Search results for "Senso"
showing 10 items of 4750 documents
Subthreshold low frequency repetitive transcranial magnetic stimulation selectively decreases facilitation in the motor cortex
2002
Objective: To investigate the modulatory effect of a subthreshold low frequency repetitive transcranial magnetic stimulation (rTMS) train on motor cortex excitability. Methods: The study consisted of two separate experiments. Subjects received a 10 min long subthreshold 1Hz rTMS train. In the first experiment, (single pulse paradigm), cortical excitability was assessed by measuring the amplitude of motor evoked potentials (MEPs) before and after the rTMS train. In the second experiment, a paired pulse paradigm was employed. Results: Corticospinal excitability, as measured by the MEP amplitude, was reduced by the rTMS train (experiment 1), with a significant effect lasting for about 10 min a…
Modulation of input–output curves by low and high frequency repetitive transcranial magnetic stimulation of the motor cortex
2002
Objectives: Exploring the modulatory effects of different frequencies of repetitive transcranial magnetic stimulation (rTMS) on the excitability of the motor cortex as measured by the input-output curve technique (I-O curve). Methods: Sixteen healthy subjects participated in this experiment. On two different sessions, conducted 1 week apart, rTMS was applied either at a frequency of 20 or 1Hz at 90% of individual motor threshold (MT) for a total of 1600 pulses each. Before and after rTMS, the cortical excitability was assessed by measuring MT and the size of motor evoked potentials (MEPs) collected at different intensities of stimulation. Results: The analysis on the whole population showed…
Flicker Defined Form Perimetry in Glaucoma Suspects with Normal Achromatic Visual Fields
2014
To evaluate if repeated flicker-defined form (FDF) perimetry can detect visual field (VF) defects in glaucoma suspects with normal findings in achromatic standard automated perimetry (SAP).Patients with optic nerve heads (ONHs) or retinal nerve fiber layer (RNFL) findings clinically suspicious for glaucoma and normal SAP were enrolled. Patients underwent VF testing with FDF perimetry (Heidelberg Edge Perimetry, HEP) at two consecutive visits (HEP I and HEP II) and confocal scanning laser ophthalmoscopy with the Heidelberg Retina Tomograph (HRT). Abnormal HEP was defined by cluster-point analysis (CPA) and by the HEP specific glaucoma hemi-field test (GHT). Results were compared with an age-…
Olfactory Dysfunction After Head Injury
2008
Objective: To determine the incidence of olfactory dysfunction after head trauma using clinical and radiologic findings, quantitative assessment, and electro-physiologic methods. Participants: A total of 190 patients with head trauma of different severity (n = 32 with mild traumatic brain injury (TBI), n = 94 with signs of moderate TBI, and n = 64 with severe TBI) 6 to 32 months prior to the study. Design: Patients were selected retrospectively, surveyed by telephone (n = 190), and screened for olfactory function with Brief Smell Identification Test (n = 82). Those with olfactory dysfunction were assessed as outpatients using the Sniffin' Sticks (n = 19) and olfactory-evoked potential recor…
Testing the egocentric mirror-rotation hypothesis.
2011
AbstractAlthough observers know about the law of reflection, their intuitive understanding of spatial locations in mirrors is often erroneous. Hecht et al. (2005) proposed a two-stage mirror-rotation hypothesis to explain these misconceptions. The hypothesis involves an egocentric bias to the effect that observers behave as if the mirror surface were rotated by about 2° to be more orthogonal than is the case. We test four variants of the hypothesis, which differ depending on whether the virtual world, the mirror, or both are taken to be rotated. We devised an experimental setup that allowed us to distinguish between these variants. Our results confirm that the virtual world — and only the v…
Model cheese aroma perception is explained not only by in vivo aroma release but also by salivary composition and oral processing parameters
2017
This advance article is part of themed collection: Structure & Sensory.; International audience; The aim of the present paper was to determine, from four model cheeses differing in fat content and firmness and consumed by fourteen well characterised subjects, the respective impacts of in vivo aroma release, bolus rheology, chewing activity, mouth coating and salivary composition on dynamic aroma perception. The originality of the approach is that it considers all the parameters together and is able to evaluate their relative contribution using multi-block partial least square (MB-PLS) regression. The fruity aroma perception of the more hydrophilic compound (ethyl propanoate) was related to …
Schizophrenia and automatic processing: an exploratory study.
1991
This study deals with the schizophrenic deficit as one of automatic processing. To test the idea, a special experimental task was designed on which 21 schizophrenics, 21 depressives, and 21 normal subjects had to complete a series of simple geometric figures. When the subjects had thoroughly learned this activity, another information source, a brief story, was introduced, and the subjects had to pay attention to the story while they did the task. Two dependent variables were considered, execution time and performance. There were no differences among the three groups in the first experimental condition; but in the second condition, when the distractor was introduced, schizophrenics needed m…
Factors limiting performance in a multitone intensity-discrimination task: disentangling non-optimal decision weights and increased internal noise.
2013
To identify factors limiting performance in multitone intensity discrimination, we presented sequences of five pure tones alternating in level between loud (85 dB SPL) and soft (30, 55, or 80 dB SPL). In the "overall-intensity task", listeners detected a level increment on all of the five tones. In the "masking task", the level increment was imposed only on the soft tones, rendering the soft tones targets and loud tones task-irrelevant maskers. Decision weights quantifying the importance of the five tone levels for the decision were estimated using methods of molecular psychophysics. Compatible with previous studies, listeners placed higher weights on the loud tones than on the soft tones i…
Physical capacity in performing daily activities is reduced in scleroderma patients with early lung involvement
2014
BACKGROUND: Patients with systemic sclerosis (SSc) often complain reduced capacity at submaximal exercise; conversely physical capacity in performing daily duties has never been measured in SSc. OBJECTIVES: To evaluate this performance and its correlates, in patients with SSc compared to healthy controls, in a free-living setting. METHODS: Twenty-seven outpatients with stable SSc and 11 controls were recruited. Physical activity was assessed by portable multiple sensor device (SenseWear Armband) worn for at least six days. Physical activity duration (PAD; in minutes) for non-sedentary activities and physical activity level (PAL= total daily energy/resting energy expenditure) per day were ca…
Median and tibial nerve somatosensory evoked potentials: middle-latency components from the vicinity of the secondary somatosensory cortex in humans
1997
The topography of the middle-latency N110 after radial nerve stimulation suggested a generator in SII. To support this hypothesis, we have tried to identify a homologous component in the tibial nerve SEP (somatosensory evoked potential). Evoked potentials following tibial nerve stimulation (motor + sensory threshold) were recorded with 29 electrodes (bandpass 0.5-500 Hz, sampling rate 1000 Hz). For comparison, the median nerve was stimulated at the wrist. Components were identified as peaks in the global field power (GFP). Map series were generated around GFP peaks and amplitudes were measured from electrodes near map maxima. With median nerve stimulation, we recorded a negativity with a ma…