Search results for "SUBSTANCES"

showing 10 items of 1122 documents

Essential Enabling Technologies

2016

The previous chapter contained presentations of several relevant collaboration methods. Section 3.1 indicated that the evolution in e-collaboration was associated with a number of technological breakthroughs.

Decision support systemBiometric systemComputer sciencebusiness.industrySection (typography)020206 networking & telecommunicationsCloud computingmacromolecular substances02 engineering and technologyData sciencehumanitiesBusiness intelligence0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingbusinessMobile device
researchProduct

Thiocarbamate-Linked Polysulfonate–Peptide Conjugates As Selective Hepatocyte Growth Factor Receptor Binders

2014

The capacity of many proteins to interact with natural or synthetic polyanions has been exploited for modulating their biological action. However, the polydispersity of these macromolecular polyanions as well as their poor specificity is a severe limitation to their use as drugs. An emerging trend in this field is the synthesis of homogeneous and well-defined polyanion–peptide conjugates, which act as bivalent ligands, with the peptide part bringing the selectivity of the scaffold. Alternately, this strategy can be used for improving the binding of short peptides to polyanion-binding protein targets. This work describes the design and first synthesis of homogeneous polysulfonate–peptide con…

DendrimersBiomedical EngineeringPharmaceutical ScienceBioengineeringPeptidemacromolecular substancesPlasma protein bindingArticleReceptor tyrosine kinaseSubstrate SpecificityStructure-Activity RelationshipThiocarbamatesmedicineHumansStructure–activity relationshipPharmacologychemistry.chemical_classificationDose-Response Relationship DrugMolecular StructurebiologyHepatocyte Growth FactorChemistryOrganic Chemistrytechnology industry and agricultureProto-Oncogene Proteins c-metProtein Structure TertiaryThiocarbamateBiochemistryHepatocyte Growth Factor ReceptorProto-Oncogene Proteins c-metbiology.proteinHepatocyte growth factorSulfonic AcidsPeptidesProtein BindingBiotechnologymedicine.drugBioconjugate Chemistry
researchProduct

Development of an ICP-IDMS method for accurate routine analyses of toxic heavy metals in polyolefins and comparison with results by TI-IDMS

2000

An inductively coupled plasma isotope dilution mass spectrometric (ICP-IDMS) method was developed as a suitable method - with respect to its sensitivity, precision, accuracy, and time-consumption - for the analysis of toxic heavy metal traces (Pb, Cd, Cr, and Hg) in polyolefins. Results for Pb, Cd, and Cr were compared with those obtained by thermal ionization isotope dilution mass spectrometry (TI-IDMS), which was used as a reference method. Because of its high first ionization potential and its high volatility mercury could not be determined by TI-IDMS. A multi-element spike solution, containing isotopically enriched 206Pb, 116Cd, 53Cr, and 201Hg, was used for the isotope dilution step. D…

Detection limitIsotopeChemistryAnalytical chemistryThermal ionizationchemistry.chemical_elementAlkenesIsotope dilutionMass spectrometrySensitivity and SpecificityBiochemistryHazardous SubstancesMass SpectrometryMercury (element)IsotopesPolyethyleneMetals HeavyInductively coupled plasmaChemical decompositionFresenius' Journal of Analytical Chemistry
researchProduct

Combined proton NMR wideline and NMR relaxometry to study SOM-water interactions of cation-treated soils

2013

Abstract Focusing on the idea that multivalent cations affect SOM matrix and surface, we treated peat and soil samples by solutions of NaCl, CaCl2 or AlCl3. Water binding was characterized with low field 1H-NMR-relaxometry (20 MHz) and 1H wideline NMR spectroscopy (400 MHz) and compared to contact angles. From 1H wideline, we distinguished mobile water and water involved in water molecule bridges (WaMB). Large part of cation bridges (CaB) between SOM functional groups are associated with WaMB. Unexpectedly, 1H NMRrelaxometry relaxation rates suggest that cross-linking in the Al-containing peat is not stronger than that by Ca. The relation between percentage of mobile water and WaMB water in…

Dewey Decimal Classification::500 | Naturwissenschaften::550 | GeowissenschaftenDewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften BiologieDewey Decimal Classification::600 | Technik::630 | Landwirtschaft VeterinärmedizinAnalytical chemistrySoil organic matter (SOM); Low field 1H NMR relaxometry; 1H wideline NMR spectroscopy; Contact angle; Cation bridges; Water molecule bridges.TA Engineering (General). Civil engineering (General)soil organic matter (som)Low field H-1 NMR relaxometrystateContact angleNuclear magnetic resonancewater molecule bridgesddc:550ddc:630natural organic-mattercontact angleWater Science and TechnologyFluid Flow and Transfer Processeschemistry.chemical_classificationhumic substancesWater molecule bridges.Nuclear magnetic resonance spectroscopycation bridgesCation bridgemultiexponential decay datanuclear-magnetic-resonanceH-1 wideline NMR spectroscopyProton NMRWater bindingTC1-978Relaxometryuniform-penalty inversionlow field 1h nmr relaxometrySettore AGR/13 - Chimica AgrariaContext (language use)1h wideline nmr spectroscopyforest soilsCation bridgesddc:570sandy soilOrganic mattercontact-angleContact angleSoil organic matter (SOM)repellencyMechanical EngineeringHydraulic engineeringchemistrySoil waterWater molecule bridgesJournal of Hydrology and Hydromechanics
researchProduct

POLYASPARTAMIDE-POLYLACTIDE GRAFT COPOLYMERS WITH TUNABLE PROPERTIES FOR THE REALIZATION OF FLUORESCENT NANOPARTICLES FOR IMAGING

2015

Here, the synthesis and the characterization of novel amphiphilic graft copolymers with tunable properties, useful in obtaining polymeric fluorescent nanoparticles for application in imaging, are described. These copolymers are obtained by chemical conjugation of rhodamine B (RhB) moieties, polylactic acid (PLA), and O-(2-aminoethyl)-O'-methyl poly(ethylene glycol) (PEG) on α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide (PHEA). In particular, PHEA is first functionalized with RhB to obtain PHEA-RhB with a derivatization degree in RhB (DDRhB ) equal to 0.55 mol%. By varying the reaction conditions, different amounts of PLA are grafted on PHEA-RhB to obtain PHEA-RhB-PLA with DDPLA equal to 1.9, 4…

Diagnostic ImagingMaterials sciencePolymers and Plasticspolyethylene glycol (PEG)PolymersPolyestersNanoparticlemacromolecular substancesPolyethylene Glycolschemistry.chemical_compoundstomatognathic systemPolylactic acidAmphiphilePolymer chemistryPEG ratioMaterials ChemistryCopolymerRhodamine BLactic AcidPolyhydroxyethyl Methacrylateαβ-poly-(N-2-hydroxyethyl)-dl-aspartamide (PHEA)polylactic acid (PLA)nanoparticleOrganic Chemistrytechnology industry and agricultureFluorescencechemistryNanoparticlesfluorescenceEthylene glycol
researchProduct

Pneumocisternographic exploration of the posterior fossa

1958

A method previously proposed by the Author for the pneumographic visualization of the posterior fossa has been utilized for the study of several cases. Of these some are reported in this paper. The indications and the advantages of the method are discussed.

Diagnostic Imagingmedicine.medical_specialtyNeurologymedicine.diagnostic_testbusiness.industryPosterior fossaInterventional radiologymacromolecular substancesAnatomyRadiographyHumansMedicineSurgeryNeurology (clinical)NeurosurgerybusinessHeadNeuroradiologyActa Neurochirurgica
researchProduct

Pressure-induced phase transformations in mineral chalcocite, Cu2S, under hydrostatic conditions

2014

Abstract High-pressure room-temperature angle-dispersive powder X-ray diffraction measurements on Cu2S chalcocite were performed up to 30 GPa using a diamond-anvil cell, He as pressure transmitting medium and synchrotron radiation. Two first-order phase transitions were found at 3.2 and 7.4 GPa. The indexation of the powder diffraction patterns suggests three different monoclinic cells for the low-pressure chalcocite and the two high-pressure phases. Subtle changes in the X-ray diffraction patterns suggest a third pressure-induced transition above 26 GPa. Structural parameters and compressibility are discussed and compared to those reported in a previous study on Cu2S nanowires.

DiffractionPhase transitionChalcociteChemistryMechanical EngineeringMetals and AlloysAnalytical chemistryMineralogySynchrotron radiationmacromolecular substancesengineering.materialPolymorphism (materials science)Mechanics of MaterialsMaterials ChemistryCompressibilityengineeringPowder diffractionMonoclinic crystal systemJournal of Alloys and Compounds
researchProduct

AB$$_{2}$$O$$_{4}$$ Compounds at High Pressures

2014

In this chapter, we present an overview of the effects of pressure on the crystalline structure and physical properties of oxygen-based spinels and other related oxides. Recent X-ray diffraction and Raman spectroscopy studies are summarized. A brief description of pressure-driven transitions and post-spinel structures is also provided. We also compare the response to high-pressure of several spinel oxides. We conclude with an examination of elastic and magnetic properties.

DiffractionPhase transitionMaterials scienceSpinelchemistry.chemical_elementLattice vibrationmacromolecular substancesCrystal structureengineering.materialOxygensymbols.namesakeCrystallographychemistryengineeringsymbolsRaman spectroscopy
researchProduct

Effective hydrostatic limits of pressure media for high‐pressure crystallographic studies

2007

The behavior of a number of commonly used pressure media, including nitrogen, argon, 2-propanol, a 4:1 methanol–ethanol mixture, glycerol and various grades of silicone oil, has been examined by measuring the X-ray diffraction maxima from quartz single crystals loaded in a diamond-anvil cell with each of these pressure media in turn. In all cases, the onset of non-hydrostatic stresses within the medium is detectable as the broadening of the rocking curves of X-ray diffraction peaks from the single crystals. The onset of broadening of the rocking curves of quartz is detected at ∼9.8 GPa in a 4:1 mixture of methanol and ethanol and at ∼4.2 GPa in 2-propanol, essentially at the same pressures …

DiffractionShear wavesArgonhydrostatic limitschemistry.chemical_elementmacromolecular substanceshigh-pressure crystallographic studiesNitrogenGeneral Biochemistry Genetics and Molecular BiologySilicone oillaw.inventionchemistry.chemical_compoundCrystallographystomatognathic systemchemistrylawHydrostatic equilibriumGlass transitionQuartzJournal of Applied Crystallography
researchProduct

Structural Characterization of Aurophilic Gold(I) Iodide under High Pressure

2019

[EN] The effects of pressure on the crystal structure of aurophilic tetragonal gold iodide have been studied by means of powder X-ray diffraction up to 13.5 GPa. We found evidence of the onset of a phase transition at 1.5 GPa that is more significant from 3.8 GPa. The low- and high-pressure phases coexist up to 10.7 GPa. Beyond 10.7 GPa, an irreversible process of amorphization takes place. We determined the axial and bulk compressibility of the ambient-pressure tetragonal phase of gold iodide up to 3.3 GPa. This is extremely compressible with a bulk modulus of 18.1(8) GPa, being as soft as a rare gas, molecular solids, or organometallic compounds. Moreover, its response to pressure is anis…

Diffractionchemistry.chemical_classification010405 organic chemistryIodidemacromolecular substancesCrystal structure010402 general chemistry01 natural sciences0104 chemical sciencesCharacterization (materials science)Inorganic ChemistryCrystallographyTetragonal crystal systemstomatognathic systemchemistryHigh pressureFISICA APLICADAPhysical and Theoretical Chemistry
researchProduct