Search results for "SINS"

Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons

2011

Transport of mRNAs to diverse neuronal locations via RNA granules serves an important function in regulating protein synthesis within restricted sub-cellular domains. We recently detected the Huntington's disease protein huntingtin (Htt) in dendritic RNA granules; however, the functional significance of this localization is not known. Here we report that Htt and the huntingtin-associated protein 1 (HAP1) are co-localized with the microtubule motor proteins, the KIF5A kinesin and dynein, during dendritic transport of β-actin mRNA. Live cell imaging demonstrated that β-actin mRNA is associated with Htt, HAP1, and dynein intermediate chain in cultured neurons. Reduction in the levels of Htt, H…

Safety of Dietary Guanidinoacetic Acid: A Villain of a Good Guy?

2021

Guanidinoacetic acid (GAA) is a natural amino acid derivative that is well-recognized for its central role in the biosynthesis of creatine, an essential compound involved in cellular energy metabolism. GAA (also known as glycocyamine or betacyamine) has been investigated as an energy-boosting dietary supplement in humans for more than 70 years. GAA is suggested to effectively increase low levels of tissue creatine and improve clinical features of cardiometabolic and neurological diseases, with GAA often outcompeting traditional bioenergetics agents in maintaining ATP status during stress. This perhaps happens due to a favorable delivery of GAA through specific membrane transporters (such as…

Nursing Students’ Learning about Person-centred Dementia Care in a Nursing Home : A Qualitative Study

2022

It is unclear to what extent nursing students are able to apply person-centred care in practice, despite a mixture of educational support approaches. The aim of this study was to explore nursing students’ experiences of learning about person-centred dementia care after they participated in an adopted education programme in a nursing home. The education programme presented the main concepts of person-centred care. A qualitative explorative design was chosen where 32 bachelor-level nursing students participated in seven focus groups. The study is reported according to the COREQ checklist. Qualitative thematic content analysis revealed two main themes: care culture in the nursing home as joyf…

Social- and Health Care Educators’ Cultural Competence

2020

Introduction and aim: Cultural differences have significant impacts on classroom behaviours and communication in teaching. The aim of this study is to explore social and healthcare educators’ cultural competence in transcultural education. Methodology: Data was collected from semi-structured focus group interviews at universities of applied sciences and vocational colleges. Inductive content analysis was used in the analysis process. Results: Educators’ cultural competence in transcultural education emerges as generic categories: transcultural education, educatorship and ethical attitudes, and underpins by the sub-categories: language and linguistics, different learning styles, integrating …

Shared Situational Awareness in a Professional Soccer Team: An Explorative Analysis of Post-Performance Interviews

2020

Sport science research has done little to elaborate on the cognitive factors that turn a collection of individual players into a coordinated elite team. The purpose of this paper is to clarify if the players and coach of an elite soccer team express shared situational awareness. Ten players and one coach were exposed to twelve video pictures from a previous soccer match, and their statements for each picture were recorded and analyzed using a qualitative approach. Two of five game situations were with ball possession and three out of seven were without ball possession

"Jeg er ikke alene" : fatigue etter kreft: deltagernes erfaring med opphold på en rehabiliteringsgård

2016

Masteroppgave folkehelsevitenskap ME516 - Universitetet i Agder 2016 Konfidensiell til / confidential until 01.01.2022

Darba spriedze un farmaceitu darba spējas. Preventīvie pasākumi

2016

Mūsdienās arvien vairāk darbinieku saskaras ar psihosociālajiem riska faktoriem, kas iekļauj spriedzi darbā. Maģistra darbā analizēta darba spriedze un farmaceitu darba spējas, preventīvie pasākumi. Darba mērķis ir pētīt aptiekās strādājošo farmaceitu darba spriedzes līmeni un darba spējas, izstrādāt preventīvos pasākumus.Teorētiskajā daļā ir analizēti farmaceitu darba vides riski, kas strādā aptiekās, darba spriedzes jēdziens, darbspējas jēdziens. Pētījuma daļā ir apkopota un analizēta informācija par farmaceitu spriedzes iemesliem un esošajām darbspējām, noteikts darbspēju un darba spriedzes indekss, kā arī analizēti objektīvie spriedzes izvērtējumi: asinsspiediens, sirdsdarbības ritms, ķ…

André Gill. Derniers dessins d'un fou à lier

2010

Synthesis, structural, and thermal characterization of a new binuclear copper(II) chelate complex bearing an amine-hardener for epoxy resins

2016

A new di(μ-carbonato)bis[aqua(diethylenetriamine)copper(II)] hexahydrate complex, [{Cu(NH(C2H4NH2)2)(H2O)(μ-CO3)}2]⋅6H2O (1), was synthesized by direct interaction of malachite with diethylenetriamine (dien). The crystals of 1 were characterized by X-ray powder diffraction and IR spectra, as well as structurally characterized. Compound 1 consists of [{Cu(dien)(H2O)(μ-CO3)}2] discrete units whose CO32– anions play the role of bridging ligands combining two Cu(II) chelate cores into a centrosymmetric dimer. The elongated octahedral environment of Cu2+ consists of three nitrogens of dien and an oxygen from CO32– at the base of the bipyramid; the two apical positions of such polyhedron are occu…

Human Activity Signatures Captured under Different Directions Using SISO and MIMO Radar Systems

2022

In this paper, we highlight and resolve the shortcomings of single-input single-output (SISO) millimeter wave (mm-Wave) radar systems for human activity recognition (HAR). A 2×2 distributed multiple-input multiple-output (MIMO) radar framework is presented to capture human activity signatures under realistic conditions in indoor environments. We propose to distribute the two pairs of collocated transmitter–receiver antennas in order to illuminate the indoor environment from different perspectives. For the proposed MIMO system, we measure the time-variant (TV) radial velocity distribution and TV mean radial velocity to observe the signatures of human activities. We deploy the Anc…