Search results for "SMR"

How do skeletal morbidity rate and special toxicities affect 12-week versus 4-week schedule zoledronic acid efficacy? A systematic review and a meta-…

2019

Abstract Background Zoledronic Acid is a bisphosphonate used in a 4-week schedule for the treatment of bone metastases. Some randomized trials supported its role also when administered every 12 weeks. Methods we performed a systematic review and a meta-analysis in order to evaluate the two different schedules in terms of skeletal morbidity rate (SMR), skeletal related events (SRE) and adverse events (AEs). Results our results showed a clinical difference favouring the 12-week schedule in terms of AEs (RR 1.17, 95% CI 1.06–1.29). No signifcant differences were found for SMR (RR 0.97, 95% CI 0.84–1.13) and SRE (RR 1.02, 95% CI 0.89–1.16). Conclusions Our findings support in clinical practice …

Primjena ekstrakta proteina sirutke u proizvodnji smrznutog mliječnog deserta

2018

The aim of this work was to substantiate the use of whey protein extract (WPE), a by-product of dairy industry, combined with different berry purees in the formulation of a whipped frozen dairy dessert (WFDD). After freezing, the swelling ability of WPE decreased significantly while at higher temperatures of the dispersion medium, the degree of swelling increased. A mixture containing 55±2 % WPE and 45±2 % milk presented a homogeneous consistency while the further processing did not improve the structure of the mixture. Final formulations of WFDD containing different berry purees (i.e. 10 % black¬currant puree, 25 % cherry puree, or 30 % strawberry puree) were proposed for which the nutriti…

Musically induced ASMR : an amalgamated experience

2015

Musically induced ASMR is an Autonomous Sensory Meridian Response triggered by music. The term ASMR is best known on the internet by communities who report experiencing this phenomenon. It is most simply understood as an experience like musical chills, however can be triggered by nearly any form of stimuli. The current study employed grounded theory, a meticulous and established qualitative research method for developing theory that serves to explain salient characteristics of a particular phenomenon; to theorize the nature and significance of musically induced ASMR and ASMR in general. Based on the data collected, the study confirmed the existence of musically induced ASMR and demonstrates…

Analysis of the OSU-MASLWR-003A natural circulation test by using the trace code

2012

TRACE Code Analyses for the IAEA ICSP on “Integral PWR Design Natural Circulation Flow Stability and Thermo-Hydraulic Coupling of Containment and Pri…

2011

Considering the world energy demand increase in order to fulfill an environmental and economic sustainability, the energy policy of each country has to diversify the sources of energy and use stable, safe energy production option able of producing electricity in a clean way contributing in cutting the CO2 emission. In the framework of the sustainable development, today the use of advanced nuclear power plant, have an important role in the environmental and economic sustainability of country energy strategy. In the last 20 years, in fact, the international community, taking into account the operational experience of the nuclear reactors, starts the development of new advanced reactor designs…

TRACE and RELAP5 Codes for Beyond Design Accident Condition Simulation in the SPES3 Facility

2012

Code validation on qualified experimental data is a fundamental issue in the design and safety analyses of nuclear power plants. The SPES3 facility is being built at the SIET laboratories for an integral type SMR simulation, in the frame of an R&D program on nuclear fission, funded by the Italian Ministry of Economic Development and led by ENEA. The facility, based on the IRIS reactor design, reproduces the primary, secondary and containment systems with 1:100 volume scale, full elevation and prototypical fluid and thermal-hydraulic conditions. It is suitable to test the plant response to design and beyond design accidents in order to verify the effectiveness of the primary and containm…

Analyses of the OSU-MASLWR Experimental Test Facility

2012

Today, considering the sustainability of the nuclear technology in the energy mix policy of developing and developed countries, the international community starts the development of new advanced reactor designs. In this framework, Oregon State University (OSU) has constructed, a system level test facility to examine natural circulation phenomena of importance to multi-application small light water reactor (MASLWR) design, a small modular pressurized water reactor (PWR), relying on natural circulation during both steady-state and transient operation. The target of this paper is to give a review of the main characteristics of the experimental facility, to analyse the main phenomena characteri…

Analysis of a Station Black-Out transient in SMR by using the TRACE and RELAP5 code

2014

The present paper deals with the investigation of the evolution and consequences of a Station Black-Out (SBO) initiating event transient in the SPES3 facility [1]. This facility is an integral simulator of a small modular reactor being built at the SIET laboratories, in the framework of the R&D program on nuclear fission funded by the Italian Ministry of Economic Development and led by ENEA. The SBO transient will be simulated by using the RELAP5 and TRACE nodalizations of the SPES3 facility. Moreover, the analysis will contribute to study the differences on the code predictions considering the different modelling approach with one and/or three-dimensional components and to compare the capa…

ANALYSES OF THE SPES-3 DESIGN AND BEYOND DESIGN ACCIDENT CONDITION BY USING TRACE CODE

2012

Sensitivity Analysis of the MASLWR Helical Coil Steam Generator Using TRACE

2011

Accurate simulation of transient system behavior of a nuclear power plant is the goal of systems code calculations, and the evaluation of a code's calculation accuracy is accomplished by assessment and validation against appropriate system data. These system data may be developed either from a running system prototype or from a scaled model test facility, and characterize the thermal hydraulic phenomena during both steady state and transient conditions. The identification and characterization of the relevant thermal hydraulic phenomena, and the assessment and validation of thermal hydraulic systems codes, has been the objective of multiple international research programs. The validation and…