Search results for "Secondary"
showing 10 items of 1765 documents
(DIS)Assembly and Structural Stability of mtHsp60 and its Precursor NaÏve Form
2015
Heat shock protein 60kDa is a molecular chaperone (GroEL human homolog) that assists protein folding in mitochondria (mtHsp60). It is synthesized in the cell cytoplasm as a higher molecular weight precursor form (p-mtHsp60) containing a N-terminal targeting sequence, that is cleaved after import into the mitochondrial matrix [1, 2].It has been established, and demonstrated by various techniques, Hsp60 can accumulate in the cytosol, in various pathological conditions (i.e., cancer and chronic inflammatory diseases). The cytosolical Hsp60 accumulation mechanism may occur with or without mitochondrial release concomitantly, so that in the cytosol the two types of 60 kDa chaperonin proteins, (m…
Entrepreneurship Training and Self-Employment among University Graduates
2012
In economies characterized by low labor demand and high rates of youth unemployment, entrepreneurship training has the potential to enable youth to gain skills and create their own jobs. This paper presents experimental evidence on a new entrepreneurship track that provides business training and personalized coaching to university students in Tunisia. Undergraduates in the final year of licence appliquee were given the opportunity to graduate with a business plan instead of following the standard curriculum. This paper relies on randomized assignment of the entrepreneurship track to identify impacts on labor market outcomes one year after graduation. The analysis finds that the entrepreneur…
Transcription of genes in the biosynthetic pathway for fumonisin mycotoxins is epigenetically and differentially regulated in the fungal maize pathog…
2012
ABSTRACT When the fungal pathogen Gibberella moniliformis (anamorph, Fusarium verticillioides ) colonizes maize and maize-based products, it produces class B fumonisin (FB) mycotoxins, which are a significant threat to human and animal health. FB biosynthetic enzymes and accessory proteins are encoded by a set of clustered and cotranscribed genes collectively named FUM, whose molecular regulation is beginning to be unraveled by researchers. FB accumulation correlates with the amount of transcripts from the key FUM genes, FUM1 , FUM21 , and FUM8 . In fungi in general, gene expression is often partially controlled at the chromatin level in secondary metabolism; when this is the case, the deac…
BioTIME: A database of biodiversity time series for the Anthropocene
2018
Abstract Motivation The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community-led open-source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal patterns of biodiversity in the Anthropocene. Main types of variables included The database contains 8,777,413 species abundance records, from assemblages consistently sampled for a minimum of 2 years, which need not necessarily be consecutive. In addition, th…
Repatriation of Debt in the Euro Crisis: Evidence for the Secondary Market Theory
2013
The Euro Crisis has marked a sharp inversion in the process of the European financial integration and, more specifically, a repatriation of countries' debt from foreign to domestic investors. Yet the drivers of the financial fragmentation remain unclear. This paper investigates the empirical patterns in light of competing theories of cross-border portfolio allocation. Three main empirical regularities stand out: i) the repatriation of debt occurred primarily in crisis countries; ii) the repatriation affected mainly public debt; iii) the public debt of crisis countries was reallocated to politically influential countries within the Euro Area. Standard theories of portfolio allocation and hom…
Enseñanza de las ciencias : revista de investigación y experiencias didácticas
2016
Presentamos los resultados de una investigación enfocada a mejorar el aprendizaje de la geometría y la adquisición de destrezas de razonamiento matemático de estudiantes de 2.º año medio de centros de enseñanza secundaria vulnerables de Chile. Se ha diseñado un experimento de enseñanza, con grupos experimental y control, basado en una unidad de enseñanza, diseñada de acuerdo con los niveles y las fases de Van Hiele, y en un pretest y un postest, para evaluar el cambio en el nivel de razonamiento de los estudiantes derivado de la intervención. Los resultados muestran una diferencia significativa, a favor del grupo experimental, en el desarrollo del nivel de razonamiento de los estudiantes. P…
La démocratisation de l'enseignement secondaire sous les deux septennats de François Mitterrand
2004
The democratization of the secondary education in France is a goal followed by the educational politics of the Education Ministers who followed one another during the François Mitterrand presidential area. But all these Ministers, in accordance to their own convictions and the different contexts they faced, have contributed to give this general politics a specific turn. This thesis aims at enlightening the various outlines that the democratization of the secondary education took during this period. It also questions the result of these successive politics.This study in politics history, trying to integrate a broad interdisciplinary field that gives different interpretation hypothesis of the…
'Naughty cylinder' mechanical paradox
2013
The double cone: a mechanical paradox or a geometrical constraint?
2011
In the framework of the Italian National Plan ‘Lauree Scientifiche’ (PLS) in collaboration with secondary schools, we have investigated the mechanical paradox of the double cone. We have calculated the geometric condition for obtaining an upward movement. Based on this result, we have built a mechanical model with a double cone made of aluminum and a couple of wooden rails.
A didactic experiment and model of a flat-plate solar collector
2011
We report on an experiment performed with a home-made flat-plate solar collector, carried out together with high-school students. To explain the experimental results, we propose a model that describes the heating process of the solar collector. The model accounts quantitatively for the experimental data. We suggest that solar-energy topics should be included in school programmes to give students the opportunity to gain experience with solar energy and increase their awareness of the benefits that can be obtained from this remarkable and renewable energy source.