Search results for "Sensory cortex"

showing 3 items of 113 documents

Oxygen and glucose deprivation induces major dysfunction in the somatosensory cortex of the newborn rat

2005

The mechanisms and functional consequences of ischemia-induced injury during perinatal development are poorly understood. Subplate neurons (SPn) play a central role in early cortical development and a pathophysiological impairment of these neurons may have long-term detrimental effects on cortical function. The acute and long-term consequences of combined oxygen and glucose deprivation (OGD) were investigated in SPn and compared with OGD-induced dysfunction of immature layer V pyramidal cortical neurons (PCn) in somatosensory cortical slices from postnatal day (P)0-4 rats. OGD for 50 min followed by a 10-24-h period of normal oxygenation and glucose supply in vitro or in culture led to pron…

medicine.medical_specialtyPatch-Clamp TechniquesTolbutamideIn Vitro TechniquesBiologySomatosensory systemMembrane PotentialsInternal medicineSubplatemedicineExtracellularAnimalsHypoglycemic AgentsMagnesiumEnzyme InhibitorsHypoxiaOuabainNeuronsMembrane potentialCaspase 3General NeuroscienceDose-Response Relationship RadiationDepolarizationSomatosensory CortexHyperpolarization (biology)ImmunohistochemistryElectric StimulationRatsGlucoseNeuroprotective AgentsEndocrinologymedicine.anatomical_structureAnimals Newbornnervous systemApoptosisCaspasesNMDA receptorDizocilpine MaleateEuropean Journal of Neuroscience
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Impact of pharmacological and environmental manipulations on neuronal structural plasticity and dynamics

2017

El sistema nervioso de vertebrados es uno de los más estudiados, aunque peor comprendidos, del organismo de mamíferos. Desde que Ramón y Cajal postuló su teoría celular de este sistema (Ramón y Cajal 1909), la neurona se ha postulado como su unidad funcional. Sin embargo, durante las últimas décadas se ha revolucionado la visión que se tenía de éste. Una de las percepciones más asentadas era que, tras el desarrollo embrionario, el sistema nervioso se mantenía inmutable. Sin embargo, ahora sabemos que diferentes formas de plasticidad gobiernan su adaptación, que son necesarias para importantes procesos del día a día, tales como el aprendizaje y la memoria (Smythies 2002; Berlucchi and Buchte…

nmdamk-801somatosensory cortexhippocampus:CIENCIAS DE LA VIDA::Neurociencias [UNESCO]neuronal dynamics78-dihydroxyflavoneUNESCO::CIENCIAS DE LA VIDA::Fisiología humana ::Neurofisiologíatrkbneuronal plasticityhole-board test2-photon microscopyopen fieldprefrontal cortexinterneuronsfluoxetineUNESCO::CIENCIAS DE LA VIDA::Biología celularnmda receptorsamygdalacranial windowsschizophrenianovel object recognition test:CIENCIAS DE LA VIDA::Biología celular [UNESCO]UNESCO::CIENCIAS DE LA VIDA::Neurociencias:CIENCIAS DE LA VIDA::Fisiología humana ::Neurofisiología [UNESCO]
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Motor action execution in reaction-time movements : Magnetoencephalographic study

2019

OBJECTIVE: Reaction-time movements are internally planned in the brain. Presumably, proactive control in reaction-time movements appears as an inhibitory phase preceding movement execution. We identified the brain activity of reaction-time movements in close proximity to movement onset and compared it with similar self-paced voluntary movements without external command. DESIGN: We recorded 18 healthy participants performing reaction-time and self-paced fast index finger abductions with 306-sensor magnetoencephalography and electromyography. Reaction-time movements were performed as responses to cutaneous electrical stimulation delivered on the hand radial nerve area. Motor field and movemen…

voluntary movementaivokuoriMEGmotor cortexsensory cortexmovement-related cortical fieldmotoriikka
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