Search results for "SNi"

Structure of rat behavior in hole-board: II) multivariate analysis of modifications induced by diazepam.

2009

In our previous study we suggested that multivariate analysis could improve hole-board test reliability providing a more useful tool to determine behavioral effects of anxiolytic drugs. To support this hypothesis, a multivariate analysis of rat behavior in hole-board, following administration of the reference anxiolytic drug diazepam, was carried out. Four groups, each composed of thirty male Wistar rats, were used: one saline and three diazepam injected (0.25, 0.5 and 2 mg/kg IP). Rat behavior was recorded for 10 min through a digital videocamera. Descriptive and multivariate analyses were carried out. In all groups, more than 80% of whole behavioral structure encompassed walking, climbing…

Microstructure of rat behavioral response to anxiety in hole-board

2010

Aim of present research was to assess, by means of descriptive and multivariate approaches, in Wistar rats tested in hole-board apparatus, whether a microstructure of hole exploratory behavior may be identified in the behavioral response to anxiety. Two groups of 15 subjects were tested: one received 1 ml of saline IP and one was IP injected with diazepam at 0.5 mg/kg dissolved in 1 ml of saline. Following saline, six not yet reported hole-exploratory components were identified: active-dip, static-dip, rapid-dip, circular-sniff, point-sniff and central-sniff. Diazepam provoked significant changes of their per cent distribution. Results of multivariate analyses revealed a complex microstruct…

Analysis of the Relationship between Tobacco Smoking and Physical Activity in Adolescence: A Gender Specific Study

2021

Background and Objective: Although smoking and the physical activity level (PAL) are important determinants of health status in adolescence, there is a lack of information on the relationship between smoking and PAL in early adolescence. The objective of this study was to evaluate the gender-specific relationship between smoking and PAL in 14-to-16-year-old adolescents. Materials and Methods: The sample included 650 adolescents (337 girls, 14.7 ± 0.5 years at first testing wave) from Bosnia and Herzegovina. During the first testing wave, participants were tested using structured questionnaires. Second testing was commenced after approximately 20 months (16.4 ± 0.6 years). The variables were…

Exploring the Association between Alcohol Drinking and Physical Activity in Adolescence; Two-Year Prospective Study in Younger Adolescents from Bosni…

2021

Insufficient physical activity and alcohol consumption (AC) are important health-threatening behaviors in adolescence, but there are controversial findings regarding the association that may exist between AC and physical activity levels (PALs) at this age. This study aimed to prospectively examine the relationship that may exist between AC and PAL in younger adolescence, considering the potential confounding effect of sports participation. The participants (n = 669, 337 females) were adolescents from Bosnia and Herzegovina who were tested on two occasions, at baseline (14 years of age) and again at follow-up (16 years of age). The variables included AC (as indicated by the AUDIT questionnai…

Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats

2020

Understanding the importance of the gut microbiota (GM) in non-alcoholic fatty liver disease (NAFLD) has raised the hope for therapeutic microbes. We have shown that high hepatic fat content associated with low abundance of Faecalibacterium prausnitzii in humans and, further, the administration of F. prausnitzii prevented NAFLD in mice. Here, we aimed at targeting F. prausnitzii by prebiotic xylo-oligosaccharides (XOS) to treat NAFLD. First, the effect of XOS on F. prausnitzii growth was assessed in vitro. Then, XOS was supplemented or not with high (HFD, 60% of energy from fat) or low (LFD) fat diet for 12 weeks in Wistar rats (n = 10/group). XOS increased F. prausnitzii growth, having onl…

Starpdisciplinārie pētījumi medicīnas koledžās : tēžu krājums

2021

Latvijas Universitātes 79. starptautiskās zinātniskās konferences “Starpdisciplinārie pētījumi medicīnas koledžās” tēzes raksturo medicīnas koledžās veikto pētījumu daudzpusību, pētniecības kvalitāti un arī lietišķumu, kas šogad izceļas ar raksturvārdiem “drošība” un “atbildība”. Konferencē prezentēto un diskutēto jautājumu loks ievērojami pārsniedz veselības aprūpē apskatīto jautājumu loku un veicinās studentus, pētniekus un sociālos partnerus aktīvāk sadarboties ne tikai studiju kvalitātes uzlabošanā, bet arī pētniecībā.

Zvaigžņotā Debess: 2010, Rudens (209)

2010

Contents: G.Carevsky, I.Daube. Comet Bennett ; E.Fogels. Srinivasa Ramanujan ; M.Krastiņš. Smallest Planet of the Solar System: a Riddle of Centuries (1st part) ; A.Alksnis, Z.Alksne. Hot Jupiters and Their Retrograde Motion ; V.Karitāns. James Webb Space Telescope. What will it Be? ; K.Salmiņš. GFZ CHAMP Laser Tracking Award to SLR Station Riga ; J.Jansons. Vladimir Afanasjev, Officer of the Baikonur Cosmodrom in the 1970s (concluded) ; J.Limansky. International Year of Astronomy 2009 in Philately. Series EUROPA (2nd sequel) ; J.Dambītis. Centenary of Prominent Latvian Mathematician Ernests Fogels (1910-1985) ; J.Klētnieks. Sketches of History of Astronomy (concluded) ; M.Gills. Public Sun…

Гидрологические и метеорологические процессы и окружающая среда

1976

Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients

2019

Lynch syndrome (LS) is a dominantly inherited condition with incomplete penetrance, characterized by high predisposition to colorectal cancer (CRC), endometrial and ovarian cancers, as well as to other tumors. LS is associated with constitutive DNA mismatch repair (MMR) gene defects, and carriers of the same pathogenic variants can show great phenotypic heterogeneity in terms of cancer spectrum. In the last years, human gut microbiota got a foothold among risk factors responsible for the onset and evolution of sporadic CRC, but its possible involvement in the modulation of LS patients’ phenotype still needs to be investigated. In this pilot study, we performed 16S rRNA gene sequencing of ba…

Alma Mater: 2014/ rudens

2014

LU rektora M.Auziņa ievadraksts -- Novēlējumi Latvijas Universitātes 95 gadu jubilejā -- Andra Čudare. Indriķis Muižnieks – jauno zinātnieku labais gans -- Annija Petrova. InCell – māka pārvērst zinātnes potenciālu uzņēmējdarbībā -- Iveta Gudakovska. Universitātes skaistākais vēsturiskais nams -- Ivars Šteinbergs. Starp medicīnu un filozofiju -- Laila Kundziņa-Zvejniece. Filantropijas tradīcijas Latvijas Universitātē starpkaru laikā -- LU Preses centrs. LU vēstures laika josla -- Dace Silarāja. Latvijas Universitātes vienaudze – Milda Purīte -- Juris Borzovs. Kādai būt Latvijas Universitātei – 100? -- Aiga Leitholde. Studiju laikā vēlams būt maksimālistam -- Evija Ansonska. Latvijas Univers…