Search results for "SMIS"

Starvation-induced expression of autophagy-related genes in Arabidopsis

2005

Background information. Autophagy is a catabolic process for degradation of cytoplasmic components in the vacuolar apparatus. A genome-wide survey recently showed evolutionary conservation among autophagy genes in yeast, mammals and plants. To elucidate the molecular and subcellular machinery responsible for the sequestration and subsequent digestion of intracellular material in plants, we utilized a combination of morphological and molecular methods (confocal laser-scanning microscopy, transmission electron microscopy and real-time PCR respectively). Results. Autophagy in Arabidopsis thaliana suspension-cultured cells was induced by carbon starvation, which triggered an immediate arrest of…

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance.

2009

Kinesin 2 family members are involved in transport along ciliary microtubules. In Caenorhabditis elegans channel cilia, kinesin II and OSM-3 cooperate along microtubule doublets of the axoneme middle segment, whereas OSM-3 alone works on microtubule singlets to elongate the distal segment. Among sensory cilia, vertebrate photoreceptors share a similar axonemal structure with C. elegans channel cilia, and deficiency in either kinesin II or KIF17, the homologue of OSM-3, results in disruption of photoreceptor organization. However, direct comparison of the two effects is confounded by the use of different species and knockdown strategies in prior studies. Here, we directly compare the effects…

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3.

2009

The Hsc/Hsp70 co-chaperones of the BAG (Bcl-2-associated athanogene) protein family are modulators of protein quality control. We examined the specific roles of BAG1 and BAG3 in protein degradation during the aging process. We show that BAG1 and BAG3 regulate proteasomal and macroautophagic pathways, respectively, for the degradation of polyubiquitinated proteins. Moreover, using models of cellular aging, we find that a switch from BAG1 to BAG3 determines that aged cells use more intensively the macroautophagic system for turnover of polyubiquitinated proteins. This increased macroautophagic flux is regulated by BAG3 in concert with the ubiquitin-binding protein p62/SQSTM1. The BAG3/BAG1 ra…

Invasion Ability and Disease Dynamics of Environmentally Growing Opportunistic Pathogens under Outside-Host Competition

2014

Most theories of the evolution of virulence concentrate on obligatory host-pathogen relationship. Yet, many pathogens replicate in the environment outside-host where they compete with non-pathogenic forms. Thus, replication and competition in the outside-host environment may have profound influence on the evolution of virulence and disease dynamics. These environmentally growing opportunistic pathogens are also a logical step towards obligatory pathogenicity. Efficient treatment methods against these diseases, such as columnaris disease in fishes, are lacking because of their opportunist nature. We present a novel epidemiological model in which replication and competition in the outside-hos…

Zvaigžņotā Debess: 2010/11, Ziema (210)

2010

Contents: “ZVAIGŅOTĀ DEBESS” FORTY YEARS AGO: Bursting Stars. J. Francman (abridged). Geodesists Help Renew the Spire of St. Peter’s Church. J. Klētnieks (abridged). DEVELOPMENTS in SCIENCE: The Solar Neutrino Problem. O. Smirnova. NEWS: At Last the Planet at the Star β Pictoris Is Imaged. A. Alksnis, Z. Alksne. SPACE RESEARCH and EXPLORATION: The Trail of an Asteroid Reveals a Recent Collision. A. Alksnis. INTERNATIONAL YEAR of ASTRONOMY 2009: International Year of Astronomy 2009 in Philately. The Rest of the World except Series EUROPA (concluded). J. Limansky. ACADEMIC STAFF of the UNIVERSITY of LATVIA: Assistant Professor in Physics Ojārs Šmits (24.04.1930.-14.03.1993.) of the Latvian Un…

Solid-State Synthesis of “Bamboo-Like” and Straight Carbon Nanotubes by Thermolysis of Hexa-peri-hexabenzocoronene–Cobalt Complexes

2006

ANCORA SULLA PORTATA DELLA NOZIONE DI “CESSAZIONE DELL’ATTIVITÀ D’AZIENDA” A PROPOSITO DEL LICENZIAMENTO DELLA LAVORATRICE MADRE NEL CORSO DI UNA PRO…

2018

Con la sentenza annotata la Corte di Cassazione torna a pronunciarsi sulla corretta interpretazione di una delle eccezioni al divieto di licenziamento sancito dall’art. 54 D. Lgs. n. 151/2001, chiarendo che nell’ipotesi di cessazione dell’attività d’azienda non può intendersi ricompresa anche la cessazione dell’attività di un singolo reparto, seppur dotato di autonomia funzionale. Nel ripercorrere il ragionamento seguito dai giudici, la nota richiama alcuni importanti principi in materia di licenziamento delle lavoratrici madri nel periodo protetto. The judgment in question makes a remark about the meaning of the exception to the prohibition of dismissal, according to the article 54 D. Lgs.…

Molecular detection of Bartonella spp. in deer ked pupae, adult keds and moose blood in Finland

2014

SUMMARYThe deer ked (Lipoptena cervi) is a haematophagous ectoparasite of cervids that harbours haemotrophic Bartonella. A prerequisite for the vector competence of the deer ked is the vertical transmission of the pathogen from the mother to its progeny and transstadial transmission from pupa to winged adult. We screened 1154 pupae and 59 pools of winged adult deer keds from different areas in Finland for Bartonella DNA using PCR. Altogether 13 pupa samples and one winged adult deer ked were positive for the presence of Bartonella DNA. The amplified sequences were closely related to either B. schoenbuchensis or B. bovis. The same lineages were identified in eight blood samples collected fro…

Robust Transmission for Reconfigurable Intelligent Surface Aided Millimeter Wave Vehicular Communications With Statistical CSI

2022

The integration of reconfigurable intelligent surface (RIS) into millimeter wave (mmWave) vehicular communications offers the possibility to unleash the potential of future proliferating vehicular applications. However, the high-mobility-induced rapidly varying channel state information (CSI) has been making it challenging to obtain the accurate instantaneous CSI (I-CSI) and to cope with the incurable high signaling overhead. The situation may become worse when the RIS with a large number of passive reflecting elements is deployed. To overcome this challenge, we investigate in this paper a robust transmission scheme for the time-varying RIS-aided mmWave vehicular communications, in which, s…

Design, implementation and experimental results of a wireless charger for E-bikes

2019

Based on the Inductive Power Transfer (IPT), the wireless energy transmission is increasingly representing an attractive solution for vehicle battery charging. Due to its high smartness, the wireless solution may be considered an interesting battery charging method for electric bicycles, as they represent light-weight and flexible means of transportation. According to the Vehicle-To-Grid (V2G) concept, the wireless power flow can occur in both the alternative directions: from the grid to the battery or in the opposite way. A Bi-Directional Inductive Power Transfer (BDIPT) system is therefore particularly convenient in the scenario of a multi-parking area. For the E-bike application, a bicyc…