Search results for "SLI"
showing 10 items of 1729 documents
Hypertension in the metabolic syndrome: Summary of the new position statement of the European Society of Hypertension
2009
Arterial hypertension is often part of a larger constellation of anthropometric and metabolic abnormalities that includes abdominal (or visceral) obesity, characteristic dyslipidemia (low high-density lipoprotein cholesterol and high triglycerides), glucose intolerance, insulin resistance and hyperuricemia. Using Adult Treatment Panel III criteria, prevalence is higher than in the general population and the metabolic syndrome (MS) can be found in as many as one third of patients. In hypertensives with MS, a high prevalence of hypertension-induced target organ damage and a negative prognostic value have been described. Dietary advice and life style changes should be strongly recommended and …
282 Ophtalmologic follow-up of diabetic patients managed by Gps or diabetologists: results of FOCUS survey
2011
ObjectiveTo describe the ophthalmological follow up and cardiologists-nephrologists’ involvements in diabetic patients managed by GPs or diabetologists.MethodsTransversal and observational survey conducted in 2009, by 1112 GPs and 188 specialists.Results2577 diabetic patients (T1D or T2D) have been included; 63% were males, and mean age was 62 years. Mean diabetes duration was 10 years. Most of them were hypertensive (72%), 68% had a dyslipidemia and 30% a non proliferative diabetic retinopathy. Nearly all patients have been followed by ophthalmologists (70% have been seen once a year).In patients having a diabetic retinopathy (DR), treatments have been intensified in 80% of them with a vis…
Determinants of HIV outpatient service utilization according to HIV parameters
2014
Introduction : The increased life expectancy of HIV patients in the era of highly active antiretroviral therapy has had profound consequences for the healthcare systems that provide their care. It is useful to assess whether healthcare resources need to be adapted to the different stages of HIV infection or to patient characteristics [1]. To study how patient features influence utilization of out patient services, we retrospectively analyzed the electronic health record of HIV-positive patients who had followed day-care programs at the AIDS Center of the University of Palermo, Italy. Materials and Methods : 223 HIV-infected subjects were recruited and divided into two groups according to CD…
PMT: New analytical framework for automated evaluation of geo-environmental modelling approaches
2019
Geospatial computation, data transformation to a relevant statistical software, and step-wise quantitative performance assessment can be cumbersome, especially when considering that the entire modelling procedure is repeatedly interrupted by several input/output steps, and the self-consistency and self-adaptive response to the modelled data and the features therein are lost while handling the data from different kinds of working environments. To date, an automated and a comprehensive validation system, which includes both the cutoff-dependent and –independent evaluation criteria for spatial modelling approaches, has not yet been developed for GIS based methodologies. This study, for the fir…
Traditional vs. sliding-joint masonry infilled frames: Seismic reliability and EAL
2020
Abstract In reinforced concrete (RC) multi-storey buildings, the important role of the seismic interaction of structural frames with masonry infills has been revealed by several earthquakes and investigated by many authors. Recently, several innovative infill solutions have been proposed to mitigate such interaction, which could result in widespread damage in both the masonry and the RC structure and sometimes jeopardize the building stability and the occupants’ safety. One solution consists in the partitioning of the masonry infill into several sub-panels, relatively sliding along specific joints. This paper investigates the seismic assessment of this technological solution in the framewor…
Modelling anaerobic biomass growth kinetics with a substrate threshold concentration.
2004
Abstract Many bacteria have been observed to stop growing below a certain substrate threshold concentration. In this study, a modification of the Monod kinetics expression has been proposed to take into account this substrate threshold concentration observed in bacterial growth. Besides the threshold concentration no additional parameters have been added to the kinetic expression and so, only the substrate threshold concentration and the half-saturation constant have to be estimated for model calibration purposes. Furthermore, for parameter estimation purposes, practical identifiability of this new function has been studied and the results have been satisfactory. The new model has been appl…
Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview.
2021
Abstract Natural products and synthetic analogs have drawn much attention as potential therapeutical drugs to treat metabolic syndrome. We reviewed the underlying mechanisms of 32 natural products and analogs with potential pharmacological effects in vitro, and especially in rodent models and/or patients, that usually act on the PPAR pathway, along with other molecular targets. Recent outstanding total syntheses or semisyntheses of these lead compounds are stated. In general, they can activate the transcriptional activity of PPARα, PPARγ, PPARα/γ, PPARβ/δ, PPARα/δ, PPARγ/δ and panPPAR as weak, partial agonists or selective PPARγ modulators (SPPARγM), which may be useful for managing obesity…
Brief an Johann G. Herder.
1799
Ms. 930a, Nr. 17, Bl. 43r-44v Garlieb H. Merkel. Brief an Johann G. Herder. Berlin, d[en] 9ten März 1799 Autora rokraksts / Autograph, vācuval. / Deutsch [4] lpp. / S. Attēlu numuri / Bildnummern: 930a-017-1, 930a-017-2-3, 930a-017-4 Wahrscheinlich handelt es sich bei diesem Dokument um ein Konzeptdes Briefes von Merkel an Herder; es ist also nicht gesichert, ob dieser in Reinschrift verfasst undan den Adressaten abgeschickt wurde. Merkel schreibt sehr persönlich über sich selbst und versucht das Bild eines draufgängerischen Lebemannes zu geben, der seinen Horizont, wenn möglich, lieber durch eigene Erfahrungen als durch Buchlektüre erweitern will. Merkel weiß, dass er diese Sichtweise mit …
Iļja Mečņikovs
1945
Saturs: Iļjas Mečņikova dzīves gaita / P. Galenieks -- Mečņikova fagocitoze organisma imunitātes pamats / A. Kirhenšteins -- Iļjas Mečņikova nozīme medicīnā / P. Stradiņš.
Emerging approaches for the treatment of hypertriglyceridemia.
2013
Hypertriglyceridemia is frequent in diabetic and obese subjects, who are at increased risk for cardiovascular diseases (CVD). Increased triglycerides (TG) are a hallmark of atherogenic dyslipidemia, representing a marker of atherogenic small dense low-density lipoproteins (sdlDL). Importantly, non-fasting/postprandial TG measurements tend to be emphasized in clinical practice for the prediction of CVD, and TG-lowering agents (primarily fibrates) have a beneficial effect on atherogenic dyslipidemia, reducing TG-rich particles and ultimately lowering the production of sdlDL. The combination of omega-3 fatty acids and statins is also recommended, and widely used in clinical practice for subjec…