Search results for "Selectivity"

showing 10 items of 1148 documents

ChemInform Abstract: Catalytic Activity of Large-Pore High Si/Al Zeolites: Cracking of Heptane on H-Beta and Dealuminated HY Zeolites

1988

Abstract The catalytic activity, selectivity, catalyst decay, thermal and hydrothermal stability, and acidity of H-Beta and HY zeolites with Si Al ratios of 7.5 and 10, respectively, have been studied during cracking of n-heptane at 450 °C and atmospheric pressure. It has been found that the H-Beta zeolite is more active and decays more slowly than HY. H-Beta presents a higher steric hindrance for dibranched molecules and therefore its open structure should be smaller than that of HY. A lower hydrogen transfer activity and hydrothermal stability is observed for H-Beta in comparison with the corresponding HY.

Steric effectsCrackingHeptanechemistry.chemical_compoundAtmospheric pressurechemistryInorganic chemistryGeneral MedicineZeoliteSelectivityHydrothermal circulationCatalysisChemInform
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Ligand Effects on the Chemoselectivity of Ortho-Metalated Rhodium(II) Catalyzed α-Diazo Ketone Transformations

1997

Rh2(OOCR)2(PC)2 complexes (PC = orthometalated phosphines, OOCR = carboxylates) with very polarizable ligands, such as aromatic rings directly joined to the rhodium atoms, control chemoselectivity in competitive metal carbene transformations of α-diazo ketones. These catalysts have a mixed set of ligands that allows choosing among a big selection of ligands to gradually affect the electronic and steric properties of the catalyst. Their selectivity depends on the electrophilicity of the ligands and the polarizability of the metalated aromatic rings. Thus, Rh2(OOCR)2(PC)2 compounds [PC = (C6H4)P(CH3)(C6H5), (p-CH3C6H3)P(p-CH3C6H4)2, (C6H4)P(C6H5)2; R = C3F7 or CF3] exhibit an exceptional sele…

Steric effectsCyclopropanationStereochemistryLigandOrganic ChemistryAromaticityElectrophilic aromatic substitutionMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryDiazoPhysical and Theoretical ChemistryChemoselectivityCarbeneOrganometallics
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Unveiling the regioselectivity in electrophilic aromatic substitution reactions of deactivated benzenes through molecular electron density theory

2021

The origin of the meta regioselectivity in electrophilic aromatic substitution (EAS) reactions of deactivated benzene derivatives is herein analysed through Molecular Electron Density Theory (MEDT). To this end, the EAS reaction of benzenesulfonic acid with the nitronium NO2+ ion in H2SO4 solution has been studied at the ωB97X-D/6-311G(d,p) level. This reaction takes place through a two-step polar mechanism involving the formation of an unstable cation intermediate. The activation Gibbs free energies associated with the three competitive regioisomeric reaction paths are found in the narrow range of 15.5–18.3 kcal mol−1. By using the Eyring–Polanyi equation a relationship of 18.7 (ortho) : 8…

Steric effectsElectron density010405 organic chemistryRegioselectivityGeneral ChemistryElectrophilic aromatic substitution010402 general chemistryRing (chemistry)01 natural sciencesMedicinal chemistryCatalysis0104 chemical sciencesGibbs free energychemistry.chemical_compoundsymbols.namesakeBenzenesulfonic acidchemistryMaterials ChemistrysymbolsBenzeneNew Journal of Chemistry
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Steric interactions controlling the syn diastereofacial selectivity in the [3 + 2] cycloaddition reaction between acetonitrile oxide and 7-oxanorborn…

2017

A Molecular Electron Density Theory study of the zw-type 32CA reactions of acetonitrile oxide (NO) with two 7-oxanorborn-5-en-2-ones (ONBs) has been performed at the DFT B3LYP/6-31G(d) computational level. These cycloadditions proceed through one-step mechanisms with high activation energies and present low para regio and complete syn diastereofacial selectivities. While the non-polar character of these zw-type 32CA reactions, which is the consequence of the insufficient electrophilic activation of ONBs, according to the analysis of the conceptual DFT reactivity indices, accounts for the high activation energies, and low para regioselectivity, NCI topological analyses at the anti/syn pairs …

Steric effectsElectron density010405 organic chemistryStereochemistryChemistryOrganic ChemistryRegioselectivity010402 general chemistry01 natural sciencesCycloaddition0104 chemical sciencesAcetonitrile oxideComputational chemistryElectrophileReactivity (chemistry)Physical and Theoretical ChemistrySelectivityJournal of Physical Organic Chemistry
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Ethylene oligomerization with 2-hydroxymethyl-5,6,7-trihydroquinolinyl-8-ylideneamine-Ni(II) chlorides

2021

Abstract A series of Ni complexes of the general formula [2-(MeOH)-8-{N(Ar)}C9H8N]NiCl2, where Ar = 2,6-Me2C6H3 in Ni1; 2,6-Et2C6H3 in Ni2; 2,6-i-Pr2C6H3 in Ni3; 2,4,6-Me3C6H2 in Ni4; 2,6-Et2-4-MeC6H2 in Ni5 and 2,4,6-t-Bu3C6H2 in Ni6 has been synthesized and characterized by elemental analysis and IR spectroscopy. On activation with MMAO or Et2AlCl, these complexes showed high activity in ethylene oligomerization, reaching 2.23 × 106 g·mol–1 (Ni) h–1 at 30 °C with the Al/Ni ratio of 5500 and 9.11 × 105 g·mol–1 (Ni) h–1 with the Al/Ni of 800, respectively. Moreover, the content of α-C4 indicated high selectivity exceeding 99% in the Ni/Et2AlCl system. Comparing with the previous report by o…

Steric effectsEthyleneSubstituentInfrared spectroscopy010402 general chemistryCo-catalyst01 natural sciencesBiochemistryMedicinal chemistryInorganic ChemistryMetalchemistry.chemical_compoundSubstituent effectEthylene oligomerizationMaterials ChemistryHydroxymethylSelectivityPhysical and Theoretical ChemistryNickel complexes010405 organic chemistryChemistryLigandOrganic Chemistry0104 chemical sciencesActivityElemental analysisvisual_artvisual_art.visual_art_mediumJournal of Organometallic Chemistry
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Icosahedral carboranes as scaffolds for congested regioselective polyaryl compounds: the distinct distance tuning of C–C and its antipodal B–B

2019

Four-fold aryl substituted o-carborane derivatives with defined patterns of substitution at the antipodal region of the cluster carbon atoms have been achieved. It is proven that this region is congested but lacks steric hindrance. Also, the two antipodal sites Cc–Cc and B9–B12 are affected very distinctly by electron donor substituents.

Steric effectsIcosahedral symmetryAntipodal pointElectron donorCrystal structure010402 general chemistry01 natural sciencesCatalysischemistry.chemical_compoundMaterials ChemistryCluster (physics)BoronO-carboranes010405 organic chemistryChemistryArylMetals and AlloysRegioselectivityGeneral Chemistry3. Good health0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsPharmacophoresCrystallographyCrystal-structureCeramics and CompositesChemical Communications
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The role of fluorine in the stereoselective tandem Aza-Michael addition to acrylamide acceptors: An experimental and theoretical mechanistic study

2007

Aza-Michael additions of alpha-amino esters to fluorinated acceptors take place in a highly stereoselective manner, to give partially modified Psi-[NHCH2]retropeptides incorporating a hydrolytically stable trifluoroalanine mimic. The reaction mechanism has been investigated experimentally and theoretically, in order to explain the effect of the trifluoromethyl group on the reactivity and the origins of the experimentally observed stereocontrol. The reaction is a two-step process, involving a tandem aza-Michael addition followed by a stereoselective hydrogen transfer. Both steps are base-catalyzed. The high level of stereocontrol is the result of a combination of electrostatic interactions a…

Steric effectsModels MolecularReaction mechanismMagnetic Resonance SpectroscopyStereochemistrychemistry.chemical_elementStereoisomerismCatalysisMass Spectrometrychemistry.chemical_compoundComputational chemistrycalculationsReactivity (chemistry)density functionalAcrylamideTrifluoromethyldiastereoselectivity fluorine chemistryOrganic ChemistryStereoisomerismGeneral ChemistryFluorinechemistryFluorineMichael reactionpeptidesStereoselectivityMichael reaction
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Hydrogenation of acetylene-ethylene mixtures on Pd catalysts: study of the surface mechanism by computational approaches. Metal dispersion and cataly…

2000

The hydrogenation mechanism of acetylene–ethylene mixtures on Pd catalysts under different experimental conditions was studied by employing a time-dependent Monte Carlo approach set to use a fixed series of event probabilities. The dependence of the catalyst activity and selectivity on the sizes of the metal particles was simulated at microscopic level and the results, also refined by fitting procedures, suggested proper explanations for the apparent nonuniformity of the related experimental findings. The use of the steric hindrance parameter of the surface species and the available surface energy on the metallic catalyst sites was decisive for reproducing the experimental results.

Steric effectsMonte Carlo methodSurface energyCatalysisMetalchemistry.chemical_compoundAcetylenechemistryvisual_artvisual_art.visual_art_mediumPhysical chemistryPhysics::Chemical PhysicsPhysical and Theoretical ChemistryDispersion (chemistry)SelectivityTheoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta)
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A study of the diels-alder reaction of 3-oxabicyclo[3.3.0]oct-1(5)-ene-2,4-dione with cyclopentadiene and some related dienes

1984

Abstract The reaction of 3-oxabicyclo[3.3.0]oct-l(5)ene-2,4-dione, 2, with cyclopentadiene, 3, 5,5-diethoxycyclopentadiene, 4, and 6,6-dimethylfulvene, 5, is studied. Reaction of 2 and 3 yields the expected endo-adduct, while reaction of 2 and 5 gives a mixture of the endo- and exo-adducts whose ratio is slightly dependent on the reaction conditions. Attractive electrostatic interactions in the transition state leading to the exo-adduct can explain the absence of endo stereoselectivity in the last reaction. Steric factors seem to be responsible for the absence of reaction between 2 and 4. The analysis of the 13C NMR spectra of these adducts and some derived compounds confirms the tentative …

Steric effectsOrder of reactionCyclopentadieneBicyclic moleculeStereochemistryOrganic ChemistryBiochemistryMedicinal chemistryElimination reactionchemistry.chemical_compoundchemistryDrug DiscoveryStereoselectivityEne reactionDiels–Alder reactionTetrahedron
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An ab initio study of the enolboration of 3-pentanone mediated by boron monochlorides L2BCl

2001

Abstract Using ab initio methods at the HF/6-31G∗∗ level, we have studied the mechanism of the enolboration of 3-pentanone mediated by boron monochlorides L2BCl (L=H, methyl and isopropyl) and trimethyl amine. The size of the L group has been found to have a decisive influence on the configuration (E or Z) of the formed boron enolate. Thus, whereas our calculations predict that dimethylboron chloride yields the Z enolate with high stereoselectivity, diisopropylboron chloride is found to yield predominantly the E enolate. The difference in behavior is due mainly to steric features related to the conformational bias of the respective ketone–boron chloride complexes formed reversibly in the fi…

Steric effectsOrganic ChemistryAb initiochemistry.chemical_elementBiochemistryChlorideAldol reactionchemistryAb initio quantum chemistry methodsComputational chemistryDrug DiscoverymedicineStereoselectivityBoronIsopropylmedicine.drugTetrahedron
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