Search results for "SJ"
showing 10 items of 2539 documents
A frame shift mutation in a hot spot region of the nuclear autoantigen La (SS-B).
1996
A hot spot region was identified in the exon 7 of the nuclear autoantigen La (SS-B). Two La cDNAs were identified which contained a frame shift mutation in the hot spot region. One La cDNA was isolated from a cDNA library made from peripheral blood lymphocytes of an autoimmune patient with primary Sjogren's Syndrome, the other La cDNA was isolated from a human liver cDNA library. The patient's La cDNA had a deletion and the liver La cDNA had an insert of an (A)-residue at the same position. Inserts of 4, 16 and 24 more or less homogeneous (A)-residues were found at the same site in the three La retropseudogenes. The hot spot region located in one of the major autoepitope regions of the La a…
Analysis of expression of an alternative La (SS-B) cDNA and localization of the encoded N- and C-terminal peptides
1997
AbstractA deletion of an (A)-residue was detected in a cDNA encoding for the nuclear autoantigen La/SS-B. The cDNA was recently isolated from a cDNA library made from peripheral blood lymphocytes of a patient with primary Sjögren's Syndrome. The region, where the deletion occurred, represents a hot spot region in the La gene(s). It leads to a frame shift mutation and a premature stop codon eleven amino acids downstream of the deletion site within one of the protease sensitive regions of the La protein. In spite of the frame shift mutation expression of full length La protein occurred efficiently in E. coli. Full length La protein was also made in SF9 cells infected with recombinant baculovi…
A Decision-support Algorithm for Self-management of Anticoagulation Therapy Used in a Smartphone Application
2019
Warfarin for anticoagulation therapy is used by patients with specific cardiovascular diseases to control the ability of blood clotting. Traditional ways for self-management of the therapy are based on paper forms and procedures. This paper presents an algorithm developed for the smartphone application “Warfarin Guide”, which is a computer-assisted decision-support system used to help patients with self-management of their anticoagulation therapy related to International Normalized Ratio (INR) values. The algorithm was based on clinical guidelines for Warfarin therapy and it was adapted for the software application to address challenges with regular INR checks and adjustments for temporary …
A Simple and Efficient Deep Learning-Based Framework for Automatic Fruit Recognition
2022
Accurate detection and recognition of various kinds of fruits and vegetables by using the artificial intelligence (AI) approach always remain a challenging task due to similarity between various types of fruits and challenging environments such as lighting and background variations. Therefore, developing and exploring an expert system for automatic fruits’ recognition is getting more and more important after many successful approaches; however, this technology is still far from being mature. The deep learning-based models have emerged as state-of-the-art techniques for image segmentation and classification and have a lot of promise in challenging domains such as agriculture, where they can …
Heterometallic CoII-CoIII-MII alkoxido-bridged heptanuclear motifs (M = Cu, Zn). Syntheses, crystal structures and magnetic properties
2018
Two new alkoxido-bridged heterometallic complexes of formula [CoIICoIII 3CuII 3(dea)6(CH3COO)3](ClO4)0.75(CH3COO)1.25 (1) and [CoII 2CoIII 2ZnII 3(tea)2(piv)6(CH3O)2(OH)2(CH3OH)2]·H2O 2 (H2dea=diethanolamine, H3tea=triethanolamine and Hpiv=pivalic acid) have been assembled using aminoalcohol ligands. The cationic core in 1 possesses a threefold crystallographic axis, and it exhibits a set of three copper(II), one cobalt(II) and three cobalt(III) ions arranged as a hexagon of alternating copper(II) and cobalt(III) ions around the central cobalt(II) ion. Each edge of the hexagon is defined by a double alkoxido bridge, the outer one being bis-monodentate with copper(II)-cobalt(III) pair wherea…
Principio de jurisdicción universal y el conflicto árabe-israelí, Cristina García Pascual
2010
El muro de Cisjordania. Obstáculos para la garantía de los derechos humanos. Principio de jurisdicción universal y el conflicto árabe-israelí, Cristina García Pascual, Universitat de València. 11 de mayo de 2010. Institut Universitari de Drets Humans de la Universitat de València
El muro de Cisjoradina. Obstáculos para la garantía de los derechos humanos. Sobre el muro de Cisjordania y otros muros, Javier de Lucas. Preguntas (…
2010
El muro de Cisjordania. Obstáculos para la garantía de los derechos humanos. Presentación de las Jornadas, Consuelo Ramón (UV) y Lola Bañón (UNRWAce). Conferencia inaugural 'Sobre el muro de Cisjordania y otros muros' (preguntas). Javier de Lucas, Universitat de València. 3 de mayo de 2010. Institut Universitari de Drets Humans de la Universitat de València
Principio de jurisdicción universal y el conflicto árabe-israelí (debate), Cristina García Pascual
2010
El muro de Cisjordania. Obstáculos para la garantía de los derechos humanos. Principio de jurisdicción universal y el conflicto árabe-israelí (debate), Cristina García Pascual, Universitat de València. 11 de mayo de 2010. Institut Universitari de Drets Humans de la Universitat de València
Models Versus Model Descriptions
2021
In the development of computer-based systems, modelling is often advocated in addition to programming, in that it helps in reflecting the application domain and that it makes the design and experiment activities of development more efficient. However, there is disagreement about what models are and how they can be used in software systems development. In this paper, we present the Scandinavian approach to modelling, which makes a clear distinction between models and model descriptions. This paper explains the connections between models, descriptions, systems, and executions. Combining the Scandinavian approach with the Kiel notion of model, we establish that both descriptions and executions…
«Formalistic obscurantism»? An attempt to decipher the curriculum in social studies
2021
I 2020 trådte det nye læreplanverket, Kunnskapsløftet 2020, i kraft i norsk skole. I artikkelen har vi valgt samfunnsfaget i ungdomsskolen som eksempelstudium. Vi presenterer en detaljert, empirinær analyse av forholdet mellom kompetansemål, kjerneelementer og tverrfaglige tema i læreplanstrukturen for skolefag, samt forholdet mellom disse og overordnet del. Eksempelet er avgrenset til samfunnsfaget på ungdomsskolen, og basert på det forskriftsfestede planverket og den digitale støttemodulen. Funnene i denne delen av analysen gir praktisk kunnskap om læreplanene som er helt sentral for lærerutdannere og lærere, og som har overføringsverdi (og relevans) for fagdidaktikk for andre skolefag. I…