Search results for "Secondary"

showing 10 items of 1765 documents

Calcium-dependent conformational changes of membrane-bound Ebola fusion peptide drive vesicle fusion

2003

AbstractThe fusogenic subdomain of the Ebola virus envelope glycoprotein is an internal sequence located ca. 20 residues downstream the N-terminus of the glycoprotein transmembrane subunit. Partitioning of the Ebola fusion peptide into membranes containing phosphatidylinositol in the absence of Ca2+ stabilizes an α-helical conformation, and gives rise to vesicle efflux but not vesicle fusion. In the presence of millimolar Ca2+ the membrane-bound peptide adopts an extended β-structure, and induces inter-vesicle mixing of lipids. The peptide conformational polymorphism may be related to the flexibility of the virus–cell intermembrane fusogenic complex.

Vesicle fusionEbola glycoproteinSpectrophotometry InfraredProtein ConformationvirusesBiophysicsPeptideBiologymedicine.disease_causePhosphatidylinositolsBiochemistryMembrane FusionProtein Structure Secondarychemistry.chemical_compoundProtein structureFusion peptideMembranes (Biologia)Structural BiologyGeneticsmedicinePhosphatidylinositolMolecular Biologychemistry.chemical_classificationEbola virusVesicleCircular DichroismLipid bilayer fusionViral fusionWaterMembranes ArtificialCell BiologyEbolavirusLipidsTransmembrane proteinPeptide FragmentsBiochemistrychemistryLiposomesBiophysicsCalciumPèptidsPeptide–lipid interactionViral Fusion Proteins
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A suggested role for secondary flow in the stimulation of the cochlear hair cell

1985

The mammalian Corti organ and the reptilian basilar papilla are structures with a curved surface, which vibrate in a fluid medium. This paper is concerned with the role played by the geometric shape of these organs in cochlear hydrodynamics. In association with vibrating structures such as these organs, it can be expected that a stationary current will be initiated due to a nonlinear phenomenon in the boundary layer known as secondary flow. This phenomenon may explain the source of the mechanical nonlinearity in the cochlea.

Vestibular systemPhysicsCommunicationGeneral Computer ScienceSense organbusiness.industryStimulationGeometric shapeSecondary flowmedicine.anatomical_structureotorhinolaryngologic diseasesmedicineBiophysicsInner earsense organsCurrent (fluid)businessCochleaBiotechnologyBiological Cybernetics
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Approach to mathematics in textbooks at tertiary level – exploring authors’ views about their texts

2012

The aim of this article is to present and discuss some results from an inquiry into mathematics textbooks authors’ visions about their texts and approaches they choose when new concepts are introduced. Authors’ responses are discussed in relation to results about students’ difficulties with approaching calculus reported by previous research. A questionnaire has been designed and sent to seven authors of the most used calculus textbooks in Norway and four authors have responded. The responses show that the authors mainly view teaching in terms of transmission so they focus mainly on getting the mathematical content correct and ‘clear’. The dominant view is that the textbook is intended to he…

VisionMathematics (miscellaneous)Relation (database)Postsecondary educationApplied MathematicsComputingMilieux_COMPUTERSANDEDUCATIONMathematical contentMathematics educationTertiary levelMathematics instructionEducationMathematicsFocus (linguistics)International Journal of Mathematical Education in Science and Technology
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Case report: Bilateral femoral fracture in a young fertile age woman

2009

Vitamin D deficit secondary hyperparathyroidism myopathy hip fractures
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Wage penalties for post-secondary education interruption in France

2017

International audience; In France, more and more young people are interrupting their post-secondary education (Mora, 2014) even if re-entering higher education implies all kinds of costs. Yet, little attention has been given so far to the eect of temporary dropout on future wages but it has been studied in other countries. We have attempted to measure the net effect of schooling discontinuities on young wages on the basis of a study of a sample of youth who left post-secondary education in 1998 and returned a few years later. Firstly, from an OLS regression, temporary interruption seems to have a positive effect on wages. However, people who interrupted temporary their education could have …

Wage penaltyinterruption[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Educationpost-secondary education[ SHS.EDU ] Humanities and Social Sciences/EducationFrance
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A posteriori error estimates for Webster's equation in wave propagation

2015

We consider a generalised Webster’s equation for describing wave propagation in curved tubular structures such as variable diameter acoustic wave guides. Webster’s equation in generalised form has been rigorously derived in a previous article starting from the wave equation, and it approximates cross-sectional averages of the propagating wave. Here, the approximation error is estimated by an a posteriori technique. peerReviewed

Wave propagationWave propagationApplied MathematicsMathematical analysista111Tubular domainDynamical Systems (math.DS)Acoustic waveWave equationPrimary 37L05. Secondary 35L05 35L20 47N70 93C20A posteriori error analysisMathematics - Analysis of PDEsApproximation errorFOS: MathematicsCalculusA priori and a posterioriWebster's modelMathematics - Dynamical SystemsAnalysisAnalysis of PDEs (math.AP)MathematicsVariable (mathematics)
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Booster vaccination after neonatal priming with acellular pertussis vaccine.

2010

After a birth dose of acellular pertussis (aP) and diphtheria (DT)aP-hepatitis B virus (HBV)-inactivated polio vaccine (IPV)/ Haemophilus influenza type b (Hib) at 2, 4, and 6 months, a booster dose of DTaP-HBV-IPV/Hib at 12 to 23 months induced strong anti-pertussis booster responses. Thus, neonatal aP priming did not lead to immune tolerance to pertussis antigens. However, it elicited bystander interference on HBV, Hib, and diphtheria responses.

Whooping CoughFilamentous haemagglutinin adhesinImmunization SecondaryBooster dosemedicine.disease_causecomplex mixturesVirusPolio vaccineVaccines AcellularmedicineHumansWhooping coughHepatitis B virusPertussis VaccineDose-Response Relationship Drugbusiness.industryDiphtheriaVaccinationInfant Newbornvirus diseasesInfantmedicine.diseasePrognosisVirologyVaccinationPediatrics Perinatology and Child HealthImmunologybusinessFollow-Up StudiesThe Journal of pediatrics
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Effects of postharvest partial dehydration and prolonged treatments with ethylene on transcript profiling in skins of wine grape berries.

2010

For certain food products, postharvest controlled stresses or treatments with specific elicitors are applied to induce desired physical/chemical changes and/or to positively affect phytochemical content. This is the case of wine grapes where both strategies, singularly applied or coupled, can be used to modulate berry composition and, as a consequence, affect wine quality traits. Since the knowledge of the effects of these postharvest treatments on berry metabolism and the regulation of gene expression is very limited, a large-scale transcriptome analysis has been carried out, using an oligo-based microarray (14,562 probes) on skins of wine grape (Vitis vinifera L.) berries subjected to deh…

Winefungifood and beveragesBerryHorticultureBiologymedicine.diseaseWine grapeTranscriptomeHorticulturegene expression genomics microarray polyphenols secondary metabolism transcriptome Vitis viniferaPhytochemicalPolyphenolSettore AGR/07 - Genetica AgrariamedicinePostharvestDehydrationNon disponibili
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PARTNERSHIP BETWEEN TEACHER AND SECONDARY SCHOOL STUDENT THROUGH LEARNING MATHEMATICS

2016

This article examines secondary school student and teachers cooperation through learning mathematics. The aim of the study is to find out whether the teacher and student cooperation is a partnership. The partnership is viewed as a cooperation where involved work toward mutual goals. Secondary school student - teacher partnership is possible if the teacher trusts students and together with them chooses the learning objectives, the teaching aids and methods of learning. Students take responsibility for their choices and they are motivated to accomplish them if there is possibility to make a choice. The article deals with teachers' views on teaching and students' opinions about what helps and …

Work (electrical)General partnershipTeaching methodPolitical sciencePedagogyMathematics educationComputingMilieux_COMPUTERSANDEDUCATIONlearning mathematics; partnership; secondary school students; teachersMathematicsSOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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Dip Phenomenon in High-Curved Turbulent Flows and Application of Entropy Theory

2018

The estimation of velocity profile in turbulent open channels is a difficult task due to the significant effects of the secondary flow. The present paper investigates the mechanism of the velocity-dip phenomenon, whereby the location of the maximum velocity appears to be below the free surface. Previous studies conducted in straight channels relate the mechanism of the velocity-dip phenomenon to secondary flow induced by anisotropy of turbulence. This work focuses on high-curved channels where the secondary motion, which is also induced by the channel’s curvature, evolves along the bend. The width-to-depth ratio, B/h, is one of the most important parameters that are affecting the secondary …

Work (thermodynamics)lcsh:Hydraulic engineeringAspect ratioriver0208 environmental biotechnologyGeography Planning and Development02 engineering and technologyAquatic ScienceCurvatureBiochemistrySettore ICAR/01 - Idraulicalcsh:Water supply for domestic and industrial purposeslcsh:TC1-978AnisotropyWater Science and TechnologyPhysicslcsh:TD201-500Turbulenceturbulencesecondary motionMechanicspredictionrivers; meanders; turbulence; secondary motion; predictionSecondary flowrivers020801 environmental engineeringFlow velocityFree surfacemeandersmeanderWater; Volume 10; Issue 3; Pages: 306
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