Search results for "SOMs"

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Weather Regimes in the Euro-Atlantic and Mediterranean sector and relationship with West African rainfall over the period 1989-2008 from a Self-Organ…

2011

International audience; Weather Regimes (WR) have been defined over the Euro-Mediterranean region [60°W-60°E; 15°N-70°N] from May to October season using the daily Sea Level Pressure, 700 hPa geopotential height and specific humidity from ERA-interim over 1989-2008 period. Computations are based on a neural network lassification technique referred to as Self Organizing Maps and the WR produced can be used by the community for comparison with other periods, projection onto model outputs, seasonal prediction or teleconnection studies. The article particularly examines the relationship between WR and West African (WA) rainfall and our results suggest that changes in particular WR frequencies c…

[ SDE.MCG ] Environmental Sciences/Global Changes[SDE.MCG] Environmental Sciences/Global Changes[SDU.STU.CL] Sciences of the Universe [physics]/Earth Sciences/ClimatologyWest African RainfallSOMs[SDU.STU.CL]Sciences of the Universe [physics]/Earth Sciences/Climatology[SDE.MCG]Environmental Sciences/Global ChangesMediterranean Sea[ SDU.STU.CL ] Sciences of the Universe [physics]/Earth Sciences/ClimatologyWeather Regimes
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1,4 dihidropiridinski derivati povećavaju ekspresiju gena Psma3, Psmb5 i Psmc6 u glasničkoj RNA štakora

2021

The ubiquitin-proteasome system modifies different cellular and protein functions. Its dysregulation may lead to disrupted proteostasis associated with multiple pathologies and aging. Pharmacological regulation of proteasome functions is already an important part of the treatment of several diseases. 1,4-dihydropyridine (1,4-DHP) derivatives possess different pharmacological activities, including antiaging and neuroprotective. The aim of this study was to investigate the effects of several 1,4-DHP derivatives on mRNA expression levels of proteasomal genes Psma3, Psmb5, and Psmc6 in several organs of rats. Rats were treated with metcarbatone, etcarbatone, glutapyrone, styrylcarbatone, AV-153…

glutapironDihydropyridinesProteasome Endopeptidase Complexetcarbatoneporemećena proteasomska funkcijaimpaired proteasomal functionsproteasome subunitsToxicologyPSMA3metkarbatonKidneyNeuroprotectionPSMC6glutapyroneAV-153-NaAV-153-Ca; AV-153-Na; etcarbatone; gene expression; glutapyrone; impaired proteasomal functions; metcarbatone; pharmacological activities; proteasome subunits; styrylcarbatone; ubiquitin-proteasome systemAV-153-Ca; AV-153-Na; etkarbaton; glutapiron; metkarbaton; stirilkarbaton; poremećena proteasomska funkcija; proteasomske podjedinice; ubikvitin-proteasomski sustavGene expressionAnimalsstyrylcarbatoneRNA MessengerGeneChemistryPublic Health Environmental and Occupational HealthPSMB5Cell biologyproteasomske podjediniceRatsProteostasisProteasomeubikvitin-proteasomski sustavstirilkarbatongene expressionOriginal Articlepharmacological activitiesAV-153-Caubiquitin-proteasome systemmetcarbatoneetkarbatonArchives of Industrial Hygiene and Toxicology
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