Search results for "Saponines"

showing 3 items of 3 documents

Chemical and biological study of saponins isolated from three malagasy species belonging to Caryophyllaceae, Pittosporaceae and Solanaceae families

2013

This thesis was carried out in the Laboratory of Pharmacognosy, in the Pharmacy section of the University of Burgundy. The principal theme of this laboratory is the research of natural compounds from tropical biodiversity, mainly saponins. In this context, the study of Malagasy plants, Polycarpaea corymbosa Lamk. (CARYOPHYLLACEAE), Pittosporum verticillatum Bojer subsp. verticillatum (PITTOSPORACEAE), Solanum incanum L. and S. heteracanthum Dunal. (SOLANACEAE) led to the isolation of fifteen natural glycosides by column chromatography, medium pressure liquid chromatography, flash chromatography, and vacuum liquid chromatography. The structures were elucidated mainly by the use of spectrosco…

[ SDV.BV ] Life Sciences [q-bio]/Vegetal Biology[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyFlore MalgacheCytotoxicityTriterpènesSaponinsTriterpenesNMRRMNMalagasy floraSaponines[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyCytotoxicitéStéroïdesSteroides[SDV.BV] Life Sciences [q-bio]/Vegetal Biology
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Isolation and caracterisation of saponins from three plants of Araliaceae and Dracaenaceae families and evaluation of their cytotoxic activities on t…

2010

The interest of the substances from natural origin, potentially antitumor led us to interest in triterpenoid and steroidal saponins of plants from the African biodiversity belonging to the Araliaceae and Dracaenaceae families of plants. Indeed, of the former studies undertaken on some plants of these two families led to obtaining complex and original molecules having excellent cytotoxic, immuno-modulating, anti-inflammatory properties. Within sight of these results we undertook pharmaco-chemical investigations on Cussonia arborea (Araliaceae), Dracaena deisteliana, and Dracaena arborea (Dracaenaceae), medicinal plants usually used in african traditional pharmacopeia to treat various disease…

[SDV.SA] Life Sciences [q-bio]/Agricultural sciences[ SDV.BV ] Life Sciences [q-bio]/Vegetal Biology[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyCytotoxicityCussonia arboreaDracaena arboreaDracaena deistelianaTriterpenoid saponinsDracaenaceaeSaponines triterpéniquesSaponines stéroïdiquesCytotoxicité[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyAraliaceae[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciencesSteroidal saponins
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Isolement et caractérisation de saponosides extraits de deux plantes médicinales : Cyclamen africanum, Zygophyllum cornutum et évalution de leur acti…

2014

The appearance of several diseases, such as cancer, diabetes, high blood pressure and spread of infections mutagenic virus type can be linked to the quality and lifestyle that we lead today. Indeed, several studies on the factors triggering these so-called "morbid" long-or short-term illnesses are related to stress and quality of food consumed, whether of plant and animal origin. These diseases are becoming a common occurrence, they affect different races and all classes of society. According ethnobotanical research, naturally occurring substances, allowed civilizations to survive deadly diseases. For example, we thus find references to periods of malarial fever in China and one of the symp…

protéines réponse inflammatoire (PRI)[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyMass spectrometry1D and 2D NMRZygophyllum cornutumMédiateurs pro-inflammatoire (COX-2)Anti-inflammatoires (AINS)INOSPro-inflammatory mediatorsProtein inflammatory response (PRI)Activité anti inflammatoireAnti inflammatory activitySaponins triterpeneCyclamen africanumCOX-2Spectrométrie de masseRMN 1DRMN 2DSaponines triterpéniques[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyAnti-inflammatory drugs (NSAIDs)TNF -αPGE2[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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