Search results for "STAGE"
showing 10 items of 1393 documents
Hepatic vein tumor thrombosis in patients with hepatocellular carcinoma: Prevalence and clinical significance.
2021
Abstract Background There is strong evidence that portal vein tumor thrombosis (PVTT) is associated with poor survival in patients with hepatocellular carcinoma (HCC). However, data regarding the clinical significance of hepatic vein tumor thrombosis (HVTT) is rare, particularly in Western patients. Objective To determine the HVTT prevalence in a Western patient population and its impact on survival. Methods We included 1310 patients with HCC treated in our tertiary referral center between January 2005 and December 2016. HVTT and PVTT were diagnosed with contrast‐enhanced cross‐sectional imaging. Overall survival (OS) was calculated starting from the initial HCC diagnosis, and in a second s…
A nanomaterial-based breath test for distinguishing gastric cancer from benign gastric conditions
2013
Background: Upper digestive endoscopy with biopsy and histopathological evaluation of the biopsy material is the standard method for diagnosing gastric cancer (GC). However, this procedure may not be widely available for screening in the developing world, whereas in developed countries endoscopy is frequently used without major clinical gain. There is a high demand for a simple and non-invasive test for selecting the individuals at increased risk that should undergo the endoscopic examination. Here, we studied the feasibility of a nanomaterial-based breath test for identifying GC among patients with gastric complaints. Methods: Alveolar exhaled breath samples from 130 patients with gastric …
Conservation, Spillover and Gene Flow within a Network of Northern European Marine Protected Areas
2013
Published version of an article in the journal: PLoS ONE. Also available from the publisher at: http://dx.doi.org/10.1371/journal.pone.0073388 Open access To ensure that marine protected areas (MPAs) benefit conservation and fisheries, the effectiveness of MPA designs has to be evaluated in field studies. Using an interdisciplinary approach, we empirically assessed the design of a network of northern MPAs where fishing for European lobster (Homarus gammarus) is prohibited. First, we demonstrate a high level of residency and survival (50%) for almost a year (363 days) within MPAs, despite small MPA sizes (0.5-1 km2). Second, we demonstrate limited export (4.7%) of lobsters tagged within MPAs…
New Evidence of MIS 3 Relative Sea Level Changes from the Messina Strait, Calabria (Italy)
2021
Investigation of sea-level positions during the highly-dynamic Marine Isotope Stage 3 (MIS 3: 29–61 kyrs BP) proves difficult because: (i) in stable and subsiding areas, coeval coastal sediments are currently submerged at depths of few to several tens of meters below the present sea level
Paleolakes in the Gobi region of southern Mongolia
2018
Abstract Numerous lakes and remnants of paleolakes exist in western and southern Mongolia. For six basins in the area, detailed geomorphological maps were compiled, based on extensive field studies and remote sensing datasets. Several phases of high and low lake levels were reconstructed and dated by radiocarbon and optically stimulated luminescence. During the marine isotope stage (MIS) 6 lakes in southern and western Mongolia mostly disappeared. In contrast, large paleolakes existed during the last interglacial (MIS 5e) and lasted probably until the beginning of the last glacial. These huge lakes were caused by a strong East Asian summer monsoon, which reached southern and even western Mo…
The ELSA-Vegetation-Stack: Reconstruction of Landscape Evolution Zones (LEZ) from laminated Eifel maar sediments of the last 60,000 years
2016
Abstract Laminated sediment records from several maar lakes and dry maar lakes of the Eifel (Germany) reveal the history of climate, weather, environment, vegetation, and land use in central Europe during the last 60,000 years. The time series of the last 30,000 years is based on a continuous varve counted chronology, the MIS3 section is tuned to the Greenland ice — both with independent age control from 14C dates. Total carbon, pollen and plant macrofossils are used to synthesize a vegetation-stack, which is used together with the stacks from seasonal varve formation, flood layers, eolian dust content and volcanic tephra layers to define Landscape Evolution Zones (LEZ). LEZ 1 encompasses t…
Paleoenvironmental context of the early Neanderthals of Poggetti Vecchi for the late middle Pleistocene of Central Italy
2017
AbstractWork on thermal pools at Poggetti Vecchi in Grosseto, Italy, exposed an up to 3-meter-thick succession of seven sedimentary units. Unit 2 in the lower portion of the succession contained vertebrate bones, mostly of the straight-tusked elephant, Palaeoloxodon antiquus, commingled with stone, bone, and wooden tools. Thermal carbonates overlying Unit 2 are radiometrically dated to the latter part of the middle Pleistocene. This time span indicates that early Neanderthals produced the human artifacts from Poggetti Vecchi. The elephant bones belong to seven individuals of different ages. Sedimentary facies analysis and paleoecological evidence suggest a narrow lacustrine-palustrine embay…
Liquefaction and re-liquefaction of sediments induced by uneven loading and glacigenic earthquakes: Implications of results from the Latvian Baltic S…
2021
Abstract Seven internally-deformed layers were recognised in the shallow marine bay sediments deposited during mid Marine Isotope Stage 2 along the Latvian Baltic Sea coast bluff at Baltmuiža. Detailed sedimentological analyses of these deformed layers indicate that liquefaction was responsible for the development of soft-sediment deformation structures (SSDS) including injection structures, load casts, flame structures and pseudonodules. Traces of both initial liquefaction and re-liquefaction were recognised within at least four of the seven layers with SSDS (two different generations of pseudonodules and injection structures, clastic injection pipes, disrupted load casts). This is a uniqu…
Late Pleistocene (MIS 3-4) climate inferred from micromammal communities and δ18O of rodents from Les Pradelles, France.
2013
The middle Paleolithic stratigraphic sequence of Les Pradelles (Charente, France) spans from the end of Marine Isotope Stage (MIS) 4 until the middle of MIS 3. Micromammal remains are present in all the stratigraphic levels, offering a rare opportunity to address the questions of both environmental and climatic fluctuations throughout this period. Climate modes were studied through the taphonomy, biodiversity and oxygen isotope compositions of phosphate (δ18O p ) from 66 samples of rodent tooth enamel. The δ18O p values from the lower sedimentary levels provide summer mean air temperatures of 19 ± 2°C (level 2/1) and of 16 ± 2°C (levels 2A, 2B and 4A). Within the middle of sequence (level 4…
Late Quaternary environments in the Gobi Desert of Mongolia: Vegetation, hydrological, and palaeoclimate evolution
2019
Abstract Considerable efforts have been devoted to decipher the late Quaternary moisture and thermal evolution of arid central Asia. However, disparate interpretations still exist concerning different proxies. The spatial and temporal heterogeneities have inhibited a holistic understanding of general patterns and underlying mechanisms. To address these issues, two parallel cores (ONW I, 6.00 m; ONW II, 13.35 m) were retrieved in the Gobi Desert of Mongolia from lake Orog Nuur. Multidisciplinary investigations including geomorphological mapping, radiocarbon dating, sedimentological, palynological and ostracod analyses enabled us to gain a comprehensive dataset for vegetation development and …