Search results for "SJ"

showing 10 items of 2539 documents

Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020

Abstract Background Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety. Methods MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020. Results We identified 3 indirect pre-clinical studies and 28 clinical studies including 5776 patients with COVID-19 (13 with a comparison group,…

Coronavirus COVID-19 Pneumonia SARS-CoV-2 TocilizumabGCA Giant cell arteritispJIA Pediatric juvenile idiopathic arthritislaw.inventionchemistry.chemical_compound0302 clinical medicineRandomized controlled triallawMedicine030212 general & internal medicineClinical efficacyCPAP Continuous positive airway pressureCOVID-19 Coronavirus disease 2019IDSA Infectious Diseases Society of AmericaRA Rheumatoid arthritisTocilizumabIMV Invasive mechanical ventilationsJIA Juvenile idiopathic arthritisAIFA Agenzia Italiana del FarmacoPulmonary and Respiratory Medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEAntibodies Monoclonal HumanizedNIH U.S. National Institutes of HealthArticleWHO World Health OrganizationSIMIT Italian Society of Infectious and Tropical disease03 medical and health sciencesTocilizumabARDS Acute respiratory distress syndromeAnimalsHumansIn patientIntensive care medicineTocilizumab ; COVID-19 ; Pneumonia ; SARS-CoV-2 ; Coronaviruslcsh:RC705-779business.industryCRS CAR-T cell-induced cytokine release syndromeInterleukin-6SARS-CoV-2NIV Noninvasive mechanical ventilationTNF Tumor necrosis factorCOVID-19Pneumonialcsh:Diseases of the respiratory systemCOVID-19 Drug TreatmentClinical trialCoronavirus030228 respiratory systemchemistrybusinessICTRP International Clinical Trials Registry PlatformPulmonology
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E-learning in corporate training using interactive courses

2017

Master's thesis Multimedia and Educational Technology MM500 - University of Agder 2017 Health, safety, and environment (HSE) is an important term in industrial- and corporate context. A company focusing on their employees sharing the same values and attitudes regarding HSE can experience a working environment where employees feels safe, and perform their work without unnecessary risk-taking. There are often seen examples where HSE training relies on traditional classroom teaching, and keeps the focus on “do’s and “don’ts”, but the key to get employees to share a common goal on HSE, is to provide a deeper meaning for each employee on what this term actually mean. The purpose of this research…

Corporate traininghuman-centered designweb-based learningadult learningMM500technology acceptanceVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550::Annen informasjonsteknologi: 559Health Safety & Environment
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Corruption and managing the project cycle : the role of corrupt practices in NGO funding in Pakistan

2013

This Master’s thesis research explores the role of corrupt practices in development projects implemented by local NGOs in Pakistan. The intention is not to expose particular cases of corruption, but to study corruption risks and vulnerabilities in different phases of the project cycle and financial management (budgeting, accounting, financial reporting and auditing). It also explores other program support functions, i.e. procurement and human resources, and their vulnerability to corruption. The contribution of this study to academic literature is increasing awareness of NGO corruption and its different forms in Pakistan from the project management point of view. This is a qualitative study…

CorruptionlahjontaNon-governmental organizationskehitysyhteistyövarainhoitokorruptioAccounting – Corrupt PracticesPakistanProject cyclelaskentatoimiFinancial managementDevelopment cooperationkansalaisjärjestöt
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Simulations of networked critical infrastructures

2018

Master's thesis Information- and communication technology IKT590 - University of Agder 2018 Critical infrastructure (CI) refers to assets that are essential for the functioning of a society and economy, such as telecommunication/ICT; energy generation, transmission and distribution; financial sector; etc. CIs are tightly coupled, creating a complex system where failures propagate from a disrupted CI to other CIs, aggravating and prolonging the societal impact through cascading effects. This thesis extends a system dynamic model by Eliza Canzani describing how a failed critical infrastructure that cannot deliver products and services impacts other critical infrastructures, and how a critical…

Critical infrastructuresIKT590interdependenciessystem dynamics modellingVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550epidemics modelling
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The rising fear of terrorism and the emergence of a European security governance space: citizen perceptions and EU counterterrorism cooperation

2021

Among a wide range of challenges, EU member states have been facing a growing threat from terrorism in the recent years. The primary responsibility for combating terrorism lies with each individual member state, although the threat is becoming increasingly cross-border and diverse. Regardless of whether terrorism poses a real or perceived threat to the states’ and citizens’ security, public opinion is one important force behind the extensive counterterrorism efforts undertaken in Europe. In this article, we explore the influence of public opinion on EU policy within the security domain in the period 2005–19. We investigate the relationship between the number of attacks carried out on EU ter…

Cultural StudiesSecurity governanceSociology and Political ScienceMember statesmedia_common.quotation_subjectThreat perceptionSpace (commercial competition)VDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240Political sciencePerceptionPolitical economyPolitical Science and International RelationsTerrorismmedia_common
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Comparative evaluation of critical factors in Delivering service quality gaps in the Bangladeshi banking industry

2018

Master's thesis Business Administration BE501 - University of Agder 2018 This research study aims to search for the gaps in the quality of the service for the customers in different types of banks in Bangladesh. The study will evaluate the service quality gaps regarding different critical factors based on the SERVQUAL model which is initially established by Parasuraman. The relative importance and necessity of these vital factors in the evaluation of overall service qualitygaps investigated in the dominance analysis technique. This study was run by the questions and interviews of bank customers to find their perceptions about the service quality of selected Bangladeshi banks (Mary & Karl 20…

Customer’s ExpectationSERVQUAL ModelAssuranceCustomer’s PerceptionService QualityResponsivenessBE501TangibilityEmpathyVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242Bangladeshi Banks
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Desiccation resistance: effect of cuticular hydrocarbons and water content in Drosophila melanogaster adults

2018

Background.The insect cuticle covers the whole body and all appendages and has bi-directionnal selective permeability: it protects against environmental stress and pathogen infection and also helps to reduce water loss. The adult cuticle is often associated with a superficial layer of fatty acid-derived molecules such as waxes and long chain hydrocarbons that prevent rapid dehydration. The waterproofing properties of cuticular hydrocarbons (CHs) depend on their chain length and desaturation number. Drosophila CH biosynthesis involves an enzymatic pathway including several elongase and desaturase enzymes. Methods.The link between desiccation resistance and CH profile remains unclear, so we t…

CuticleDesaturaseAgricultural and Biological Sciences(all)EcologyDehydrationBiochemistry Genetics and Molecular Biology(all)Neuroscience(all)[SDV]Life Sciences [q-bio]lcsh:Rlcsh:Medicine/dk/atira/pure/subjectarea/asjc/1300Fat body/dk/atira/pure/subjectarea/asjc/1100GeneticsDrosophila/dk/atira/pure/subjectarea/asjc/2800Entomologydesaturase[SDV.AEN]Life Sciences [q-bio]/Food and NutritionInsectSelectionPeerJ
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Cytotoxic effects of antibodies to proteinase 3 (C-ANCA) on human endothelial cells.

1994

SUMMARY Autoantibodies directed against cytoplasmic antigens of neutrophils (ANCA), especially those with specificity for proteinase 3 (PR-3) and myeloperoxidase, are valuable markers for differential diagnosis and monitoring of disease activity in Wegener's granulomatosis (WG) and other vasculitides. Till now, several concepts concerning a direct role of antibodies against PR-3 in the pathogenesis of WG have been discussed. Recently we were able to show that these antibodies recognize PR-3 translocated into the membrane of human endothelial cells. The aim of this study was to investigate putative cytotoxic effects of antibodies to PR-3 on human endothelial cells. Antibodies were obtained b…

Cytotoxicity ImmunologicC-ANCAEndotheliumMyeloblastinImmunologyAutoantigensChromatography AffinityAntibodies Antineutrophil CytoplasmicAntigenProteinase 3medicineImmunology and AllergyCytotoxic T cellHumansLupus Erythematosus SystemicCells CulturedAutoantibodiesMixed Connective Tissue DiseasebiologySerine EndopeptidasesAntibody-Dependent Cell CytotoxicityGranulomatosis with PolyangiitisEndothelial stem cellmedicine.anatomical_structureSjogren's SyndromeMyeloperoxidaseImmunologybiology.proteinEndothelium VascularAntibodyResearch ArticleClinical and experimental immunology
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Obcy czy inni? Czesi w Zelowie

2018

We wstępnej części artykułu zostaną zaprezentowane kategorie OBCY, INNY oraz SWÓJ w różnych konfiguracjach (opozycja komplementarna, triada), obecnych w dyskursie tożsamościowym. Następnie przedstawione zostaną determinanty tożsamości: konfesja i język grupy mieszkańców Zelowa – potomków czeskich emigrantów religijnych. W końcowej części artykułu podkreśla się, że obraz potomków czeskich emigrantów jest zmienny w czasie: początkowo była to grupa homogeniczna pod względem wyznaniowym, etnicznym i językowym, a obecnie jest grupą zasymilowaną językowo i kulturowo.

Czechkategorie OBCYLinguistics and LanguageUSwyznaczniki tożsamości: język i konfesjadescendants of Czech religious emigrants in ZelówEthnic groupOpposition (politics)OTHERlanguage and confession [determinants of identity]INNYLanguage and Linguisticslanguage.human_languageGenealogycategories OTHEREmigrationcategories USpotomkowie czeskich emigrantów religijnych w Zelowiedeterminants of identity: language and confessionHomogeneous grouplanguageSociologycategories THEM (ALIEN)Electrical and Electronic EngineeringSWÓJ
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Brukertilfredshet i et elektronisk pasientjournalsystem – hva påvirker brukertilfredsheten? : Hva påvirker ansatte på et sykehus i Sør–Norges brukert…

2019

Masteroppgave helse- og sosialinformatikk HSI500 - Universitetet i Agder 2019 InnledningEtter hvert som befolkningen i Norge blir eldre og sykere er det et behov for informasjon om den enkelte pasient i helsevesenet. I Norge per i dag er det ingen felles journalløsninger som dekker alle nivåer i helsevesenet. Dette fører til at de som trenger informasjon ikke alltid har den nødvendige tilgangen. Det brukes forskjellige systemer avhengig av helseforetak, sykehus, kommune og lignende. På et sykehus i Sør –Norge brukes den elektroniske pasientjournalen (EPJ) DIPS, hvor alle nyansatte får opplæring før de gis tilgang til å dokumentere i DIPS. Denne studien forsøker å belyse opplæringens betydni…

DIPSelektronisk pasientjournalHSI500opplæringVDP::Samfunnsvitenskap: 200::Psykologi: 260::Sosial- og arbeidspsykologi: 263System Usability ScalebrukertilfredshetVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550
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