Search results for "SMIS"

showing 10 items of 2316 documents

Haploinsufficiency of Tsc2 Leads to Hyperexcitability of Medial Prefrontal Cortex via Weakening of Tonic GABAB Receptor-mediated Inhibition.

2020

Abstract Loss-of-function mutation in one of the tumor suppressor genes TSC1 or TSC2 is associated with several neurological and psychiatric diseases, including autism spectrum disorders (ASDs). As an imbalance between excitatory and inhibitory neurotransmission, E/I ratio is believed to contribute to the development of these disorders, we investigated synaptic transmission during the first postnatal month using the Tsc2+/− mouse model. Electrophysiological recordings were performed in acute brain slices of medial prefrontal cortex. E/I ratio at postnatal day (P) 15–19 is increased in Tsc2+/− mice as compared with wildtype (WT). At P25–30, facilitated GABAergic transmission reduces E/I rati…

Cognitive NeurosciencePrefrontal CortexMice TransgenicHaploinsufficiencyGABAB receptorNeurotransmissionInhibitory postsynaptic potentialSynaptic TransmissionTonic (physiology)03 medical and health sciencesCellular and Molecular Neurosciencechemistry.chemical_compound0302 clinical medicineTuberous Sclerosis Complex 2 ProteinAnimalsPrefrontal cortex030304 developmental biologyNeurons0303 health sciencesChemistryElectrophysiologyBaclofenReceptors GABA-BExcitatory postsynaptic potentialNeuroscience030217 neurology & neurosurgeryCerebral cortex (New York, N.Y. : 1991)
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Active spike transmission in the neuron model with a winding threshold manifold

2012

International audience; We analyze spiking responses of excitable neuron model with a winding threshold manifold on a pulse stimulation. The model is stimulated with external pulse stimuli and can generate nonlinear integrate-and-fire and resonant responses typical for excitable neuronal cells (all-or-none). In addition we show that for certain parameter range there is a possibility to trigger a spiking sequence with a finite number of spikes (a spiking message) in the response on a short stimulus pulse. So active transformation of N incoming pulses to M (with M>N) outgoing spikes is possible. At the level of single neuron computations such property can provide an active "spike source" comp…

Cognitive Neuroscience[MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS][ MATH.MATH-DS ] Mathematics [math]/Dynamical Systems [math.DS][ NLIN.NLIN-CD ] Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD]Threshold manifoldBiological neuron modelMachine learningcomputer.software_genreTopology01 natural sciences010305 fluids & plasmaslaw.inventionSpike encodingArtificial Intelligencelaw0103 physical sciences010306 general physicsSpike transmissionActive responseBifurcationMathematicsExcitabilityQuantitative Biology::Neurons and Cognitionbusiness.industry[SCCO.NEUR]Cognitive science/NeuroscienceDissipationComputer Science ApplicationsPulse (physics)[SPI.TRON]Engineering Sciences [physics]/Electronics[ SPI.TRON ] Engineering Sciences [physics]/ElectronicsNonlinear systemTransmission (telecommunications)Nonlinear dynamics[NLIN.NLIN-CD]Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD][ SCCO.NEUR ] Cognitive science/NeuroscienceSpike (software development)Artificial intelligencebusinessManifold (fluid mechanics)computer
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I LICENZIAMENTI COLLETTIVI NELL’ORDINAMENTO MULTILIVELLO: EFFETTIVITÀ, DISSUASIVITÀ, NON DISCRIMINAZIONE

2020

L'articolo analizza la recente lettura delle corti di merito della normativa in materia di licenziamenti collettivi alla luce della Carta Sociale Europea, ed evidenzia la discriminazione rimediale tra lavoratori assunti prima e dopo il 7 marzo 2015, data di entrata in vigore del d.lgs. 23/2015. The article focuses on the recent jurisprudence of first instance labour courts on collective dismissals in the light of the European Social Charter, and it underlines the discrimination in terms of applicable remedies among workers hired before and after 7th March 2020, date of entry into force of legislative decree 23/2015.

Collective dismissals European Social Charter remedies discriminations.Settore IUS/07 - Diritto Del LavoroLicenziamenti collettivi Carta Sociale Europea tecniche di tutela discriminazioni.
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Synthesis of Hierarchically Grown ZnO@NT-WS2 Nanocomposites

2009

A chemically specific and facile method for growth of ZnO nanorods on WS2 nanotubes (NT-WS2) is reported. The modification strategy is based on the chalcophilic affinity of Zn, which serves as an anchor to immobilize ZnO colloids onto the WS2 nanotubes. The surface bound ZnO colloids have been used as a seed to grow ZnO nanorods on WS2 nanotubes. The immobilization of ZnO colloids was monitored by UV−vis spectroscopy and photoluminescence spectroscopy whereas the growth of ZnO nanorods was characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM).

ColloidNanocompositePhotoluminescenceMaterials scienceTransmission electron microscopyScanning electron microscopeGeneral Chemical EngineeringMaterials ChemistryNanorodNanotechnologyGeneral ChemistrySpectroscopy
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The fine structural organization of sternal glands of pseudergates and workers in termites (Isoptera): a comparative survey

2008

1873-5495 (Electronic) Comparative Study Journal Article; Thirty-nine species belonging to different families of termites are studied to give a comprehensive view of the evolution of the sternal glands. Several modifications occurring at cuticular and cytological levels are described in neuter castes. The outer epicuticle is always pierced by epicuticular pores. In advanced termites the epicuticular filaments greatly increase in number and length creating a thick layer. The pore canals gradually enlarge while the cuticle changes into a lattice structure lining an extracellular space in which the secretion is stored. Two classes of cells are present in basal termites (Mastotermitidae, Hodote…

Comparative/methodsCampaniform sensillaTermopsidaeKalotermitidaeArthropod cuticleIsopteraBiologyElectronPheromonesExocrine GlandsMicroscopy Electron TransmissionSpecies SpecificitySense Organs/physiologyPheromones/physiologyAnimalsEcology Evolution Behavior and SystematicsCuticle (hair)MicroscopyTransmission/veterinarySense OrgansGeneral MedicineAnatomybiology.organism_classificationTermitidaeAnatomy ComparativeHodotermitidaeInsect ScienceScanning/veterinaryMicroscopy Electron ScanningIsoptera/classification/physiology/*ultrastructureAnatomyRhinotermitidaeDevelopmental BiologyExocrine Glands/ultrastructure
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Conflict between parasites with different transmission strategies infecting an amphipod host

2005

Competition between parasites within a host can influence the evolution of parasite virulence and host resistance, but few studies examine the effects of unrelated parasites with conflicting transmission strategies infecting the same host. Vertically transmitted (VT) parasites, transmitted from mother to offspring, are in conflict with virulent, horizontally transmitted (HT) parasites, because healthy hosts are necessary to maximize VT parasite fitness. Resolution of the conflict between these parasites should lead to the evolution of one of two strategies: avoidance, or sabotage of HT parasite virulence by the VT parasite. We investigated two co-infecting parasites in the amphipod host, G…

Competitive BehaviorBehavior-altering parasites and parasitoidsVirulenceZoologyGeneral Biochemistry Genetics and Molecular BiologyAcanthocephalaHost-Parasite InteractionsGammarus roeseliAnimalsParasite hostingAmphipodaGeneral Environmental ScienceVirulenceGeneral Immunology and MicrobiologybiologyTransmission (medicine)Host (biology)ReproductionGeneral Medicinebiology.organism_classificationFertilityMicrosporidiaMicrosporidiaFemaleFranceGeneral Agricultural and Biological SciencesAcanthocephalaPolymorphism Restriction Fragment LengthResearch ArticleProceedings of the Royal Society B: Biological Sciences
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S1/4 Domain compliance and elastic power transmission in FOF1F0F1-ATPase

2008

Compliance (physiology)PhysicsPower transmissionbiologyATPaseBiophysicsbiology.proteinCell BiologyTopologyBiochemistryDomain (software engineering)Biochimica et Biophysica Acta (BBA) - Bioenergetics
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Preparation and characterisation of Ce:YAG -polycarbonate composites for white LED

2016

Ce:YAG-polycarbonate composites were prepared with several amounts of Ce:YAG in the range 0.1-5 wt.% by using melt compounding. The structure and morphology of the composites were investigated by means of X-ray diffractometry and transmission electron microscopy. The optical properties of the composites were studied by using photoluminescence spectroscopy. The intermolecular interaction between the polymer and the filler surface was investigated using 13C cross-polarization magic-angle spinning NMR spectroscopy (13C {1H} CP-MAS NMR). The results showed that the dispersion of the particles in the polymer, and the optical properties, depend on the Ce:YAG amount. The composites were combined w…

Composite materials Surfaces and interfaces Luminescence NanostructuresLuminescencePhotoluminescenceMaterials sciencegenetic structuresComposite number02 engineering and technology010402 general chemistry01 natural sciencesMaterials ChemistrySurfaces and interfacesPolycarbonateComposite materialSpectroscopySettore CHIM/02 - Chimica Fisicachemistry.chemical_classificationMechanical EngineeringMetals and AlloysComposite materialsPolymer021001 nanoscience & nanotechnologyeye diseasesNanostructures0104 chemical scienceschemistryMechanics of MaterialsTransmission electron microscopyvisual_artvisual_art.visual_art_mediumsense organs0210 nano-technologyDispersion (chemistry)LuminescenceJournal of Alloys and Compounds
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Table Compression

2016

Data Compression Techniques for massive tables are described. Related methodological results are also presented.

Compression and transmission of tableSettore INF/01 - InformaticaBig Data ManagementStorageCompressive estimates of entropyData Compression. Algorithms. Data structuresCompression of multidimensional data
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Exploring parallel capabilities of an innovative numerical method for recovering image velocity vectors field

2010

In this paper an efficient method devoted to estimate the velocity vectors field is investigated. The method is based on a quasi-interpolant operator and involves a large amount of computation. The operations characterizing the computational scheme are ideal for parallel processing because they are local, regular and repetitive. Therefore, the spatial parallelism of the process is studied to rapidly proceed in the computation on distributed multiprocessor systems. The process has shown to be synchronous, with good task balancing and requiring a small amount of data transfer.

ComputationNumerical analysisProcess (computing)MultiprocessingField (computer science)Computational scienceComputer Science ApplicationsSettore MAT/08 - Analisi NumericaOperator (computer programming)Parallel processing (DSP implementation)Modeling and SimulationModelling and SimulationImage velocity vectors field Quasi-interpolant operator B-spline functions Distributed multiprocessor systemsAlgorithmMathematicsData transmissionMathematical and Computer Modelling
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