Search results for "Secretions"

showing 10 items of 286 documents

Human Breast Milk NMR Metabolomic Profile across Specific Geographical Locations and Its Association with the Milk Microbiota

2018

The composition of human breast milk is highly variable, and it can be influenced by genetics, diet, lifestyle, and other environmental factors. This study aimed to investigate the impact of geographical location and mode of delivery on the nuclear magnetic resonance spectroscopy (NMR) metabolic profile of breast milk and its relationship with the milk microbiome. Human milk metabolic and microbiota profiles were determined using NMR and 16S rRNA gene sequencing, respectively, in 79 healthy women from Finland, Spain, South Africa, and China. Up to 68 metabolites, including amino acids, oligosaccharides, and fatty acid-associated metabolites, were identified in the milk NMR spectra. The meta…

0301 basic medicinemode of deliveryMetaboliteRiboflavinCarboxylic AcidsOligosaccharidesmicrobiomeBacillusproton nuclear magnetic resonancechemistry.chemical_compoundSouth Africafluids and secretionsPregnancyMetabolitesUreaCaesarean sectionFood scienceAmino AcidsFinlandmetabolitesPhosphocholineNutrition and DieteticsProton nuclear magnetic resonanceMicrobiotaHuman milkfood and beverageshuman milkta3141ActinobacteriaMetabolomeFemalelcsh:Nutrition. Foods and food supplyAdultChinalcsh:TX341-641Breast milkta3111CreatineArticle03 medical and health sciencesYoung AdultMetabolomicsProteobacteriaMetabolomeHumansMetabolomicsMicrobiome030109 nutrition & dieteticsBacteriaMilk HumanCholesterol LDLDelivery Obstetric030104 developmental biologychemistrySpaincaesarean sectionMode of deliveryMicrobiomeBreast feedingFood ScienceNutrients
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Safety and immunomodulatory effects of three probiotic strains isolated from the feces of breast-fed infants in healthy adults: SETOPROB study.

2013

We previously described the isolation and characterization of three probiotic strains from the feces of exclusively breast-fed newborn infants: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. These strains were shown to adhere to intestinal mucus in vitro, to be sensitive to antibiotics and to resist biliary salts and low pH. In the present study, a multicenter, randomized, double-blind, placebo-controlled trial with 100 healthy volunteers in three Spanish cities was carried out to evaluate the tolerance, safety, gut colonization and immunomodulatory effects of these three probiotics. Volunteers underwent a 15-day washout perio…

ARN Bacterianoved/biology.organism_classification_rank.speciesPhysiologylcsh:Medicine:Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::Environment::Ecosystem::Biodiversity::Biota::Microbiota [Medical Subject Headings]law.inventionFecesProbioticAntibioticslawLactobacillus:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Child Nutritional Physiological Phenomena::Infant Nutritional Physiological Phenomena::Breast Feeding [Medical Subject Headings]lcsh:Science:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::RNA::RNA Bacterial [Medical Subject Headings]BifidobacteriumMultidisciplinaryBifidobacterium brevebiologyLacticaseibacillus rhamnosusMicrobiotaHibridación in SituInterleukin-10:Organisms::Bacteria::Gram-Positive Bacteria::Lactobacillales::Lactobacillaceae::Lactobacillus [Medical Subject Headings]Breast FeedingBloodCytokinesFemaleResearch ArticleAdult:Anatomy::Fluids and Secretions::Feces [Medical Subject Headings]Lactobacillus paracasei:Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Clostridium::Clostridium difficile [Medical Subject Headings]Microbiology:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::Nucleic Acid Probes::Oligonucleotide Probes [Medical Subject Headings]Double-Blind MethodLactobacillus rhamnosusHumansImmunologic Factors:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Histocytological Preparation Techniques::Staining and Labeling::In Situ Hybridization [Medical Subject Headings]FecesSafety studiesved/biologyProbioticslcsh:RClostridium difficile:Organisms::Bacteria::Gram-Positive Bacteria::Actinobacteria::Bifidobacterium [Medical Subject Headings]biology.organism_classificationImmunoglobulin ALactobacilluslcsh:QInterleukin-4BifidobacteriumBreast feedingSondas de OligonucleótidosPLoS ONE
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Maternal Microbiota, Cortisol Concentration, and Post-Partum Weight Recovery Are Dependent on Mode of Delivery

2020

© 2020 by the authors.

Adult0301 basic medicineHydrocortisonemicrobiomePhysiologylcsh:TX341-641cortisolBiologydigestive systemArticlecortisol delivery mode microbiome post-partum weight retentionBody Mass Indexdelivery modeFeces03 medical and health sciencesfluids and secretions0302 clinical medicinePregnancyHumansMicrobiomeSalivaSalivary cortisolPost partum2. Zero hunger030219 obstetrics & reproductive medicineNutrition and DieteticsBacteriaCesarean Sectionpost-partum weight retentionVaginal deliveryBody WeightPostpartum Periodfood and beveragesDelivery ObstetricDelivery modeGastrointestinal Microbiome3. Good healthstomatognathic diseases030104 developmental biologyMode of delivery16s rrna gene sequencingFemalelcsh:Nutrition. Foods and food supplyFood ScienceHormoneNutrients
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Meconium microbiota types dominated by lactic acid or enteric bacteria are differentially associated with maternal eczema and respiratory problems in…

2013

Background Culture-dependent methods have shown that meconium, the newborn's first intestinal discharge, is not sterile, but the diversity of bacteria present in this material needs to be further characterized by means of more sensitive molecular techniques. Objective Our aims were to characterize molecularly the meconium microbiota in term infants, to assess whether it contributes to the future microbiota of the infants' gastrointestinal tract, and to evaluate how it relates to lifestyle variables and atopy-related conditions. Methods We applied high-throughput pyrosequencing of the 16S rRNA gene to study the meconium microbiota in twenty term newborns from a Spanish birth cohort. For comp…

AdultDNA BacterialHypersensitivity ImmediateMeconiumImmunologyEczemaBiologyAtopyfluids and secretionsEnterobacteriaceaeMeconiumLactobacillalesPregnancyRisk FactorsRNA Ribosomal 16SmedicineHumansImmunology and AllergyClinical significanceLife StylePhylogenyFecesPregnancyGastrointestinal tractInfant NewbornBacteria Presentmedicine.diseasebiology.organism_classificationIntestinesImmunologyMetagenomeFemaleBacteria
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Maternal diet shapes the breast milk microbiota composition and diversity: impact of mode of delivery and antibiotic exposure

2020

BACKGROUND: Breast milk is a complex biofluid that provides nutrients and bioactive agents, including bacteria, for the development of the infant gut microbiota. However, the impact of maternal diet and other factors, such as mode of delivery and antibiotic exposure, on the breast milk microbiota has yet to be understood. OBJECTIVES: This study aimed to examine the association between maternal diet and breast milk microbiota and to ascertain the potential role of mode of delivery and antibiotic exposure. METHODS: In a cross-sectional study of the MAMI cohort, breast milk microbiota profiling was assessed in 120 samples from healthy mothers by 16S rRNA gene sequencing. Maternal dietary infor…

AdultMale0301 basic medicineBreast milkNutrition and Diseasemedicine.drug_class030106 microbiologyAntibioticsBreastfeedingMedicine (miscellaneous)PhysiologyGut floraBreast milkPlant proteinCohort StudiesAnimal proteinAcademicSubjects/MED0006003 medical and health sciencesfluids and secretionsplant proteinLactobacillusmedicineHumansmaternal dietMaternal dietMicrobiomeBifidobacterium2. Zero hungerNutrition and DieteticsBacteriaMilk HumanbiologyMicrobiotaInfant Newbornfood and beveragesInfantbiology.organism_classificationAnti-Bacterial AgentsDiet3. Good healthCross-Sectional Studies030104 developmental biologyPlant proteinAcademicSubjects/SCI00960breast milkFemaleanimal protein
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Carriage of Enterobacteria Producing Extended-Spectrum β-Lactamases and Composition of the Gut Microbiota in an Amerindian Community

2015

ABSTRACT Epidemiological and individual risk factors for colonization by enterobacteria producing extended-spectrum beta-lactamases (E-ESBL) have been studied extensively, but whether such colonization is associated with significant changes in the composition of the rest of the microbiota is still unknown. To address this issue, we assessed in an isolated Amerindian Guianese community whether intestinal carriage of E-ESBL was associated with specificities in gut microbiota using metagenomic and metatranscriptomic approaches. While the richness of taxa of the active microbiota of carriers was similar to that of noncarriers, the taxa were less homogeneous. In addition, species of four genera,…

AdultMale0301 basic medicinefood.ingredient030106 microbiologyGene ExpressionGut floradigestive systembeta-LactamasesCoprococcusMicrobiologyFeces03 medical and health sciencesfluids and secretionsfoodEnterobacteriaceaeMechanisms of ResistancePhylogeneticsRNA Ribosomal 16SHumansPharmacology (medical)ColonizationPhylogenyAgedPharmacologybiologyEnterobacteriaceae InfectionsSequence Analysis DNAMiddle Agedbiology.organism_classificationParabacteroidesDesulfovibrioEnterobacteriaceaeFrench GuianaGastrointestinal Microbiomestomatognathic diseasesInfectious DiseasesGenes BacterialMetagenomicsCarrier StateIndians North AmericanbacteriaMetagenomeDesulfovibrioFemaleTranscriptomeAntimicrobial Agents and Chemotherapy
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Assessment of the prevalence and characteristics of dens invaginatus in a sample of Turkish Anatolian population.

2009

Objective: The objective of this study was to assess the prevalence and characteristics of dens invaginatus in anterior teeth and to classify the type of dens invaginatus in a sample of Turkish Anatolian population. Study design: A retrospective study was performed using full-mouth periapical and panoramic radiographs of 1012 patients. Maxillary and mandibular anterior teeth were evaluated for the presence and characteristics of dens invaginatus. Statistical evaluation of the presence of dens invaginatus related to gender was performed by the Pearson chi-squared test. Results: Dens invaginatus was observed in 13 out of 1012 subjects and in only maxillary lateral incisors. There were no peri…

AdultMaleAdolescentTurkeyPopulationDentistryDens invaginatusYoung Adultfluids and secretionsstomatognathic systemmedicinePrevalenceHumanseducationChildGeneral DentistryAnterior teethRetrospective StudiesPeriodontitisOrthodonticseducation.field_of_studybusiness.industryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseasedigestive system diseasesDens in Dentestomatognathic diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemalebusinessMedicina oral, patologia oral y cirugia bucal
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Serum concentrations of persistent organic pollutants (POPs) in the inhabitants of a Sicilian city.

2012

Polychlorinated biphenyls (PCBs) and organochlorine pesticides are common environmental contaminants that have been associated with human health problems. OBJECTIVES: To assess serum concentrations of several organochlorine contaminants in general population living in a city with an ancient agricultural tradition and to identify possible exposure sources in Sicily. METHODS: A cross-sectional study was conducted on 101 individuals. Each participant answered a face-to-face questionnaire submitted by well-trained personnel and provided a serum sample which was analyzed for the concentrations of PCBs, HCB, HCHs and DDTs by using gas-chromatography coupled with mass spectrometry. RESULTS: HCB, p…

AdultMaleEnvironmental EngineeringHealth Toxicology and MutagenesisPopulationBiologySettore MED/42 - Igiene Generale E ApplicataGas Chromatography-Mass SpectrometryDDTPolychlorinated biphenylHuman healthfluids and secretionsEnvironmental healthSurveys and QuestionnairesHexachlorobenzeneHydrocarbons ChlorinatedEnvironmental ChemistryHumansCitieseducationSicilyreproductive and urinary physiologyAgedOrganochlorine contaminantsPollutantOrganochlorine pesticideeducation.field_of_studyorganic chemicalsPublic Health Environmental and Occupational HealthPesticide Residuesfood and beveragesOrganochlorine pesticideGeneral MedicineGeneral ChemistrySerum concentrationMiddle AgedPollutionPolychlorinated BiphenylsHuman biomonitoringCross-Sectional StudiesEnvironmental chemistryembryonic structuresEnvironmental PollutantsFemaleEnvironmental MonitoringChemosphere
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Glutathione and glutathione peroxidase in sputum samples of adult patients with cystic fibrosis

2004

AbstractBackground: Reduced glutathione (GSH) is a major antioxidant in the lung. In cystic fibrosis (CF) patients, extracellular GSH levels of lower airways, obtained by bronchoalveolar lavage (BAL), were reported to be lower than non-CF individuals. Methods: Upper airway secretions of stable adult CF patients (29 spontaneous and 13 induced sputum) and non-CF individuals (14 healthy and 12 asthmatics; all induced sputum) were analyzed for total glutathione (i.e. the sum of reduced, GSH, and oxidized, GSSG, forms), GSH and GSSG levels by enzymatic kinetic assay. Results: In CF, both spontaneous and induced sputum samples were comparable in total glutathione levels which were surprisingly hi…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyAntioxidantCystic Fibrosismedicine.medical_treatmentCystic fibrosisAntioxidantschemistry.chemical_compoundInternal medicineExtracellularmedicineUpper airway secretionsHumansPediatrics Perinatology and Child HealthLung inflammatory diseaseschemistry.chemical_classificationGlutathione PeroxidaseLungmedicine.diagnostic_testbusiness.industryGlutathione peroxidaseSputumAntioxidant levelsGlutathionemedicine.diseaseGlutathionerespiratory tract diseasesBronchoalveolar lavagemedicine.anatomical_structureEndocrinologyCross-Sectional StudieschemistryPediatrics Perinatology and Child HealthImmunologySputumFemalemedicine.symptombusinessOxidation-ReductionJournal of Cystic Fibrosis
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A retrospective study of the prevalence and characteristics of dens invaginatus in a sample of the Turkish population.

2012

Objective: The purpose of this study was to assess the prevalence of dens invaginatus and to classify the types of dens invaginatus in a sample of the Turkish population.. Study Design: A retrospective study was performed using periapical and panoramic radiographs of 5355 patients who presented to the Department of Oral Diagnosis and Radiology at the Ondokuz Mayıs University Dentistry Faculty between January 2009 and December 2010. Maxillary and mandibular anterior teeth were evaluated for the presence and characteristics of dens invaginatus. Statistical evaluation of the presence of dens invaginatus related to gender was performed by the Pearson chi-squared test. Results: Dens invaginatus …

AdultMaleTurkish populationAdolescentTurkeyvirusesTurkishLarge populationDentistryOdontologíadigestive systemcomplex mixturesDens invaginatusYoung Adultfluids and secretionsmedicinePrevalenceHumansDens invaginatusOral Diagnosisdens in denteGeneral DentistryAnterior teethAgedRetrospective StudiesPeriodontitisOral Medicine and Pathologybusiness.industryRetrospective cohort studydental anomalyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saluddigestive system diseasesPeriapical lesionDens in DenteOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticlebusinessMedicina oral, patologia oral y cirugia bucal
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