Search results for "SLO"

Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves.

2017

When a person is in a deep non-dreaming sleep, neurons in their brain alternate slowly between periods of silence and periods of activity. This gives rise to low-frequency brain rhythms called slow waves, which are thought to help stabilize memories. Slow wave activity can be detected on multiple scales, from the pattern of electrical impulses sent by an individual neuron to the collective activity of the brain’s entire outer layer, the cortex. But does slow wave activity in an individual group of neurons in the cortex affect the activity of the rest of the brain? To find out, Schwalm, Schmid, Wachsmuth et al. took advantage of the fact that slow waves also occur under general anesthesia, a…

Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis.

2020

Invasive aspergillosis (IA) is a life-threatening infection that affects an increasing number of patients undergoing chemotherapy or allo-transplantation, and recent studies have shown that genetic factors contribute to disease susceptibility. In this two-stage, population-based, case-control study, we evaluated whether 7 potentially functional single nucleotide polymorphisms (SNPs) within the ARNT2 and CX3CR1 genes influence the risk of IA in high-risk hematological patients. We genotyped selected SNPs in a cohort of 500 hematological patients (103 of those had been diagnosed with proven or probable IA), and we evaluated their association with the risk of developing IA. The association of …

CNS-Targeting Therapies for Lysosomal Storage Diseases: Current Advances and Challenges.

2020

During the past decades, several therapeutic approaches have been developed and made rapidly available for many patients afflicted with lysosomal storage disorders (LSDs), inborn organelle disorders with broad clinical manifestations secondary to the progressive accumulation of undegraded macromolecules within lysosomes. These conditions are individually rare, but, collectively, their incidence ranges from 1 in 2,315 to 7,700 live-births. Most LSDs are manifested by neurological symptoms or signs, including developmental delay, seizures, acroparesthesia, motor weakness, and extrapyramidal signs. The chronic and later-onset clinical forms are at one end of the continuum spectrum and are char…

Beware of the dog! Private linguistic landscapes in two ‘Hungarian’ villages in South-West Slovakia

2015

This study demonstrates how a single type of sign can be connected to language policy on a larger scale. Focusing on the relationship between language policy and language ideologies, I investigate the private Linguistic Landscape (LL) of Hungarians living in two villages in Slovakia. Through an examination of ‘beware of the dog’ signs, it is shown how such signs can be indicative of different language policies. In Slovakia, the Hungarian public LL is often referred to as a threat to the state language and public order. This ideology is reflected on the LL so that there are mostly Slovak-only public signs in bilingual and Hungarian dominant villages. The private realm is the only significant…

De Musica Disserenda, XII/1, 2016: Nineteenth-Century Music in Central Europe: Paradigms and Popular Canon

2016

Nations and nationalism have been a main research topic for decades, but the last few years have witnessed noticeable growth in these studies. The perspective generally accepted in the humanities – that demands for political independence of the nations in nineteenth-century Central Europe were premised on a sense of cultural identity – has also been taken up by contemporary musicological thought. Essays by philosopher and social anthropologist Ernest Gellner on “invented nations” in Nations and Nationalism (1983), or by historian and political scientist Benedict Anderson on “imagined communities” in Imagined Communities: Reflections on the Origin and Spread of Nationalism (1991), supported …

Analytical solution of kinematic wave time of concentration for overland flow under green-ampt infiltration

2015

In this paper the well-known kinematic wave equation for computing the time of concentration for impervious surfaces has been extended to the case of pervious hillslopes, accounting for infiltration. An analytical solution for the time of concentration for overland flow on a rectangular plane surface is derived using the kinematic wave equation under the Green-Ampt infiltration. The relative time of concentration is defined as the ratio between the time of concentration of an infiltrating plane and the soil sorptivity time scale, depending on the normalized rainfall intensity and a parameter synthesizing the soil and hillslope characteristics. It is shown that for a more complex case (corre…

Baltu filoloģija, 23. sēj., Nr.1

2014

"Table 3" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"

2022

Pb-remnant side ZN signal normalized to MB value vs. ZN centrality percentile in p-Pb collisions at 5.02 TeV

"Table 5" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"

2022

p-remnant side ZN signal normalized to MB value vs. ZN centrality percentile in p-Pb collisions at 5.02 TeV

"Table 9" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"

2022

p-remnant side ZN signal normalized to MB value vs. average Ncoll in p-Pb collisions at 5.02 TeV