Search results for "SSH"
showing 6 items of 46 documents
Pyrgomorphid grasshoppers of the genus Phymateus contain species-specific decapeptides of the AKH/RPCH family regulating lipid-mobilization during fl…
1996
. Using heterologous and conspecific bioassays, two peptides have been isolated from methanolic extracts of corpora cardiaca from the pyrgomorphid grasshopper Phymateus morbillosus L.The structures of both peptides were elucidated by a combination of Edman degradation, after deblocking the N-terminal pyroglutamic acid residue, and mass spectrometric techniques.One peptide is an octapeptide (pGlu-Leu-Asn-Phe-Ser-Thr-Gly-TrpNH2) which also occurs in other insects and is code-named Scg-AKH-II.The second peptide is a novel decapeptide member of the AKH/RPCH family (pGlu-Leu-Asn-Phe-Thr-Pro-Asn-Trp-Gly-SerNH2 code-named here Phm-AKH.It is the first example of a different peptide in the same genu…
Modeling Vaccine Allocations in the COVID-19 Pandemic: A Case Study in Australia
2020
Timely allocation and distribution of COVID-19 vaccines on a large scale is a highly complex, dynamic, and context-specific task. The focus of this research on optimizing vaccine allocation is on the downstream part of a COVID-19 vaccine supply chain. Previous research on vaccine supply chains and pandemic supply chains has not fully incorporated the multitude of factors and underlying constraints affecting a vaccine supply chain which can be optimized to mitigate the risk of infection. An effective model is needed to conceptualize the process of the downstream vaccine supply chain to ensure efficient coordination and timely distribution of vaccines to the population. This paper develops a …
Scatter search for an uncapacitated p-hub median problem
2015
Scatter search is a population-based method that has been shown to yield high-quality outcomes for combinatorial optimization problems. It uses strategies for combining solution vectors that have proved effective in a variety of problem settings. In this paper, we present a scatter search implementation for an NP -hard variant of the classic p-hub median problem. Specifically, we tackle the uncapacitated r-allocation p-hub median problem, which consists of minimizing the cost of transporting the traffics between nodes of a network through special facilities that act as transshipment points. This problem has a significant number of applications in practice, such as the design of transportati…
Control of ovarian steroidogenesis in insects: A locust neurohormone is active in vitro on blowfly ovaries
2009
0016-6480 doi: DOI: 10.1016/j.ygcen.2009.04.034; Ovarian steroidogenesis controlling insect reproduction is mainly regulated by brain gonadotropins liberated from corpora cardiaca (CC). Till now, different neurohormones have been identified in two insect groups only, locusts and mosquitoes, and it is unknown whether they could be active in other insects. In order to complete previous observations on the control of ovarian steroidogenesis in the blowfly, Phormia regina, we examined whether neuropeptides isolated from locust CC have an effect in vitro on ovarian steroidogenesis in our dipteran model. Our experiments showed that crude extracts from locust CC efficiently stimulated steroidogene…
The toxic and lethal effects of the trehalase inhibitor trehazolin in locusts are caused by hypoglycaemia
2003
SUMMARY The main blood sugar of locusts is trehalose, which is hydrolysed to two glucose units by trehalase. Homogenates of locust flight muscles are rich in trehalase activity, which is bound to membranes. A minor fraction of trehalase is in an overt form while the remainder is latent, i.e. active only after impairing membrane integrity. Trehazolin, an antibiotic pseudosaccharide,inhibits locust flight muscle trehalase with apparent Ki-and EC50 values of 10–8 mol l–1and 10–7 mol l–1, respectively. Trehazolin is insecticidal: 50 μg injected into locusts completely and selectively blocked the overt form of muscle trehalase (with little effect on latent activity) and killed 50% of the insects…
La circulation des termes dans le discours médiatique : peut-on informer sans déformer ?
2016
Media diversification and information superhighways that have become faster and faster have boosted the circulation of economic terms in the popular press, along with the interaction between editorial contents targeted at the general population, which are similar in nature. This twin phenomenon of circulation and interaction was highlighted in a contrastive study of the way the German and the French press managed the euro crisis between 2011 and 2013: articles devoted to the debt of countries that are going through hard economic times require expert knowledge, but also resort to popularization strategies that show multi-level interdiscursivity.