Search results for "SIM"
showing 10 items of 10139 documents
Metabolic detoxification: implications for thresholds.
2000
The fact that chemical carcinogenesis involves single, isolated, essentially irreversible molecular events as discrete steps, several of which must occur in a row to finally culminate in the development of a malignancy, rather suggests that an absolute threshold for chemical carcinogens may not exist. However, practical thresholds may exist due to saturable pathways involved in the metabolic processing, especially in the metabolic inactivation, of such compounds. An important example for such a pathway is the enzymatic hydrolysis of epoxides via epoxide hydrolases, a group of enzymes for which the catalytic mechanism has recently been established. These enzymes convert their substrates via…
Return Migration Process in Policy and Practice
2019
AbstractThis chapter focuses on return migration processes in Latvia, integrating analysis of return migration policy and the experiences of return migrants. The analysis considers the extent to which return policy activities correspond to the needs and expectations of the target group, and addresses the role of this policy in the process of making the decision to return. The data used for the analysis are policy planning documents, The Emigrant Communities of Latvia survey and in-depth interviews. The main empirical evidence of the return experiences of migrants in the chapter comes from 18 in-depth interviews with Latvian returnees from various age and social status groups, who left Latvi…
Generating Executable Code from High-Level Social or Socio-Ecological Model Descriptions
2019
Agent-Based Modelling has been used for social simulation because of the several benefits it entails. Social models are often constructed by inter-disciplinary teams that include subject-matter experts with no programming skills. These experts are typically involved in the creation of the conceptual model, but not the verification or validation of the simulation model. The Overview, Design concepts, and Details (ODD) protocol has emerged as a way of presenting a model at a high level of abstraction and as an effort towards improving the reproducibility of Agent-Based Models (ABMs) but it is typically written after a model has been completed. This paper reverses the process and provides non-…
Attention-based Model for Evaluating the Complexity of Sentences in English Language
2020
The automation of text complexity evaluation (ATCE) is an emerging problem which has been tackled by means of different methodologies. We present an effective deep learning- based solution which leverages both Recurrent Neural and the Attention mechanism. The developed system is capable of classifying sentences written in the English language by analysing their syntactical and lexical complexity. An accurate test phase has been carried out, and the system has been compared with a baseline tool based on the Support Vector Machine. This paper represents an extension of a previous deep learning model, which allows showing the suitability of Neural Networks to evaluate sentence complexity in tw…
Deep neural attention-based model for the evaluation of italian sentences complexity
2020
In this paper, the Automatic Text Complexity Evaluation problem is modeled as a binary classification task tackled by a Neural Network based system. It exploits Recurrent Neural Units and the Attention mechanism to measure the complexity of sentences written in the Italian language. An accurate test phase has been carried out, and the system has been compared with state-of-art tools that tackle the same problem. The computed performances proof the model suitability to evaluate sentence complexity improving the results achieved by other state-of-the-art systems.
Figure–Ground Spatial Relationships in Finnish Sign Language Discourse
2020
AbstractThis study is about expressing spatial relationships between Figure and Ground in Finnish Sign Language discourse and shows that the variation in this expression is primarily discourse dependent. The main findings are, first, that Ground mainly precedes Figure whether the Figure is new or a known referent within the discourse; the reverse order is possible only when the Figure is known. Second, the lexical signolla(‘have’) appears more frequently in expressing spatial relationships with a new Figure and less frequently with a known Figure but never in a construction with Figure preceding Ground; the formoli(‘had’), referring to the past, appears only in Figure preceding Ground const…
Multi-class Text Complexity Evaluation via Deep Neural Networks
2019
Automatic Text Complexity Evaluation (ATE) is a natural language processing task which aims to assess texts difficulty taking into account many facets related to complexity. A large number of papers tackle the problem of ATE by means of machine learning algorithms in order to classify texts into complex or simple classes. In this paper, we try to go beyond the methodologies presented so far by introducing a preliminary system based on a deep neural network model whose objective is to classify sentences into more of two classes. Experiments have been carried out on a manually annotated corpus which has been preprocessed in order to make it suitable for the scope of the paper. The results sho…
Breaking the Dominance of Dominant Voices: How the Therapist Promotes Assimilation by Facilitating Dialogue with the Client’s Problematic Voices
2019
Assimilation requires a dialogue between the client’s dominant and non-dominant internal voices, that is between the client’s usual self and his or her problematic experiences. This dialogue is est...
Elaborating the assimilation model: Introduction to a special section on case studies of setbacks within sessions and therapeutic collaboration
2016
AbstractThis article introduces a Special Section of case studies that focus on therapeutic collaboration and setbacks in the process of assimilation with the aim of contributing to the evolution of the assimilation model of therapeutic change. The first study examined setbacks in two depression cases (a good vs. a poor outcome) treated with emotion-focused therapy. The second article traced how therapist activities and positions toward internal voices were associated with setbacks in a case treated with linguistic therapy of evaluation. The third article studied contributions of therapeutic collaboration for both advances and setbacks in assimilation in two contrasting cases treated with e…
2017
Background/Objective: The Life Orientation Test-Revised (LOT-R) is often used to assess dispositional optimism. The aims of this study were to test psychometric properties of the LOT-R, to provide normative scores, and to test the association between optimism and several psychological, sociodemographic, and behavioral factors. Method: A randomly selected German general population community sample with an age range of 18-80 years (N = 9,711) was surveyed. Results: The Confirmatory Factor Analysis (CFA) proved two (correlated) factors: Optimism and Pessimism. Invariance tests across gender and age groups confirmed metric invariance. There were only small gender differences in the LOT-R total …