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showing 10 items of 7305 documents

Are primary-care physician practices related to health behaviors likely to reduce social inequalities in health?

2017

Abstract Our objective was to examine patients' health behaviors and the related practices of their primary-care physicians to determine whether physicians' actions might help to reduce the social inequalities in health behaviors among their patients. Fifty-two general practitioners, who were also medical school instructors in the Parisian area, volunteered to participate. A sample of 70 patients (stratified by sex) aged 40–70 years was randomly chosen from each physician's patient panel and asked to complete a questionnaire about their social position and health behaviors: tobacco and alcohol use, diet, physical activity, and participation in breast and cervical cancer screening. Each phys…

AdultMalemedicine.medical_specialtyEpidemiologyHealth Behavior03 medical and health sciencesBreast cancer screening0302 clinical medicineSex FactorsSurveys and QuestionnairesMedicineSocial positionHumansSocial inequality030212 general & internal medicineSocial determinants of healthPractice Patterns Physicians'030505 public healthmedicine.diagnostic_testPrimary Health Carebusiness.industryPublic Health Environmental and Occupational HealthPrimary care physicianMiddle AgedTest (assessment)DisadvantagedCross-Sectional StudiesSocioeconomic FactorsFamily medicineScale (social sciences)Female0305 other medical sciencebusinessPreventive medicine
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Domains of Physical Activity in Relation to Stiffness Index in the General Population.

2021

Background Regular exercise training represents an important modifier of arterial stiffness (AS). Therefore, sex‐specific relations between domains of physical activity (PA; commuting, domestic, and leisure‐time PA, including active sport and occupational PA) with AS were investigated. Methods and Results Stiffness index by digital photoplethysmography was investigated in 12 650 subjects from the GHS (Gutenberg Health Study). Self‐reported PA was evaluated by the “Short Questionnaire to Assess Health‐Enhancing Physical Activity” and reported as activity score peer week, being a combined measure of duration, frequency, and intensity of PA. Multivariable linear regression analysis demonstrat…

AdultMalemedicine.medical_specialtyEpidemiologyPopulationPhysical activityStiffness indexphysical activityPopulation basedRisk Assessmentpopulation basedPhysical medicine and rehabilitationSex FactorsVascular StiffnessRegular exerciseRisk FactorsGermanystiffness indexmedicineHumansHealthy LifestyleProspective StudiesPreventive CardiologyeducationExerciseOriginal Researcheducation.field_of_studybusiness.industryMiddle AgedProtective Factorsmedicine.diseaseLifestylemortalityPrimary PreventionCross-Sectional StudiesCardiovascular DiseasesArterial stiffnessPhysical EnduranceFemaleCardiology and Cardiovascular MedicinebusinessRisk Reduction Behaviorarterial complianceJournal of the American Heart Association
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White-coat hypertension and cardiovascular risk

1995

OBJECTIVE: To compare cardiovascular risk in white-coat hypertensives, normotensives and established hypertensives. METHODS: We studied 61 hypertensive individuals, 27 of whom were white-coat hypertensives, and 35 normotensives. All subjects underwent 24 h noninvasive blood pressure monitoring and Doppler echocardiographic examination of the heart; urine was tested for microalbuminuria and the fundi of the eyes examined for retinopathy. RESULTS: The 24 h as well as the day- and night-time mean systolic blood pressure (SBP) was slightly but significantly higher in white-coat hypertensives than in normotensives; no significant difference was observed in diastolic blood pressure (DBP) between …

AdultMalemedicine.medical_specialtyEpidemiologyWhite coat hypertensionCoronary DiseaseUrineLower riskVentricular Function LeftRisk FactorsInternal medicineMedicineAlbuminuriaHumansPhysician-Patient RelationsEjection fractionbusiness.industryMiddle Agedmedicine.diseaseBlood pressureCross-Sectional StudiesEchocardiographyHypertensionCardiologyAlbuminuriaMicroalbuminuriaFemalemedicine.symptombusinessCardiology and Cardiovascular MedicineStress PsychologicalRetinopathy
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Complications after superficial parotidectomy for pleomorphic adenoma

2018

Background The significance of complications after superficial parotidectomy remains unclear, since prospective studies are lacking. The aim of this study was to evaluate facial nerve dysfunction and other postoperative complications after superficial parotidectomy for pleomorphic adenoma of the superficial lobe and to identify the associated risk factors. Material and Methods Prospective and descriptive clinical study on 79 patients undergoing formal superficial parotidectomy with the modified facelift incision, dissection of the facial nerve and reconstruction with the superficial musculoaponeurotic system flap. Function of the facial nerve using the House-Brackmann scale and the intra- a…

AdultMalemedicine.medical_specialtyFacial ParalysisOral Surgical ProceduresAdenoma PleomorphicPleomorphic adenoma03 medical and health sciencesPostoperative Complications0302 clinical medicineRisk FactorsmedicineHumansParotid GlandLongitudinal StudiesProspective Studies030223 otorhinolaryngologyGeneral DentistryEarlobeAgedParesisAged 80 and overbusiness.industryResearch030206 dentistryMiddle AgedSalivary Gland Neoplasms:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseFacial nerveFacial paralysisParotid glandSurgerystomatognathic diseasesDissectionmedicine.anatomical_structureOtorhinolaryngologySuperficial ParotidectomyUNESCO::CIENCIAS MÉDICASFemaleSurgeryOral Surgerymedicine.symptombusinessMedicina Oral Patología Oral y Cirugia Bucal
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Correlation of Zinc with Oxidative Stress Biomarkers

2015

Hypertension and smoking are related with oxidative stress (OS), which in turn reports on cellular aging. Zinc is an essential element involved in an individual’s physiology. The aim of this study was to evaluate the relation of zinc levels in serum and urine with OS and cellular aging and its effect on the development of hypertension. In a Spanish sample with 1500 individuals, subjects aged 20–59 years were selected, whose zinc intake levels fell within the recommended limits. These individuals were classified according to their smoking habits and hypertensive condition. A positive correlation was found (Pearson’s C = 0.639

AdultMalemedicine.medical_specialtyFarmacologiahypertensionAdolescentCross-sectional studyHealth Toxicology and Mutagenesislcsh:MedicinePhysiologychemistry.chemical_elementUrineZincmedicine.disease_causeArticleYoung Adultchemistry.chemical_compoundRisk FactorsmedicineHumansoxidative stressYoung adultRisk factorCellular SenescenceAgedAged 80 and overGlutathione Disulfidebusiness.industrylcsh:RzincPublic Health Environmental and Occupational HealthMiddle AgedSalut públicaSurgerycellular agingCross-Sectional StudieschemistrySpainGlutathione disulfideFemalebusinessCell agingBiomarkersOxidative stressInternational Journal of Environmental Research and Public Health
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Clinicopathological evaluation and survival of patients with squamous cell carcinoma of the tongue.

2018

Background Early detection of oral cancer is the most effective means of reducing morbidity, complexity, and extent of treatment. This study evaluated the clinicopathological profile of epidermoid carcinoma of the tongue, including treatment and survival. Material and Methods This observational, retrospective cross-sectional study evaluated patients with squamous cell carcinoma of the tongue treated at the Dr. Luiz Antônio Hospital, Natal, Brazil, from January 2001 to December 2011. Survival variables were calculated using the Kaplan-Meier method and compared by log rank tests. Results Of the 412 patients diagnosed in this period, 298 (72.3%) were men; their mean age was 60.5 years, and 69.…

AdultMalemedicine.medical_specialtyGastroenterology03 medical and health sciencesYoung Adult0302 clinical medicineTongueInternal medicineCarcinomaMedicineHumansStage (cooking)General DentistrySurvival rateAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologybusiness.industryResearchCancerRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseTongue NeoplasmsLog-rank testSurvival Ratestomatognathic diseasesmedicine.anatomical_structureCross-Sectional StudiesOtorhinolaryngologyEpidermoid carcinoma030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgeryFemalebusinessMedicina oral, patologia oral y cirugia bucal
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Long-term results of endoscopic resection in early gastric cancer: the Western experience.

2009

Top of pageAbstract OBJECTIVES:  In the West, neither acute nor long-term results of endoscopic resection (ER) for early gastric cancer (EGC) have been reported in large studies. The aim of this study was to prospectively evaluate the efficacy and safety of ER in patients with EGC in a long-term follow-up (FU). METHODS:  From May 1995 to October 2004, 179 patients were referred to our department for endoscopic therapy (ET) of gastric cancer (GC). Of these, 43 patients had intramucosal GC with a diameter of up to 30 mm and underwent ER with curative intent. All patients underwent a strict FU protocol at regular intervals. RESULTS:  Of the 43 patients, 42 fulfilled our low-risk criteria for E…

AdultMalemedicine.medical_specialtyGastroenterologyEndoscopy GastrointestinalStomach NeoplasmsInternal medicinemedicineHumansEndoscopic resectionStomach cancerAgedNot evaluatedAged 80 and overHepatologybusiness.industryGastroenterologyCancerMiddle Agedmedicine.diseaseSurgeryLymphomaEarly Gastric CancerLymphatic systemFemaleLymphbusinessThe American journal of gastroenterology
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Predictive biomarkers for complicated acute appendicitis: A prospective Ecuadorian study.

2020

The aim of the study was to determine the usefulness of known biomarkers as pre-operative predictors of complicated acute appendicitis (CAA) and perforated appendicitis (PA).This was an observational, analytic, cross-sectional, and prospective study at Hospital Teodoro Maldonado Carbo (August 2016-December 2017). Evaluated biomarkers: white blood cells count, neutrophil percentage (N%), neutrophil-to-lymphocyte ratio, glucose, total bilirubin, C-reactive protein, and procalcitonin (PCT). The statistical analysis was performed by means of the area under the receiver operating characteristics (AUROC) curve estimation. Biomarkers' cutoff point was identified using Youden's index. Sensitivity, …

AdultMalemedicine.medical_specialtyGastroenterologySensitivity and SpecificityProcalcitoninLeukocyte CountPredictive Value of TestsInternal medicinemedicineHumansStatistical analysisProspective StudiesProspective cohort studyPredictive biomarkerReceiver operating characteristicbusiness.industrymedicine.diseaseAppendicitisAppendicitisC-Reactive ProteinCross-Sectional StudiesAcute appendicitisSurgeryFemaleCutoff pointEcuadorbusinessBiomarkersCirugia y cirujanos
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Psychometric evaluation of the Generalized Anxiety Disorder Screener GAD-7, based on a large German general population sample.

2017

Abstract Background The Generalized Anxiety Disorder Scales GAD-7 and GAD-2 are instruments for the assessment of anxiety. The aims of this study are to test psychometric properties of these questionnaires, to provide normative values, and to investigate associations with sociodemographic factors, quality of life, psychological variables, and behavioral factors. Methods A German community sample (n=9721) with an age range of 18–80 years was surveyed using the GAD-7 and several other questionnaires. Results Confirmatory factor analyses confirmed the unidimensionality and measurement invariance of the GAD-7 across age and gender. Females were more anxious than males (mean scores: M=4.07 vs. M…

AdultMalemedicine.medical_specialtyGeneralized anxiety disorderAdolescentAlcohol DrinkingPsychometricsmedia_common.quotation_subjectPatient Health Questionnaire03 medical and health sciencesSocial supportYoung Adult0302 clinical medicineQuality of life (healthcare)OptimismAge DistributionRisk FactorsGermanySurveys and QuestionnairesmedicineHumansMeasurement invariance030212 general & internal medicineSex DistributionPsychiatryStress Disorders Traumatic Acutemedia_commonAgedResponse rate (survey)Aged 80 and overSmokingLife satisfactionMiddle Agedmedicine.diseaseAnxiety DisordersPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesSocioeconomic FactorsQuality of LifeAnxietyFemalemedicine.symptomPsychology030217 neurology & neurosurgeryClinical psychologyJournal of affective disorders
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Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fast…

2008

Background: Hypertriglyceridemia is a risk factor for cardiovascular disease. Variation in the apolipoprotein A5 (APOA5) and glucokinase regulatory protein (GCKR) genes has been associated with fasting plasma triacylglycerol. Objective: We investigated the combined effects of the GCKR rs780094C→T, APOA5 −1131T→C, and APOA5 56C→G single nucleotide polymorphisms (SNPs) on fasting triacylglycerol in several independent populations and the response to a high-fat meal and fenofibrate interventions. Design: We used a cross-sectional design to investigate the association with fasting triacylglycerol in 8 populations from America, Asia, and Europe (n = 7730 men and women) and 2 intervention studies…

AdultMalemedicine.medical_specialtyGenotypeGene-Nutrient InteractionsMedicine (miscellaneous)Blood lipidsSingle-nucleotide polymorphismPolymorphism Single NucleotideYoung AdultFenofibrateGene FrequencyRisk FactorsInternal medicineHyperlipidemiamedicineHumansGenetic Predisposition to DiseaseApolipoproteins ATriglyceridesAdaptor Proteins Signal TransducingAgedHypolipidemic AgentsHypertriglyceridemiaNutrition and DieteticsFenofibrateGlucokinase regulatory proteinbiologyGlucokinaseHypertriglyceridemianutritional and metabolic diseasesGenetic VariationFastingMiddle Agedmedicine.diseasePostprandial PeriodDietary FatsPostprandialEndocrinologyCross-Sectional StudiesTreatment OutcomeApolipoprotein A-Vbiology.proteinlipids (amino acids peptides and proteins)Femalemedicine.drugThe American journal of clinical nutrition
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