Search results for "Scoparia"

showing 4 items of 4 documents

Inhibition of Trypanosoma cruzi by plant extracts used in Chinese medicine.

2004

In this work, we assessed the effect of extracts obtained from 17 plants used in traditional Chinese medicine. These extracts were tested in vitro with the epimastigote form of Trypanosoma cruzi, clone Bra C(15) C(2), at 27 degrees C in F-29 medium at a concentration of 100 microg/ml in axenic cultures. Allopurinol was used as reference drug. Seven plant extracts showed inhibitory activities lower than 25%. Pueraria lobata, Mahonia beaei, Dictamus dasycarpus, Kochia scoparia, Sophora flavescens and Ligustrum lucidum showed effects with inhibition values between 25% and 60%, whereas Lithospermum erythrorhizon, Saussurea lappa, Melia toosendan and Cinnamomum cassia showed the greatest inhibit…

MalePuerariaTrypanosoma cruziMahoniaPharmacognosyPlant RootsInhibitory Concentration 50Parasitic Sensitivity TestsCassiaDrug DiscoveryAnimalsMedicine Chinese TraditionalRats WistarPharmacologySophora flavescensPlants MedicinalbiologyTraditional medicinePlant StemsPlant ExtractsGeneral Medicinebiology.organism_classificationLithospermum erythrorhizonTrypanocidal AgentsRatsFruitSeedsPlant BarkScopariaRhizomeCinnamomumPhytotherapyFitoterapia
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2021

The genus Centaurea is recognized in folk medicine for anti-inflammatory, anti-itch, antitussive, purgative, astringent, and tonic activities. To study the chemical determinant for antimicrobial activity essential oils (EOs), five Centaurea species were analyzed including: C. scoparia, C. calcitrapa, C. glomerata, C. lipii and C. alexandrina. Conventional hydro-distillation (HD) and microwave-assisted extraction (MAE), as new green technologies, were compared for the extraction of essential oils. GC/MS analysis identified 120 EOs including mostly terpenoid except from C. lipii and C. alexandrina in which nonterpenoids were the major constituents. Major terpenoids included spathulenol, caryo…

Microbiology (medical)biologyTraditional medicine010405 organic chemistryChemistryAspergillus nigerAsteraceaebiology.organism_classificationAntimicrobial01 natural sciencesBiochemistryMicrobiologyDNA gyraseTerpenoid0104 chemical sciences010404 medicinal & biomolecular chemistryInfectious DiseasesCentaureaPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsScopariaAntibacterial activityAntibiotics
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Seawater carbonate chemistry and percentage cover of macroalgal species at three locations at Vulcano, Italy

2017

Beneficial effects of CO2 on photosynthetic organisms will be a key driver of ecosystem change under ocean acidification. Predicting the responses of macroalgal species to ocean acidification is complex, but we demonstrate that the response of assemblages to elevated CO2 are correlated with inorganic carbon physiology. We assessed abundance patterns and a proxy for CO2:HCO3- use (delta 13C values) of macroalgae along a gradient of CO2 at a volcanic seep, and examined how shifts in species abundance at other Mediterranean seeps are related to macroalgal inorganic carbon physiology. Five macroalgal species capable of using both HCO3- and CO2 had greater CO2 use as concentrations increased. Th…

Ocean Acidification International Coordination Centre (OA-ICC)TemperateRegistration number of speciesSalinityCaulerpa proliferaCommunity composition and diversityBicarbonate ion standard deviationUdotea petiolatainorganicAlkalinity total standard deviationAlkalinitySargassum muticumDictyota dichotomaHalopteris scopariaYearsCystoseira brachycarpaExperimentTemperature waterCarbon inorganic dissolvedCystoseira foeniculaceaCaulerpa racemosaCalculated using seacarb after Nisumaa et al 2010Cystoseira foeniculataAragonite saturation stateAlkalinity totaltotalCO2 ventpHTemperaturedissolvedCarbonate ionPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)Acetabularia acetabulumJania rubensCarbon dioxide standard deviationEarth System Researchδ13CLipid contentstandard deviationField observationUniform resource locator link to referenceCystoseira crinitaCoverageCalcite saturation stateLocationwaterSiteRocky-shore communityFigureBenthosUniform resource locator/link to referenceOcean Acidification International Coordination Centre OA ICCMediterranean SeaCarbon inorganic dissolved standard deviationTypeBicarbonate ionDictyopteris polypodioidesDilophus fasciolaCalculated using seacarb after Nisumaa et al. (2010)SpeciesCystoseira compressaEvent labelCarbonate system computation flagpH standard deviationCarbonate ion standard deviationMassFugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonOxygenPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideRocky shore communityEntire communityFugacity of carbon dioxide water at sea surface temperature wet airPadina pavonicaSeasonδ13C standard deviationCoast and continental shelfCodium bursaTableCystoseira barbarta
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Synthesis of C3/C1-Substituted Tetrahydroisoquinolines

2015

A broad biological screening of the natural alkaloid N-methylisosalsoline (2) extracted from Hammada scoparia leaves against a panel of human and parasitic proteases revealed an interesting activity profile of 2 towards human 20S proteasome. This outcome suggests that the 1,2,3,4-tetrahydroisoquinoline skeleton may be exploited as a template for the development of novel anticancer agents. In this article, we report the synthesis and chemical characterization of a new series of isosalsoline-type alkaloids (10-11) with variations at N2 and C3 positions with respect to the natural Compound 2, obtained by a synthetic strategy that involves the Bischler-Napieralski cyclization. The substrate for…

Proteases<i>N</i>-methylisosalsolineStereochemistryPharmaceutical SciencenitroalkeneNitroalkene20s proteasomeArticleAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryTetrahydroisoquinolinesN-methylisosalsolineDrug DiscoveryAnimalsHumansParasitesPhysical and Theoretical ChemistryBischler-Napieralski condensationCell ProliferationBischler-Napieralski condensation; N-methylisosalsoline; nitroalkene; proteasome; tetrahydroisoquinolineChemistryTetrahydroisoquinolineAlkaloidOrganic ChemistrySubstrate (chemistry)Hammada scopariaproteasomeChemistry (miscellaneous)Molecular MedicineCattleAmine gas treatingtetrahydroisoquinolinePeptide Hydrolases
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