Search results for "STABILITY"

ADI schemes for valuing European options under the Bates model

2018

This paper is concerned with the adaptation of alternating direction implicit (ADI) time discretization schemes for the numerical solution of partial integro-differential equations (PIDEs) with application to the Bates model in finance. Three different adaptations are formulated and their (von Neumann) stability is analyzed. Ample numerical experiments are provided for the Bates PIDE, illustrating the actual stability and convergence behaviour of the three adaptations. peerReviewed

Stabilność polityczna i personalna władz w warunkach alternacji i ciągłości rządów

2017

Celem rozdziału jest analiza stabilności polskiej sceny politycznej w wymiarze politycznym i personalnym. Przejścia i rozłamy w klubach parlamentarnych oraz zmiany w ramach gabinetów rządowych w trakcie V, VI i VII kadencji Sejmu poddane zostały analizie ilościowej i jakościowej. Pozwoliła ona sformułować wnioski o stabilności struktur władzy ustawodawczej i wykonawczej. Analizie poddano okres 10 lat, obejmujący trzy kadencje Sejmu oraz pięć gabinetów rządowych. Głównym problemem badawczym jest określenie, na ile zmiany w politycznym i personalnym składzie organów władzy wykonawczej i ustawodawczej odzwierciedlają polityczną stabilność całego systemu politycznego. Pod uwagę wzięto trzy kade…

FORMAZIONE DI PATTERN PER IL PROCESSO DELL'ELETTRODEPOSIZIONE IN MODELLI DI TIPO REAZIONE-DIFFUSIONE

2014

Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis

2022

Simple Summary International guidelines recommend universal screening of endometrial carcinoma patients for Lynch syndrome, a hereditary cancer predisposition syndrome. Screening is based on mismatch repair protein immunohistochemistry and reflex MLH1 methylation analysis to exclude the likely sporadic cases of MMR deficiency. As sporadic MLH1 protein loss is common in endometrial carcinoma, the ability to target methylation testing would save efforts and costs. We discovered that limiting methylation testing to patients under 65 years would have significantly reduced the testing effort while maintaining a low false negative rate for MLH1-LS detection (0% and 3% in our clinic and registry-b…

On the high-pressure phase stability and elastic properties ofβ-titanium alloys

2017

We have studied the compressibility and stability of different β-titanium alloys at high pressure, including binary Ti–Mo, Ti–24Nb–4Zr–8Sn (Ti2448) and Ti–36Nb–2Ta–0.3O (gum metal). We observed stability of the β phase in these alloys to 40 GPa, well into the ω phase region in the P–T diagram of pure titanium. Gum metal was pressurised above 70 GPa and forms a phase with a crystal structure similar to the η phase of pure Ti. The bulk moduli determined for the different alloys range from 97  ±  3 GPa (Ti2448) to 124  ±  6 GPa (Ti–16.8Mo–0.13O).

Assessment of Physical and Chemical Stability of Different Magnesium Compounds in Tablets

2020

Modern lifestyle, excessive chemicalization of agricultural products, excessive processing and refining of food, cause a decrease in daily intake of magnesium, cation with an extremely important role in prevention and treatment of many diseases. As a result, there arises the need for extra magnesium intake in the form of dietary supplements. In this study were evaluated the physical and chemical stability of magnesium-containing tablets, depending on the active compound and the excipients used. Magnesium tablets in the form of orotate, lactate, citrate, oxide and hydroxide were taken into study and physical and chemical stability were observed over the validity period, at 6 and at 12 month…

Heat-sensitive UV-Vis measurements for Phytochrome

2016

Fytokromit ovat punaista valoa aistivia proteiineja, jotka säätelevät suurta joukkoa solun toimintoja kasvi-, bakteeri- ja sienisoluissa. Nämä valoaktiiviset proteiinit muuntavat konformaatiotaan palautuvasti aktiivisen (Pfr) ja inaktiivisen (Pr) tilan välillä. Fytokromien aminohappojen väliset heikot vuorovaikutukset - etenkin vetysidokset - vaikuttavat lopulta laskostumiseen ja proteiinin lämpöstabiiliuteen. Fytokromit esiintyvät homodimeerisinä rakenteina, joiden monomeerit koostuvat useista domeeneista. Nämä jakautuvat N- terminaaliseen valosensitiiviseen moduuliin (PSM) ja C-terminaaliseen OutPut moduliin (OPM). PSM koostuu kolmesta domeenista (PAS-GAF ja PHY). Tässä työssä tutkittiin …

The Interconnecting Hairpin Extension "Arm": An Essential Allosteric Element of Phytochrome Activity

2023

In red-light sensing phytochromes, isomerization of the bilin chromophore triggers structural and dynamic changes across multiple domains, ultimately leading to control of the output module (OPM) activity. In between, a hairpin structure, "arm", extends from an interconnecting domain to the chromophore region. Here, by removing this protein segment in a bacteriophytochrome from Deinococcus radiodurans (DrBphP), we show that the arm is crucial for signal transduction. Crystallographic, spectroscopic, and biochemical data indicate that this variant maintains the properties of DrBphP in the resting state. Spectroscopic data also reveal that the armless systems maintain the ability to respond t…

Dynamic regimes of cyclotron instability in the afterglow mode of minimum-B electron cyclotron resonance ion source plasma

2016

The paper is concerned with the dynamic regimes of cyclotron instabilities in non-equilibrium plasma of a minimum-B electron cyclotron resonance ion source operated in pulsed mode. The instability appears in decaying ion source plasma shortly (1–10 ms) after switching off the microwave radiation of the klystron, and manifests itself in the form of powerful pulses of electromagnetic emission associated with precipitation of high-energy electrons along the magnetic field lines. Recently it was shown that this plasma instability causes perturbations of the extracted ion current, which limits the performance of the ion source and generates strong bursts of bremsstrahlung emission. In this artic…

Plasmid Viability Depends on the Ecological Setting of Hosts within a Multiplasmid Community

2022

Plasmids are extrachromosomal genetic elements, some of which disperse horizontally between different strains and species of bacteria. They are a major factor in the dissemination of virulence factors and antibiotic resistance. Understanding the ecology of plasmids has a notable anthropocentric value, and therefore, the interactions between bacterial hosts and individual plasmids have been studied in detail. However, bacterial systems often carry multiple genetically distinct plasmids, but dynamics within these multiplasmid communities have remained unstudied. Here, we set to investigate the survival of 11 mobilizable or conjugative plasmids under five different conditions where the hosts h…