Search results for "Satu"
showing 10 items of 1367 documents
Characterization of inductors in partial saturation for SMPS applications
2017
The exploitation of partially saturated inductors in Switching Mode Power Supply (SMPS) is a key strategy for reducing the size of SMPS and increasing their power density [1]. However an accurate characterization and modellization of each inductor is needed for a correct design and control of the SMPS [2]. Most of inductors' datasheets only indicate the nominal inductance at low current. Anyway, when the inductor is subjected to a higher current, the value of the inductance is lessened. Moreover, inductance meters often actuate their measurements at no or moderate DC bias. In this work we describe the realization of an automated test bench (Fig. 1) for characterizing an inductor under varia…
Involvement of Microglia in Neurodegenerative Diseases: Beneficial Effects of Docosahexahenoic Acid (DHA) Supplied by Food or Combined with Nanoparti…
2021
Neurodegenerative diseases represent a major public health issue and require better therapeutic management. The treatments developed mainly target neuronal activity. However, an inflammatory component must be considered, and microglia may constitute an important therapeutic target. Given the difficulty in developing molecules that can cross the blood–brain barrier, the use of food-derived molecules may be an interesting therapeutic avenue. Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid (22:6 omega-3), has an inhibitory action on cell death and oxidative stress induced in the microglia. It also acts on the inflammatory activity of microglia. These data obtained in vitro or…
Apsūdzība un tās saturs kriminālprocesā
2021
Apsūdzības satura problemātika aptver dažādus kriminālprocesa aspektus gan materiālajās, gan procesuālajās tiesībās. Maģistra darba mērķis ir pētīt un analizēt praksē pastāvošās problēmas saistībā ar apsūdzību, tās saturu, standartu un apsūdzības grozīšanu, kā arī izteikt viedokli un piedāvāt iespējamos risinājumus, piemēram, par to, kā acīmredzami apsūdzības trūkumi novēršami pirms iztiesāšanas uzsākšanas, un cik plašas tiesības ir tiesai konstatēt no apsūdzības atšķirīgus faktiskos apstākļus. Maģistra darbā pētītas apsūdzības funkcijas, saturs un standarts, analizēti jautājumi par apsūdzības grozīšanu un apsūdzībā pieļautu kļūdu labošanu, noskaidrotas nekvalitatīvas apsūdzības sekas un ap…
Nocturnal intermittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database cohort study.
2014
Systemic hypertension is associated with obstructive sleep apnoea syndrome (OSAS) but the pathophysiological mechanisms are incompletely understood. A collaborative European network of 24 sleep centres established a European Sleep Apnoea Database to evaluate cardiovascular morbidity associated with OSAS.11 911 adults referred with suspected OSAS between March 2007 and September 2013 underwent overnight sleep studies, either cardiorespiratory polygraphy or polysomnography. We compared the predictive value of the apnoea–hypopnoea index (AHI) and 4% oxygen desaturation index (ODI) for prevalent hypertension, adjusting for relevant covariates including age, smoking, obesity, dyslipidaemia and d…
Reticulocytes in untreated obstructive sleep apnoea.
2008
Background and Aim. The short, repetitive hypoxaemic episodes observed in obstructive sleep apnoea (OSA) may determine small augmentations in mature red blood cells. It is unknown whether they affect reticulocyte release. This study explored whether the number and degree of maturation of circulating reticulocytes may be altered in OSA, possibly through the effect of erythropoietin. Methods. Fifty male adult patients with suspected OSA, normoxic during wakefulness, were studied. After nocturnal polysomnography, a blood sample was withdrawn for blood cells count, erythropoietin, iron and transferrin determination. Reticulocyte concentration and degree of immaturity [high (H), medium (M), or l…
Observation of ventilation-induced Spo(2) oscillations in pigs: first step to noninvasive detection of cyclic recruitment of atelectasis?
2010
High arterial partial oxygen pressure (Pao(2)) oscillations within the respiratory cycle were described recently in experimental acute lung injury. This phenomenon has been related to cyclic recruitment of atelectasis and varying pulmonary shunt fractions. Noninvasive detection of Spo(2) (oxygen saturation measured by pulse oximetry) as an indicator of cyclic collapse of atelectasis, instead of recording Pao(2) oscillations, could be of clinical interest in critical care. Spo(2) oscillations were recorded continuously in three different cases of lung damage to demonstrate the technical feasibility of this approach. To deduce Pao(2) from Spo(2), a mathematical model of the hemoglobin dissoci…
Target oxygen levels in preterm neonates
2013
To achieve postnatal adaptation newly born infant need to aerate the lungs, reduce pulmonary vascular resistance, and initiate oxygen and carbon dioxide exchange. The cornerstone of newborn resuscitation resides therefore in the establishment of a functional residual capacity and an adequate oxygenation. Recent guidelines have established guidelines concerning oxygen supplementation in preterm infants in the delivery room (DR); however, they are vague and unspecific. Herewith, we will address available information regarding the use of oxygen supplementation in the DR in preterm infants to satisfactorily overcome postnatal adaptation. Introduction: Resuscitation of the newborn is considered …
Comment to the Editorial by KS Park and EW Kang “Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstruct…
2019
We thank doctors Park and Kang for their editorial that well summarized our article. Our common belief is that one of the possible consequences of untreated obstructive sleep apnea (OSA) is an accelerated deterioration of kidney function, and that more knowledge would be necessary on the possible protective effects of OSA treatments. To our knowledge, so far the only OSA therapy whose effects on renal function have been tested is continuous positive airway pressure (CPAP), and most , although not all studies, have demonstrated its benefits. Our own study, while confirming benefits of fixed CPAP, has demonstrated little effect of auto-adjusting CPAP (APAP). This finding may be of relevance a…
Dynamic determination of oxygenation and lung compliance in murine pneumonectomy.
2011
Thoracic surgical procedures in mice have been applied to a wide range of investigations, but little is known about the murine physiologic response to pulmonary surgery. Using continuous arterial oximetry monitoring and the FlexiVent murine ventilator, the authors investigated the effect of anesthesia and pneumonectomy on mouse oxygen saturation and lung mechanics. Sedation resulted in a dose-dependent decline of oxygen saturation that ranged from 55% to 82%. Oxygen saturation was restored by mechanical ventilation with increased rate and tidal volumes. In the mouse strain studied, optimal ventilatory rates were a rate of 200/minute and a tidal volume of 10 mL/kg. Sustained inflation pressu…
On partially saturated formations of finite groups
2007
Various types of partially saturated formations and connections between them are considered. It is shown that partially saturated formations can be characterized as classes of finite groups with generalized central series. A theorem on the decomposition of an FG-module into a sum of two submodules with special properties is proved.Bibliography: 26 titles.