Search results for "Sedative"

showing 2 items of 62 documents

Sedation During Neurocritical Care

2019

AbstractSedation is an essential therapeutic strategy in the care of neurocritical patients. Intravenous sedative agents are the most widely used, with promising alternatives (dexmedetomidine, ketamine, and volatile agents) to propofol and midazolam arising. Studies designed to evaluate superiority and avoid biases are required. A neurological awakening test is safe in most patients. Potential risks and benefits of limiting deep sedation and daily interruption of sedation in these patients remain unclear. The aim of this review was to report recent clinical evidence on sedation in this subgroup of patients, focusing on its effects on clinical prognosis.

medicine.medical_specialtymedicine.drug_classSedationCritical Care and Intensive Care Medicinelcsh:RD78.3-87.303 medical and health sciences0302 clinical medicine030202 anesthesiologymedicineKetamineDexmedetomidineIntensive care medicinebusiness.industryNeurointensive careneurointensive care unitReview articleneurological wakeup testAnesthesiology and Pain Medicineneurocritical carelcsh:AnesthesiologySedativesedative agentsMidazolamNeurology (clinical)medicine.symptombusinessPropofol030217 neurology & neurosurgerymedicine.drugJournal of Neuroanaesthesiology and Critical Care
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Improved Sedation in Diagnostic and Therapeutic ERCP: Propofol is an Alternative to Midazolam

2000

Background and Study Aims: Adequate sedation of the patient is required for diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). The anesthetic propofol, with its shorter half-life, affording better control, offers an alternative to the benzodiazepine midazolam. The aim of this randomized, controlled, unblinded study was to compare prospectively the quality of sedation under propofol and midazolam in patients undergoing ERCP. Patients and Methods: A total of 80 patients were randomized to sedation with propofol alone (n=40) or midazolam alone (n = 40). Blood pressure, pulse, and oxygen saturation were measured. Midazolam was given by the endoscopist and titrated…

medicine.medical_specialtymedicine.drug_classbusiness.industrySedationGastroenterologylaw.inventionSurgeryHypnoticBlood pressureRandomized controlled triallawAnesthesiaSedativeAnestheticmedicineMidazolammedicine.symptombusinessPropofolmedicine.drugEndoscopy
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