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showing 10 items of 7305 documents

Is cell salvage safe in liver resection? A pilot study

2007

Abstract Study Objective To investigate the quality of cell salvaged (CS) blood in patients undergoing hemihepatectomy (study group) and compare it with CS-blood from aortic surgery (control group). Design Observational study. Setting Operating room in a university hospital. Measurements 6 patients undergoing hemihepatectomy or aortobifemoral bypass with intraoperative blood loss of more than 800 mL. Samples were drawn from the central venous catheter, from the reservoir of a CS recovery system, and from the processed blood in each patient to determine interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor (TNF), complement C3a, and the terminal complement complex C5b-9. Microbiological ana…

medicine.medical_specialtyBlood transfusionmedicine.medical_treatmentCellPilot ProjectsComplement Membrane Attack ComplexResectionBlood Transfusion AutologousmedicineHepatectomyHumansInterleukin-6business.industryInterleukin-8InterleukinBacterial InfectionsInterleukin-10Complement systemSurgeryAnesthesiology and Pain Medicinemedicine.anatomical_structureCytokineComplement C3aErythrocyte TransfusionbusinessAnaerobic exerciseCentral venous catheterJournal of Clinical Anesthesia
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Surgical technique of the supraorbital key-hole craniotomy.

2003

BACKGROUND The enormous development of microsurgical techniques and instrumentation together with preoperative planning using the excellent preoperative diagnostic facilities available, enables neurosurgeons to treat more complicated diseases through smaller and more specific approaches. METHODS The technical details of the supraorbital key-hole craniotomy are described in this article as it has been evolving in our experience for more than 10 years. After an eyebrow skin incision with careful soft tissue dissection and single frontobasal burr-hole trephination, a supraorbital craniotomy is carried out with a diameter of about 1.5 x 2.5 cm. As a real frontolateral approach, the supraorbital…

medicine.medical_specialtyBrain DiseasesSkin incisionbusiness.industrymedicine.medical_treatmentEyebrowSupraorbital craniotomySoft tissueNeurosurgical ProceduresSurgeryDissectionmedicine.anatomical_structuremedicineHumansSurgeryZygomatic archNeurology (clinical)businessOrbitCraniotomyCraniotomyBrain retractionSurgical neurology
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Brain mapping as helpful tool in brain glioma surgical treatment—Toward the “perfect surgery”?

2018

Gliomas are the most common primary malignant brain tumours in adults, representing nearly 80%, with poor prognosis in their high-grade forms. Several variables positively affect the prognosis of patients with high-grade glioma: young age, tumour location, radiological features, recurrence, and the opportunity to perform post-operative adjuvant therapy. Low-grade gliomas are slow-growing brain neoplasms of adolescence and young-adulthood, preferentially involving functional areas, particularly the eloquent ones. It has been demonstrated that early surgery and higher extent rate ensure overall longer survival time regardless of tumour grading, but nowadays, functional preservation that is as…

medicine.medical_specialtyBrain gliomaHigh grade gliomaBrain mappingArticlelcsh:RC321-571Asleep surgery03 medical and health sciences0302 clinical medicineGliomamedicineAdjuvant therapyNeoplasmLow grade gliomaExtent of resectionAwake surgerySurgical treatmentlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrybusiness.industrySettore MED/27 - NeurochirurgiaGeneral NeuroscienceBrain tumourmedicine.diseaseSurgeryAwake surgery030220 oncology & carcinogenesisRadiological weaponBrain mappingbusiness030217 neurology & neurosurgery
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New Hope in Brain Glioma Surgery: The Role of Intraoperative Ultrasound. A Review

2018

Maximal safe resection represents the gold standard for surgery of malignant brain tumors. As regards gross-total resection, accurate localization and precise delineation of the tumor margins are required. Intraoperative diagnostic imaging (Intra-Operative Magnetic Resonance-IOMR, Intra-Operative Computed Tomography-IOCT, Intra-Operative Ultrasound-IOUS) and dyes (fluorescence) have become relevant in brain tumor surgery, allowing for a more radical and safer tumor resection. IOUS guidance for brain tumor surgery is accurate in distinguishing tumor from normal parenchyma, and it allows a real-time intraoperative visualization. We aim to evaluate the role of IOUS in gliomas surgery and to ou…

medicine.medical_specialtyBrain gliomaglioma surgeryTumor resectionBrain tumorReviewintraoperative ultrasound030218 nuclear medicine & medical imagingIntraoperative ultrasoundlcsh:RC321-57103 medical and health sciences0302 clinical medicinemedicineMedical imaginglcsh:Neurosciences. Biological psychiatry. Neuropsychiatrybusiness.industrySettore MED/27 - NeurochirurgiaGeneral NeuroscienceUltrasoundGlioma surgeryGold standard (test)medicine.diseaseSurgeryIOUSbusiness030217 neurology & neurosurgerybrain tumorBrain Sciences
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Endoscopic and surgical resection of T1a/T1b esophageal neoplasms: A systematic review

2013

AIM: To investigate potential therapeutic recommendations for endoscopic and surgical resection of T1a/T1b esophageal neoplasms. METHODS: A thorough search of electronic databases MEDLINE, Embase, Pubmed and Cochrane Library, from 1997 up to January 2011 was performed. An analysis was carried out, pooling the effects of outcomes of 4241 patients enrolled in 80 retrospective studies. For comparisons across studies, each reporting on only one endoscopic method, we used a random effects meta-regression of the log-odds of the outcome of treatment in each study. “Neural networks” as a data mining technique was employed in order to establish a prediction model of lymph node status in superficial …

medicine.medical_specialtyBrief ArticleEsophageal NeoplasmsLymphovascular invasionEndoscopic mucosal resectionRisk AssessmentRisk FactorsmedicineCarcinomaOdds RatioHumansNeoplasm InvasivenessLymph nodeNeoplasm Stagingbusiness.industryCarcinoma in situPatient SelectionCarcinomaGastroenterologyGeneral MedicineEsophageal cancermedicine.diseaseSurgerySquamous carcinomaEsophagectomymedicine.anatomical_structureTreatment OutcomeLymphatic MetastasisAdenocarcinomaRadiologyEsophagoscopyNeoplasm GradingNeoplasm Recurrence Localbusiness
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Impact of margin status on long-term results of liver resection for hepatocellular carcinoma: single-center time-to-recurrence analysis

2020

Occult metastasis from the initial tumor and a de novo second primary hepatocellular carcinoma (HCC) were recognized as the main causes for the onset of early and late HCC recurrence, after liver resection (LR). This study aims to compare the time to recurrence after LR for HCC in which a margin ≤ 1 mm or > 1 mm was achieved. A single-center retrospective study involving 256 patients was conducted from June 2005 to June 2019. HCC patients resected with a radical surgical approach were investigated and stratified into groups A (resection margins ≤ 1 mm) and B (> 1 mm), as measured on final pathologic assessment. Kaplan–Meier estimators were used to estimate the probability of recurrenc…

medicine.medical_specialtyCarcinoma HepatocellularTime FactorsHepatocellular carcinomaHepatocellular carcinoma; Liver resection; Liver transplantation; Margin status; Outcome030230 surgerySingle CenterGastroenterologyGroup BMetastasis03 medical and health sciences0302 clinical medicineInternal medicineHepatocellular carcinoma Liver resection Liver transplantation Margin status Outcome Carcinoma Hepatocellular Liver Neoplasms Neoplasm Recurrence Local Neoplasms Second Primary Time Factors Hepatectomy Margins of ExcisionEpidemiologyHepatectomyHumansMedicineMargin statusPathologicalOutcomeLiver transplantationLiver resectionbusiness.industryProportional hazards modelLiver NeoplasmsMargins of ExcisionNeoplasms Second PrimaryRetrospective cohort studymedicine.diseaseSurgery030220 oncology & carcinogenesisHepatocellular carcinomaSurgeryNeoplasm Recurrence Localbusiness
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Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis

2020

Hepatocellular carcinoma (HCC) is frequently associated with macrovascular invasion of the portal vein or hepatic veins in advanced stages. The accurate diagnosis of macrovascular invasion and the differentiation from bland non-tumoral thrombus has significant clinical and management implications, since it narrows the therapeutic options and it represents a mandatory con-traindication for liver resection or transplantation. The imaging diagnosis remains particularly challenging since the imaging features of HCC with macrovascular invasion may be subtle, espe-cially in lesions showing infiltrative appearance. However, each radiologic imaging modality may provide findings suggesting the prese…

medicine.medical_specialtyCarcinoma Hepatocellularendocrine system diseasesMultimodal Imaging030218 nuclear medicine & medical imagingResection03 medical and health sciences0302 clinical medicinemedicineHepatectomyHumansImaging diagnosisAbdominal ImagingRadiology Nuclear Medicine and imagingcardiovascular diseasesThrombusContraindicationSettore MED/12 - GastroenterologiaPortal Veinbusiness.industryLiver NeoplasmsAdvanced stagemedicine.diseaseTransplantationManagement implicationsHepatocellular carcinomacardiovascular systemRadiologySettore MED/36 - Diagnostica Per Immagini E RadioterapiaCardiology and Cardiovascular MedicinebusinessDiagnostic and Interventional Radiology
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Pathologic response to preoperative transarterial chemoembolization for resectable hepatocellular carcinoma may not predict recurrence after liver re…

2016

medicine.medical_specialtyCarcinoma Hepatocellularmedicine.medical_treatmentTreatment outcomeResection03 medical and health sciences0302 clinical medicineText miningResectable Hepatocellular CarcinomamedicinePathologic ResponseHepatectomyHumansChemoembolization TherapeuticRetrospective StudiesHepatologybusiness.industryLiver NeoplasmsGastroenterologyRetrospective cohort studyTreatment Outcome030220 oncology & carcinogenesis030211 gastroenterology & hepatologyRadiologyHepatectomyNeoplasm Recurrence LocalbusinessHepatobiliarypancreatic diseases international : HBPD INT
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Iatrogenic pulmonary artery dissection in patient with ostium secundum interatrial septum defect

2020

Pulmonary artery dissection is a rare and lethal condition. Few cases are reported in the literature, and most are derived from autopsies. In most cases, pulmonary artery dissection is a complication of chronic pulmonary hypertension leading to pulmonary artery aneurysm but there are other causes. We describe a case of iatrogenic pulmonary artery dissection in an elderly patient with ostium secundum defect. In particular, we describe the role of cardiac magnetic resonance in making this diagnosis and guiding future therapeutic decisions.

medicine.medical_specialtyCardiac magnetic resonanceForamen secundumCase Report030204 cardiovascular system & hematologyOstium secundum defectPulmonary hypertension03 medical and health sciences0302 clinical medicineInternal medicinemedicineIn patient030212 general & internal medicinePulmonary artery dissectionbusiness.industryPulmonary dissectionmedicine.diseasePulmonary hypertensionmedicine.anatomical_structureOstium secundum defectCardiologyCardiology and Cardiovascular MedicinebusinessComplicationCardiac magnetic resonanceInteratrial septum
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Computerized analysis of normal fetal heart rate pattern throughout gestation.

2009

Objective To analyze the evolution of computerized cardiotocography (cCTG) parameters throughout gestation in a large archive of traces from healthy fetuses. Methods This was a cross-sectional study of the first cCTG record from 4412 singleton fetuses with good pregnancy outcome. Normal ranges of cCTG parameters for 25 to 42 weeks were derived from analysis of only one cCTG record per fetus, and the relationship between the parameters and gestational age was investigated. Results Fetal heart rate (FHR) accelerations, short- and long-term variation overall, duration of episodes of high and low variation and variation in high episodes increased with advancing gestation. In contrast, maternal …

medicine.medical_specialtyCardiotocographyGestational AgeUltrasonography PrenatalBasal (phylogenetics)PregnancyHeart ratemedicineHumansRadiology Nuclear Medicine and imagingCardiotocographyComputerized cardiotocographyFetusPregnancyRadiological and Ultrasound Technologymedicine.diagnostic_testObstetricsbusiness.industryPregnancy OutcomeObstetrics and GynecologyGestational ageGeneral MedicineHeart Rate Fetalmedicine.diseaseNomogramsCross-Sectional StudiesReproductive Medicineembryonic structuresGestationFemalebusiness
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