Search results for "SOM"

CZYM JEST ASZ-SZABAB? ZARYS ATAKU NA GALERIĘ HANDLOWĄ WESTGATE

2017

: We wrześniu 2013 roku światem wstrząsnęła informacja o krwawym zamachu w Nairobi. Mimo zaangażowania mediów w relacjonowanie całego zajścia samo zjawisko organizacji Asz-Szabab nie zostało wyczerpująco wyjaśnione. Autorzy artykułu podjęli więc próbę ukazania złożoności i stopnia skomplikowania całego zagadnienia. W pracy starano się w sposób obiektywny zbudować wizerunek Asz-Szabab, jak i przedstawić sposób jej działania w ujęciu bezpieczeństwa wewnętrznego głównie kontynentu Afrykańskiego i Europejskiego. Dokonano tego analizując szczegółowo sam zamach w Kenii, jak i codzienne działanie organizacji na swoim terenie. Zarysowano również tło historyczne oraz kulturowe w celu określenia waru…

Foucault: il potere oltre le regole. Repliche a Celano, Moreso, Segatti e Spena

2020

In questo articolo rispondo alle critiche e ai commenti alla mia ricostruzione della concezione del potere di Michel Foucault proposti da Bruno Celano, José Juan Moreso, Marco Segatti, Alessandro Spena. Mi concentro in particolare sui seguenti aspetti: la connessione fra la nozione foucaultiana di potere e il conflitto; la distinzione fra potere disciplinare, potere governamentale, e potere normativo; la concezione foucaultiana della libertà come autorialità; ciò che Foucault può suggerire riguardo ad alcune “macchie cieche” della teoria del diritto contemporanea.

On the Choice of the Extracellular Vesicles for Therapeutic Purposes

2019

Extracellular vesicles (EVs) are lipid membrane vesicles released by all human cells and are widely recognized to be involved in many cellular processes, both in physiological and pathological conditions. They are mediators of cell-cell communication, at both paracrine and systemic levels, and therefore they are active players in cell differentiation, tissue homeostasis, and organ remodeling. Due to their ability to serve as a cargo for proteins, lipids, and nucleic acids, which often reflects the cellular source, they should be considered the future of the natural nanodelivery of bio-compounds. To date, natural nanovesicles, such as exosomes, have been shown to represent a source of diseas…

Carboxylate catalyzed isomerization of β,γ‐unsaturated N-acetylcysteamine thioesters

2022

We demonstrate herein the capacity of simple carboxylate salts – tetrametylammonium and tetramethylguanidinium pivalate – to act as catalysts in the isomerization of β,γ-unsaturated thioesters to α,β-unsaturated thioesters. The carboxylate catalysts gave reaction rates comparable to those obtained with DBU, but with fewer side reactions. The reaction exhibits a normal secondary kinetic isotope effect ( k 1H / k 1D = 1.065±0.026) with a β,γ−deuterated substrate. Computational analysis of the mechanism provides a similar value ( k 1H / k 1D = 1.05) with a mechanism where γ-reprotonation of the enolate intermediate is rate determining. peerReviewed

Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives

2014

A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…

IDPlanT: the Italian database of plant translocation

2021

IDPlanT is the Italian Database of Plant Translocation, an initiative of the Nature Conservation Working Group of the Italian Botanical Society. IDPlanT currently includes 185 plant translocations. The establishment of a national database on plant translocation is a key step forward in data sharing and techniques improvement in this field of plant conservation. Supplemental data for this article is available online at https://doi.org/10.1080/11263504.2021.1985004.

ACTO II / ACT II Mujeres / Women ¿Es gay la música de Chopin? Aspectos de la recepción de la música de Chopin en el siglo XIX

2021

Considering that it is difficult, if not impossible, for an analysis of Chopin?s music to unmask some aspects of his private life (such as an alleged sexual and affective attraction for individuals of his own sex), we can however argue that, throughout the 19th century, a connection was established between his work and a ?feminine universe.? That connection might have had implications in the way in which the feminized image of its author was constructed. The analysis of certain aesthetic and stylistic traits of Chopin?s music can help understand the causes of that perception.

"Absolut ingen rädsla utan nyfikenhet" : tidigareläggning av finska – Case Nykarleby

2018

Nykarleby är en av de tvåspråkiga kommunerna som våren 2017 erhöll statens specialunderstöd för att tidigarelägga språkundervisningen i finska. Finskundervisningen i staden tidigarelades år 2016 till årskurs 1 men denna har redan konstaterats vara otillräcklig i en starkt svenskspråkig miljö. Därför har man under läsåret 2017–2018 planerat Kielistigen, ett språkprogram med målsättningen att stärka den kommunikativa finskan genom att börja med barn i femårsåldern samt integrera språket som en naturlig del av verksamheten från småbarnspedagogiken till grundskolan där språket integreras i övrig undervisning. nonPeerReviewed

Mies sanojensa takana : folkloristinen tutkimus Niilo Yli-Vainion ja muutaman vapaakristillisen kollegan esityksellisistä teksteistä ja kollektiivitr…

2005

Bending Work Time: Curvilinear Relationship Between Working Time Dimensions and Psychological and Somatic Symptoms.

2020

Objectives Study examines the curvilinear associations of working time dimensions (working hours, time pressure, work schedules, and control of work time and pace) on psychological and somatic symptoms. Methods Representative Finnish Quality-of-Work-Life Surveys conducted in 2003, 2008 and 2013 were restricted to those (N=11,165) regularly working over 10h/week with more than one-year tenure in their job. Generalised additive models were utilised in analysis. Results Working hours had U-shaped relationships with psychosomatic symptoms, while time pressure had a threshold effect. Work pace control had linear effect. The effects of work time control and work schedules were insignificant. Ther…