events and personal ailments. However, labeling this noisy data is a difficult problem because labeled training data is sparse and automatic labeling is error-prone. Crowd sourcing can help in such a scenario to obtain more reliable labels, but is expensive in comparison because workers have to be paid. To remedy this, semi-supervised active learning may reduce the number of labeled data needed and focus the manual labeling process on important information. Results We extracted data from Twitter using the public API. We subsequently use Ama…
Diversity of root-associated fluorescent pseudomonads as affected by ferritin overexpression in tobacco
2007
A transgenic tobacco overexpressing ferritin (P6) was recently shown to accumulate more iron than the wild type (WT), leading to a reduced availability of iron in the rhizosphere and shifts in the pseudomonad community. The impact of the transgenic line on the community of fluorescent pseudomonads was assessed. The diversity of 635 isolates from rhizosphere soils, rhizoplane + root tissues, and root tissues of WT and P6, and that of 98 isolates from uncultivated soil was characterized. Their ability to grow under iron stress conditions was assessed by identifying their minimal inhibitory concentrations of 8-hydroxyquinoline for each isolate, pyoverdine diversity by isoelectrofocusing and ge…
Dialogue between workers and family members is related to their attitudes towards self-determination of individuals with intellectual disability
2018
Background: This study focused on attitudes of workers and family members towards self-determination of individuals with intellectual disability. First, we compare their self-determination attitude...
Employers’ attitudes towards labour inclusion of persons with borderline intellectual functioning (BIF): An empirical evidence
2020
In the vocational rehabilitation of persons with disabilities (BIF), the need to consider the variables related to employer demand is increasingly becoming an important research topic. This empirical research explores the perceptions and attitudes of employers in hiring and retaining people with borderline intellectual functioning (BIF). For this purpose, the Metaplan procedure was used and a focus group was conducted in small and medium enterprises (SMEs) of the Spanish Vinalopó Footwear Cluster. Results showed a significant lack of knowledge and visibility of people with BIF. Lack of financial support to encourage hiring was pointed out by participants in the group as the most relevant ba…
Foreign Language learning and teaching Enjoyment: Teachers’ Perspectives
2019
Aim. The primary objective of the present study was to investigate the level of Foreign Language learning Enjoyment and Foreign Language teaching Enjoyment experienced by foreign language teachers in Poland. The secondary aim of the study was to investigate the sources of FLE from the perspective of FL teachers.
 Methods. The informants of the study were Polish educators teaching foreign languages at different educational levels (from primary to tertiary education). To compute the obtained quantitative data, the statistical program STATISTICA was used. Standard descriptive and inferential statistics were used to report means, median and standard deviation for sociodemographic and base…
Us and them: intercultural sensitivity of Polish and Georgian adolescent multilinguals
2020
The aim of this study is to compare the levels of intercultural sensitivity (IS) in teenage multilinguals coming from two post-communist countries: Poland (N=293) and Georgia (N=240). Aside from quantitative data the Intercultural Sensitivity Scale by Chen & Starosta., the qualitative part of the study focused on exploring quality of contacts with another culture. It was found that Polish students demonstrated significantly lower levels of intercultural sensitivity in spite of their greater foreign language experience. However, Georgian multilinguals demonstrated greater positive affect, both quantitatively (Intercultural Enjoyment as part of the IS assessment) and qualitatively (prevailing…