Search results for "SPECKLE-TRACKING"

showing 3 items of 3 documents

Sex differences in anthracycline-induced cardiotoxicity: the benefits of estrogens

2019

Anthracyclines are the cornerstone for many oncologic treatments, but their cardiotoxicity has been recognized for several decades. Female subjects, especially before puberty and adolescence, or after menopause, seem to be more at increased risk, with the prognostic impact of this sex issue being less consistent compared to other cardiovascular risk factors. Several studies imply that sex differences could depend on the lack of the protective effect of sex hormones against the anthracycline-initiated damage in cardiac cells, or on differential mitochondria-related oxidative gene expression. This is also reflected by the results obtained with different diagnostic methods, such as cardiovascu…

MaleCardiac & Cardiovascular SystemsMagnetic Resonance Spectroscopyand protection from anthracycline cardiotoxicitymedicine.disease_causeBioinformaticsRisk FactorsAnthracycline cardiotoxicityGender differenceGender differencesAnthracyclinesGonadal Steroid Hormones1102 Cardiorespiratory Medicine and HaematologyAMERICAN SOCIETYCardioprotectionSex CharacteristicsHeartPrognosisMitochondriaMenopauseEchocardiographyReperfusion InjuryHEART-FAILUREAnthracycline cardiotoxicity; Gender differences; Pathophysiology monitoring and protection from anthracycline cardiotoxicity; Anthracyclines; Biomarkers; Cardiotonic Agents; Cardiotoxicity; Echocardiography; Female; Gonadal Steroid Hormones; Heart; Heart Failure; Humans; Magnetic Resonance Spectroscopy; Male; Mitochondria; Nuclear Medicine; Oxidative Stress; Prognosis; Reperfusion Injury; Risk Factors; Sex CharacteristicsFemaleCardiology and Cardiovascular MedicineLife Sciences & BiomedicinePOSITION PAPERCARDIAC DYSFUNCTIONCardiotonic AgentsAnthracyclineSPECKLE-TRACKINGIschemiaDRUG CARDIOTOXICITYPathophysiologymedicineHumansCHILDHOOD-CANCER SURVIVORSBREAST-CANCERPathophysiology monitoring and protection from anthracycline cardiotoxicityHeart FailureCardiotoxicityScience & Technologybusiness.industryWORKING GROUPmedicine.diseaseCardiotoxicityOxidative StressmonitoringCardiovascular System & HematologyHeart failureCardiovascular System & CardiologyRISK-FACTORSNuclear MedicinebusinessOxidative stressAnthracycline cardiotoxicity; Gender differences; Pathophysiology monitoring and protection from anthracycline cardiotoxicityBiomarkersHormone
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Towards modern understanding of the Achilles tendon properties in human movement research

2023

The Achilles tendon (AT) is the strongest tendon in humans, yet it often suffers from injury. The mechanical properties of the AT afford efficient movement, power amplification and power attenuation during locomotor tasks. The properties and the unique structure of the AT as a common tendon for three muscles have been studied frequently in humans using in vivo methods since 1990's. As a part of the celebration of 50 years history of the International Society of Biomechanics, this paper reviews the history of the AT research focusing on its mechanical properties in humans. The questions addressed are: What are the most important mechanical properties of the Achilles tendon, how are they stud…

TechnologySPECKLE-TRACKINGBiomedical EngineeringBiophysicsISOMETRIC PLANTARFLEXIONDIFFERENTIAL STRAIN PATTERNSLOAD-DISPLACEMENT PROPERTIESjänteetELASTIC PROPERTIESstressstiffnessEngineeringYoung 's modulusstrainjäykkyysOrthopedics and Sports MedicineTRICEPS SURAE APONEUROSISin vivo -menetelmäEngineering BiomedicalIN-VIVOrasitusfyysiset ominaisuudetScience & TechnologyQUANTITATIVE ASSESSMENTRehabilitationyoung’s modulusHUMAN GASTROCNEMIUS-MUSCLEMECHANICAL-PROPERTIEShysteresiskantajännebiomekaniikkaLife Sciences & Biomedicine
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Modeling Right Ventricle Failure After Continuous Flow Left Ventricular Assist Device: A Biventricular Finite-Element and Lumped-Parameter Analysis

2017

The risk of right ventricle (RV) failure remains a major contraindication for continuous-flow left ventricular assist device (CF-LVAD) implantation in patients with heart failure. It is therefore critical to identify the patients who will benefit from early intervention to avoid adverse outcomes. We sought to advance the computational modeling description of the mechanisms underlying RV failure in LVAD-supported patients. RV failure was studied by computational modeling of hemodynamic and cardiac mechanics using lumped-parameter and biventricular finite element (FE) analysis. Findings were validated by comparison of bi-dimensional speckle-tracking echocardiographic strain assessment of the …

MaleCardiac CatheterizationCardiac outputVentricular Dysfunction Rightmedicine.medical_treatmentHemodynamicsSpeckle tracking echocardiography02 engineering and technology030204 cardiovascular system & hematologySeverity of Illness IndexRight ventricular failure Left ventricular assist device Speckle-tracking echocardiography Lumped-parameter Finite-element analysis.Ventricular Function LeftVentricular Dysfunction Left0302 clinical medicineRisk FactorsMedicineModels CardiovascularMiddle AgedTreatment Outcomemedicine.anatomical_structureEchocardiographyCardiologyFemaleCardiology and Cardiovascular MedicineAdultmedicine.medical_specialtyFinite Element Analysis0206 medical engineeringBiomedical EngineeringProsthesis DesignProsthesis Implantation03 medical and health sciencesInternal medicineSettore ING-IND/12 - Misure Meccaniche E TermicheHumansComputer SimulationInterventricular septumContraindicationRetrospective StudiesHeart Failurebusiness.industryHemodynamicsmedicine.disease020601 biomedical engineeringVentricleVentricular assist deviceHeart failureVentricular Function RightHeart-Assist DevicesbusinessCardiovascular Engineering and Technology
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