Search results for "Sage"

Modélisation opérationnelle du paysage. Chapitre 5

2008

Caractérisation du paysage dans les approches écologiques

2008

Le marché immobilier, révélateur du prix du paysage

2008

Collection : Information Géographique et Aménagement du Territoire - Traité IGAT; National audience

Le choix de descripteurs paysagers en tant qu'indicateurs d'un risque épidémiologique

2005

National audience; Echinococcus multilocularis (Em) est un parasite responsable chez l'homme d'une maladie grave : l'échinococcose alvéolaire. La contamination humaine peut se produire par ingestion accidentelle d'œufs du parasite. Un programme européen d'épidémiosurveillance, EchinoRisk, est actuellement en cours. En France, ce programme, mené conjointement par l'ERZ (Entente interdépartementale de lutte contre la rage et autres zoonoses) et l'AFSSA (Agence française de sécurité sanitaire des aliments), a permis jusqu'à présent de collecter 5 820 échantillons localisés de fèces de renards. À ce jour, 2 305 échantillons ont été analysés parmi lesquels 62 ont révélé la présence du parasite. …

Communication visuelle autour du Camp du Château à Salins-les-Bains (Jura, France) : mise en évidence d’un réseau de relations visuelles à l’âge du B…

2018

Des campagnes de prospections systématiques menées depuis plusieurs années dans le secteur du Camp du Château à Salins-les-Bains ont permis la mise au jour de 40 dépôts de l’âge du Bronze dans des contextes topographiques particuliers. La bonne précision de leur localisation permet de mesurer les liens de perceptibilité entre les lieux de dépôt et des points marquants du paysage naturel et social de l’âge du Bronze, en particulier des sites de hauteur. La topographie de la région a en effet favorisé la constitution d’une véritable toile de relations visuelles tout autour du Camp du Château. Les dépôts semblent marquer les frontières de l’espace visible depuis celui-ci. La mise en place d’un…

Le paysage, de l'information à l'élaboration d'une culture paysagère : vers des médiations paysagères au service des acteurs de l'aménagement du terr…

2005

Landscape is shaped by a community of people who do not necessarily share the same intentions and/or expectations towards landscape. Thus, the representations of the people involved (planners, decisions makers, users) influence the way landscape is being taken into consideration in the field of town-and-country-planning. The multiple representations hinder communication while projects are being discussed, yet the interlocutors are bound to come to a general agreement to guarantee an negociated-and-shared achievement. On the other hand, the minimal education about landscape is necessary to apprehend the landscaped problematics of the concerned areas; nevertheless, people usually miss the poi…

Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families.

2001

Dosage compensation in Drosophila is mediated by a complex of proteins and RNAs called the "compensasome." Two of the genes that encode proteins of the complex, maleless (mle) and males-absent-on-the-first (mof), respectively, belong to the DEAH helicase and MYST acetyltransferase gene families. We performed comprehensive phylogenetic and structural analyses to determine the evolutionary histories of these two gene families and thus to better understand the origin of the compensasome. All of the members of the DEAH and MYST families of the completely sequenced Saccharomyces cerevisiae and Caenorhabditis elegans genomes, as well as those so far (June 2000) found in Drosophila melanogaster (f…

Extremely low frequency electromagnetic fields (ELF-EMFs) induce in vitro angiogenesis process in human endothelial cells.

2008

Effects of extremely low frequency (ELF) electromagnetic fields (EMFs) on activation of angiogenesis were analysed using cultured umbilical human vein endothelial cells (HUVECs). The cultures were exposed to a sinusoidal EMF to intensity of 1 mT, 50 Hz for up to 12 h. EMFs increased the degree of endothelial cell proliferation and tubule formation, coupled by an acceleration in the process of wound healing. Since this process is physiologically accompanied by a large modification in the structural organization of actin and focal adhesions, we analyzed the rearrangement of some cytoskeleton elements demonstrating a major reorganization of the fibres and of the focal adhesion complexes after …

Spatially restricted expression of PlOtp, a Paracentrotus lividus Orthopedia-related homeobox gene, is correlated with oral ectodermal patterning and…

1999

ABSTRACT Several homeobox genes are expressed in the sea urchin embryo but their roles in development have yet to be elucidated. Of particular interest are homologues of homeobox genes that in mouse and Drosophila are involved in patterning the developing central nervous system (CNS). Here, we report the cloning of an orthopedia (Otp)-related gene from Paracentrotus lividus, PlOtp. Otp is a single copy zygotic gene that presents a unique and highly restricted expression pattern. Transcripts were first detected at the mid-gastrula stage in two pairs of oral ectoderm cells located in a ventrolateral position, overlying primary mesenchyme cell (PMC) clusters. Increases in both transcript abund…

Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis

2015

Genomic imprinting is implicated in the control of gene dosage in neurogenic niches. Here we address the importance of Igf2 imprinting for murine adult neurogenesis in the subventricular zone (SVZ) and in the subgranular zone (SGZ) of the hippocampus in vivo. In the SVZ, paracrine IGF2 is a cerebrospinal fluid and endothelial-derived neurogenic factor requiring biallelic expression, with mutants having reduced activation of the stem cell pool and impaired olfactory bulb neurogenesis. In contrast, Igf2 is imprinted in the hippocampus acting as an autocrine factor expressed in neural stem cells (NSCs) solely from the paternal allele. Conditional mutagenesis of Igf2 in blood vessels confirms t…