Search results for "SNOT-22"
showing 3 items of 3 documents
Effects of Omalizumab Treatment in Patients With Recalcitrant Nasal Polyposis and Mild Asthma: A Multicenter Retrospective Study
2021
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a clinical entity with specific features that impacts significantly on patient quality of life (QoL). CRSwNP is often associated with asthma and is difficult to control and manage despite pharmacological and/or surgical treatment. Omalizumab, a monoclonal anti-IgE antibody, has emerged as a putative therapeutic option. Objective To evaluate the effects of omalizumab on nasal polyp (NP) size and QoL assessed by Sino-Nasal Outcome Test-22 (SNOT-22) in patients with recalcitrant CRSwNP and mild asthma. Methods A multicenter retrospective analysis of patient data from the Community of Valencia (Spain) was performed. Adult patients …
The prognostic value of subjective nasal symptoms and SNOT-22 score in middle ear surgery
2022
Background: The relationship between nasal functions and middle ear surgery is still under debate. Nasal obstruction is considered as a negative prognostic factor in middle ear surgery. This is based on the theory that it may cause Eustachian tube dysfunction (ETD) by leading to reduced ventilation of the middle ear, as found in several patients with nasal septal deviation, chronic rhinitis and nasal polyps. Objectives: To assess how the subjective feeling of nasal function, evaluated by a preoperative questionnaire, may be predictive of surgical outcome and/or risk of failure in middle ear surgery. Methods: We prospectively evaluated data of patients undergoing middle ear surgery for chron…
Correlaciones clínicas, morfológicas y de calidad de vida en pacientes afectos de rinosinusitis crónica con poliposis nasal
2021
INTRODUCCIÓN La rinosinusitis crónica con pólipos nasosinusales (RSCcPN) es una en-fermedad desafiante que tiene un impacto significativo en la calidad de vida (CdV) de los pacientes. Los eosinófilos se consideran las células in-flamatorias más importantes en la patogénesis de la rinosinusitis con pólipos nasales. La posibilidad de predecir la CdV en los pacientes con RSCcPN permitiría optimizar su manejo y mejorar los resultados. OBJETIVO Conocer la asociación entre la CdV mediante el cuestionario Sinonasal Outcome Test -22 (SNOT-22) y parámetros histopatológicos y molecula-res (incluyendo eosinofilia y expresión de Mucina 1 –MUC1) en pacien-tes con RSCcPN. Los objetivos secundarios incluy…