Search results for "STRESS"
showing 10 items of 6278 documents
Emotional Distress of Patients at End-of-Life and Their Caregivers: Interrelation and Predictors
2018
Background: Patients at the end of life and their families experience a strong emotional impact. The well-being of these patients and that of their family caregiver are related. Aim: To study the variables related with the emotional well-being of patients with and without cognitive impairment at the end of life and that of their primary family caregivers. Design: Cross- sectional study. Participants: Data was collected from 202 patients at the end of life with different diagnosis (COPD, cancer, and frail elderly) as well as from their respective 202 primary family caregivers. Results: Structural equation models indicated that the emotional state of the patients was best predicted by their f…
Psychosocial stress, catecholamines, and essential fatty acid metabolism in rats.
1994
To examine the effects of psychosocial stress and the "stress hormone," epinephrine, on essential fatty acid metabolism in rats, two studies were conducted. In the first, the effects of four weeks of (i) social isolation and (ii) group housing (control) on liver microsomal delta 6 and delta 5 n-6 desaturase activity were studied in group-reared male normotensive (Wistar Kyoto) and spontaneously hypertensive (SHR) rats (n = 5/group). The second study examined the effects of acute ip epinephrine (0.0, 1.0, 2.0, and 4.0 mg/kg) 6 hr prior to and following an ig dose (4 g/kg) of safflower oil (rich in 18:2n-6, LA) on plasma and liver LA, 20:4n-6 (AA), and LA/AA ratios in adult essential fatty ac…
Oxidative stress induces the expression of the major histocompatibility complex in murine tumor cells.
2001
The effect of t-butyl hydroperoxide (t-BOOH) on the induction of the Major Histocompatibility Complex (MHC) class I genes has been studied in two cell clones (B9 and G2) of the methylcholanthrene-induced murine fibrosarcoma GR9. These two clones were selected based on their different biological and biochemical behavior specially related to their tumor induction capability when injected into a BALB/c mouse. t-BOOH (0.125 mM) induced the expression of H-2 molecules in both cell clones. In B9 cell clone, in which MHC basal expression is very low or absent, t-BOOH significantly induced H-2Kd, H-2Dd and H-2Ld molecules. In G2 cell clone the expression of MHC class I genes was also enhanced by th…
Shear resistance analytical evaluation for RC beams with transverse reinforcement with two different inclinations
2020
An analysis-oriented mechanical model for shear strength evaluation of Reinforced Concrete (RC) beams with transverse reinforcement with two different inclinations, which required a numerical analysis, is turned into a design-oriented analytical model that can easily be utilized for practical purposes. The model assessed the shear resistance, according to the “lower-bound solution”, employing a numerical procedure that maximizes the element shear strength varying the stresses in the two sets of transverse reinforcement and the magnitude and inclination of the web concrete compressive stress field. The model is formulated with the aim of representing an extension of Eurocode 2 framework to R…
Empirical Analyses of Networks in Finance
2018
Abstract The recent global financial crisis has triggered a huge interest in the use of network concepts and network tools to better understand how instabilities can propagate through the financial system. The literature is today quite vast, covering both theoretical and empirical aspects. This review concentrates on empirical work, and associated methodologies, concerned with the evaluation of the fragility and resilience of financial and credit markets. The first part of the review examines the literature on systemic risk that arise from banks mutual exposures. These exposures stem primarily from interbank lending and derivative positions, but also, indirectly, from common holdings of oth…
Corporate Distress and Restructuring with Macroeconomic Fluctuations: The Cases of GM and Ford
2011
Traditional methods for evaluating corporate credit risk rarely consider the impact of the macro economy on corporate value and performance. We argue that lenders and management can obtain valuable information about the need for and approach to restructuring by decomposing default predictions into intrinsic and macroeconomic factors. We apply a method previously used for measuring macroeconomic exposures on default predictions in order to filter out macroeconomic factors. In this paper the method is applied on an analysis of the Z-scores for GM and Ford for the period 1996-2005. The macro-economy has affected the two firms in different ways with implications for managements and creditors ap…
Uneven economic burden of non-communicable diseases among Indian households: A comparative analysis
2021
Background Non-communicable diseases (NCDs) are the leading global cause of death and disproportionately concentrate among those living in low-income and middle-income countries. However, its economic impact on households remains less well known in the Indian context. This study aims to assess the economic impact of NCDs in terms of out-of-pocket expenditure (OOPE) and its catastrophic impact on NCDs affected households in India. Materials and methods Data were collected from the 75th round of the National Sample Survey Office, Government of India, conducted in the year 2017–18. This is the latest round of data available on health, which constitutes a sample of 113,823 households. The coll…
Virtual simulation of an osseointegrated trans-humeral prosthesis: A falling scenario
2018
Abstract Introduction Traditional prosthetic solutions expose the amputee to numerous problems that limit his ability to safely perform the normal activities of daily life. In order to eliminate the problems related to the use of the traditional prosthesis with socket, a new technique was developed for fixing the prosthesis to the amputees based on the principle of osseointegration. The aim of this paper is to study and analyze the stress distribution on the interface between a trans-humeral osseointegrated prosthetic implant and the residual bone, identifying the most stressed areas and thus foreseeing possible failure phenomena of the entire prosthetic system and, after, to compare the st…
Abrupt elastic-to-plastic transition in pentagonal nanowires under bending
2019
MD modeling and calculations were supported by Russian Science Foundation project grant 18-19-00645 “Adhesion of polymer-based soft materials: from liquid to solid”; mechanical testing and FEM simulations were supported by Estonian Research Council projects PUT1689 and PUT1372.
Stressing sequence of steel cable-stayed bridges built by cantilevering
2015
The construction of cable-stayed bridges by cantilevering implies several changes of geometry, stress and strain patterns during the assemblage of segments. The main target to be satisfied in the construction process is the achievement of the required final geometry and of a convenient state of stress for self-weight and sustained loads. The sequence of stay stressing and the values of prestressing forces at each stage of segment assembling have the main role for reaching the desired result of design, due to the large redundancy of cable-stayed structures.Among the different procedures proposed in the literature for initial cable force determination, the Partial Elastic Scheme (PES) Method …