Search results for "ScIM"
showing 10 items of 263 documents
gamma-Aminobutyric acid and cholinergic transmission in the guinea-pig ileum.
1983
1. The effects of GABA on release of acetylcholine and on contractility of the smooth muscle were studied in the myenteric plexus-longitudinal muscle preparation of the guinea pig. Acetylcholine was determined as radiolabelled transmitter from strips preloaded with 3H-choline. 2. GABA (1–300 μM) caused an increase in resting tension of smooth muscle as well as an increase in release of acetylcholine that was considerably reduced by tetrodotoxin. The facilitation by GABA of acetylcholine release exhibited a marked tachyphylaxis. The increase in muscle tension was clearly related to the increase in acetylcholine release. Muscimol (0.1–10 μM) also enhanced the release of acetylcholine. The eff…
Induction of neurosteroid synthesis by NMDA receptors in isolated rat retina: a potential early event in excitotoxicity
1998
Here we investigated the possible regulation of neurosteroidogenesis by N-methyl-D-aspartic acid (NMDA) receptor activation and addressed the hypothesis that neurosteroid synthesis may be involved in acute excitotoxicity. In the isolated retina, exposure to NMDA modified pregnenolone and pregnenolone sulphate formation. This effect was dose and time dependent, the synthesis being increased by relatively moderate NMDA doses (1-100 microM) within 30 min exposure and reduced to its control value by 60 min or by raising drug concentrations. NMDA-stimulated neurosteroid synthesis was blocked by (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine hydrogen maleate (MK-801) and 3(2-ca…
Morphologische und funktionelle Evaluation pulmonaler Gefäßanomalien mittels schneller MR-Techniken
2002
Purpose: To evaluate breath-hold MR techniques for morphologic and functional assessment of vascular abnormalities of the pulmonary vasculature. Patients and Methods: 13 patients aged 11 to 60 years with different vascular abnormalities of the pulmonary vasculature (5 patients with 16 arteriovenous malformations, 8 patients with partial anomalous pulmonary venous return) underwent MR imaging at 1.5 T. For morphological assessment, a contrast-enhanced 3D MR angiography (ce-MRA) was performed after a timing run. Segmented cine- and velocity-encoded GRE sequences were used for delineation of associated cardiac septal defects and for determination of systemic left-to-right or intrapulmonary shu…
Una nuova batteria di test di memoria di riconoscimento verbale e non verbale: uno studio preliminare.
2010
L’esperienza della tutorialità nei contesti educativi con adolescenti migranti soli.
2020
L’esperienza della tutorialità, nei processi educativi e formativi di presa in carico dei minori migranti soli o non accompagnati, si presenta come un terreno fertile e, per certi aspetti, nuovo da esplorare. Su questo terreno si trovano a confrontarsi gli educatori e le educatrici che operano nella vasta rete di accoglienza e protezione dei migranti. La recente attenzione verso figure come il tutor/case manager, l’educatore di riferimento o il tutore legale volontario, costituisce un oggetto di indagine privilegiato in cui convergono diversi ambiti del sapere: dalla pedagogia alle scienze dell’educazione, dalla psicologia alle scienze dell’organizzazione. Nella pratica educativa, la tutori…
MARKET, BUSINESS MANAGEMENT NEEDS & DISCRIMINATION
2017
La secessione nel diritto internazionale
2001
Secessione e diritto internazionale: un'analisi del dibattito
2015
It is traditionally maintained that international law neither prohibits nor authorizes secession. This affirmation still maintains much of its validity despite recent attempts to demonstrate the emergence of a prohibition to secede hinged on the respect due to peremptory norms of international law or on the extension of the subjective scope of the principle of territorial integrity towards secessionist groups. On the other hand, the idea of the existence of a right to remedial secession does not yet correspond to positive international law. However, the fact that international law neither prohibits nor authorizes separation does not imply that secession is totally unregulated. Firstly, inte…