Search results for "STAGE"
showing 10 items of 1393 documents
Bayesian two-stage regression with parametric heteroscedasticity
2008
In this paper, we expand Kleibergen and Zivot's (2003) Bayesian two-stage (B2S) model by allowing for unequal variances. Our choice for modeling heteroscedasticity is a fully Bayesian parametric approach. As an application, we present a cross-country Cobb–Douglas production function estimation.
A systematic review on external ear melanoma
2014
Summary Background External ear melanoma accounts for only 1% of all cutaneous melanomas, and data on its optimal management and prognosis are limited. Aim We aim to review the literature on external ear melanoma to guide surgeons in the treatment of this uncommon and peculiar pathology. Materials and methods A systematic review of English language studies on ear melanoma published from 1993 to 2013 was performed using the PubMed electronic database. Data on epidemiology, oncological treatment (tumor resection and regional lymph nodes management), and reconstruction were extrapolated from selected papers. Results The total number of patients was 858 (30 studies). The helix was the most comm…
Multi-directional vs. mono-directional multi-step strategies for single point incremental forming of non-axisymmetric components
2020
Abstract Multi Stage approach is used in Single Point Incremental Forming (SPIF) to overcome one of the main forming limitations, namely the maximum wall angle, characterizing the single stage process. In this paper, different multi-path strategies for the production of parts with flat edges are considered in order to evaluate the best solution in terms of feasibility and geometrical accuracy of the final part: A) mono-directional incremental draw angle; B) mono-directional incremental draw angle with increasing part side; C) Multi-directional approach with non-horizontal path planes. Strain evaluation by means of CGA (Circular Grid Analysis) and defect analysis have been carried out in ord…
A Two-Stage Reconstruction of Microstructures with Arbitrarily Shaped Inclusions
2020
The main goal of our research is to develop an effective method with a wide range of applications for the statistical reconstruction of heterogeneous microstructures with compact inclusions of any shape, such as highly irregular grains. The devised approach uses multi-scale extended entropic descriptors (ED) that quantify the degree of spatial non-uniformity of configurations of finite-sized objects. This technique is an innovative development of previously elaborated entropy methods for statistical reconstruction. Here, we discuss the two-dimensional case, but this method can be generalized into three dimensions. At the first stage, the developed procedure creates a set of black synthetic …
Amidst Uncertainty–or Not? : Decision-Making in Early-Stage Software Startups
2019
It is commonly claimed that the initial stages of any startup business are dominated by continuous, extended uncertainty, in an environment that has even been described as chaotic. Consequently, decisions are made in uncertain circumstances, so making the right decision is crucial to successful business. However, little currently exists in the way of empirical studies into this supposed uncertainty. In this paper, we study decision-making in early-stage software startups by means of a single, in-depth case study. Based on our data, we argue that software startups do not work in a chaotic environment, nor are they characterized by unique uncertainty unlike that experienced by other firms. pe…
A preliminary study of agility in business and production - Cases of early-stage hardware startups
2018
[Context] Advancement in technologies, popularity of small-batch manufacturing and the recent trend of investing in hardware startups are among the factors leading to the rise of hardware startups nowadays. It is essential for hardware startups, companies that involve both software and hardware development, to be not only agile to develop their business but also efficient to develop the right products. [Objective] We investigate how hardware startups achieve agility when developing their products in early stages. [Methods] A qualitative research is conducted with data from 20 hardware startups. [Result] Preliminary results show that agile development is known to hardware entrepreneurs, howe…
Hyaluronic acid-based two-stage medical therapy to unfold the aged face: The centrifugal approach
2020
Background: Facial aging is a multifactorial process characterized by structural changes to the dermis and ligaments, lipoatrophy in the fat pads and hypodermis, remodeling of the bony skeleton, change in muscle tonicity and tissue descent. Aims: The purpose of this study is to evaluate the efficacy of a hyaluronic acid-based treatment for the aging face that addresses all its causes in a caudal to cranial and medial to lateral direction: the centrifugal technique. Methods: Between March 2015 and January 2018, 187 patients were treated with a high G’ hyaluronic acid in two sessions, one/two weeks apart, to improve signs of facial aging, starting from the lower centrofacial area and progress…
Fascioliasis and other plant-borne trematode zoonoses
2005
Fascioliasis and other food-borne trematodiases are included in the list of important helminthiases with a great impact on human development. Six plant-borne trematode species have been found to affect humans: Fasciola hepatica, Fasciola gigantica and Fasciolopsis buski (Fasciolidae), Gastrodiscoides hominis (Gastrodiscidae), Watsonius watsoni and Fischoederius elongatus (Paramphistomidae). Whereas F. hepatica and F. gigantica are hepatic, the other four species are intestinal parasites. The fasciolids and the gastrodiscid cause important zoonoses distributed throughout many countries, while W. watsoni and F. elongatus have been only accidentally detected in humans. Present climate and glob…
Fertility outcome after radical vaginal trachelectomy: a prospective study of 212 patients.
2011
ObjectiveFor treatment in patients with early-stage cervical cancer, radical vaginal trachelectomy (RVT) as a fertility-preserving surgery can be put on a par with radical hysterectomy as to oncologic safety. Our aim was to investigate the fertility concerns and outcome.MethodsProspective collection of fertility data of patients treated with RVT. The data were collected on personal communication, by telephone, or e-mail correspondence. Descriptive statistical analysis was performed.ResultsBetween March 2005 and April 2010, 212 patients were followed up after RVT. Only 76 patients (35.9%) were seeking parenthood currently. Sixty pregnancies occurred in 50 women. Five patients (8.3%) had firs…
Fetun-A and end stage renal disease: correlations with haemodialytic single session and genotype
2011
Several studies showed that Fetuin-a is an extracellular calcium-regulatory protein acting as a potent inhibitor of calcium-phosphate precipitation, involved also in bone metabolism because of its high affinity for hydroxyapatite. The aim of this study is to evaluate the serum Fetuin-A levels in patients with chronic renal failure before and after a single session of dialysis and to investigate the correlation between protein serum concentrations and T256S genotype. Our results show that serum Fetuin- A levels decrease 4 hours after haemodialysis treatment and a significant correlation between 256SS homozygote and serum protein levels. Ectopic calcification and particularly intravascular ca…