Search results for "Sclerosis"

The Mini Mental State Examination (MMSE) for Cognitive Impairment in multiple sclerosis (ms): a two years Longitudinal study in 300 patients.

2008

THORACIC SYRINGOMYELIA IN A PATIENT WITH AMYOTROPHIC LATERAL SCLEROSIS

2015

We report a patient with bulba r - onset, clinically defined, sporadic amyotrophic lateral sclerosis bearing an isolated syringomyelia of the lower thoracic portion of the spinal cord. This is a very unusual association between two rare and progressive disorders, both affecting the spinal motoneurons. Syringomyelia might have acted as a phenotypic modifier in this ALS patient.

Assessment of volume and density of epicardial fat: comparison between CT calcium score and CT coronary angiography scans.

2015

Aims and objectives Methods and materials Results Conclusion Personal information References

Augmentative Alternative Communication using Eyelid Movement Remote Detection by Speckle Patterns Tracking System for Amyotrophic Lateral Sclerosis D…

2017

The implementation of augmentative alternative communication optical device for ALS speech problem is presented. The sensor is based on temporal tracking of back-reflected secondary speckle patterns generated when illuminating an eyelid with a laser.

Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages : relevance in the context of atherosclerosis

2015

Objective— Liver X receptors (LXRs) modulate cholesterol and fatty acid homeostasis as well as inflammation. This study aims to decipher the role of LXRs in the regulation of polyunsaturated fatty acid (PUFA) synthesis in macrophages in the context of atherosclerosis. Approach and Results— Transcriptomic analysis in human monocytes and macrophages was used to identify putative LXR target genes among enzymes involved in PUFA biosynthesis. In parallel, the consequences of LXR activation or LXR invalidation on PUFA synthesis and distribution were determined. Finally, we investigated the impact of LXR activation on PUFA metabolism in vivo in apolipoprotein E–deficient mice. mRNA levels of acyl…

Persistent Tonic Facial Contraction: A Local Brain-Stem Sign

1993

Impairment of facial motility associated with contralateral hemiparesis is characteristic of pontine lesions. In the Millard-Gubler and Foville syndromes, involvement of the facial nerve is nuclear or infranuclear, resulting in a peripheral-type palsy. Conditions of pontine origin showing hyperactivity of facial muscles are facial myokymia and Brissaud’s syndrome. Brissaud and Sicard [4] reported low-frequency phasic cramplike facial contractions and contralateral hemiparesis in inflammatory brain-stem processes.

Behavior of patients at high risk of developing contrast induced nephropathy after coronary procedures

2012

SYNTAX score is associated with in-hospital mortality as assessed by GRACE risk score in patients with acute myocardial infarction

2013

Longitudinal quantitative MRI assessment of cortical damage in multiple sclerosis: A pilot study

2017

PURPOSE Quantitative MRI (qMRI) allows assessing cortical pathology in multiple sclerosis (MS) on a microstructural level, where cortical damage has been shown to prolong T1 -relaxation time and increase proton density (PD) compared to controls. However, the evolution of these changes in MS over time has not been investigated so far. In this pilot study we used an advanced method for the longitudinal assessment of cortical tissue change in MS patients with qMRI in comparison to cortical atrophy, as derived from conventional MRI. MATERIALS AND METHODS Twelve patients with relapsing-remitting MS underwent 3T T1 /PD-mapping at two timepoints with a mean interval of 12 months. The respective co…

Familial hypercholesterolæmia in children and adolescents: Gaining decades of life by optimizing detection and treatment

2015

Contains fulltext : 155263.pdf (Publisher’s version ) (Open Access) Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated early in childhood, individuals with FH can have normal life expectancy. This consensus paper aims to improve awareness of the need for early detection and management of FH children. Familial hypercholesterolaemia is diagnosed either on phenotypic criteria, i.e. an elevated low-density lipoprotein cholesterol (LDL-C) level plus a family history of elevated LDL-C, premature coronary artery disease and/or genetic diagnosis, or positive genetic testin…