Search results for "Server"

Hepatobiliary phase hypointensity predicts progression to hepatocellular carcinoma for intermediate-high risk observations, but not time to progressi…

2020

Purpose: To determine whether hepatobiliary phase hypointensity, enhancing “capsule” and size provide prognostic information regarding the risk of progression to hepatocellular carcinoma (HCC), as well as the time to progression, of intermediate to high risk observations ≥ 10 mm with arterial phase hyperenhancement (APHE). Method: This retrospective dual-institution study included 160 LR-3 and 26 LR-4 observations measuring more than 10 mm and having APHE in 136 patients (mean age [SD], 57 [11] years old). A composite reference standard of pathologic analysis and imaging follow-up was used. The prognostic performance of hepatobiliary phase hypointensity, enhancing “capsule” and size (cut-of…

Role of Cardiac Magnetic Resonance Imaging in the Detection of Cardiac Amyloidosis

2010

Objectives Our aim was to evaluate the role and mechanism of late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) in identifying cardiac amyloidosis (CA) and to investigate associations between LGE and clinical, morphologic, functional, and biochemical features. Background CA can be challenging to diagnose by echocardiography. Recent studies have demonstrated an emerging role for LGE-CMR. Methods LGE-CMR was performed in 120 patients with amyloidosis. Cardiac histology was available in 35 patients. The remaining 85 patients were divided into those with and without echocardiographic evidence of CA. Results Of the 35 patients with histologically verified CA, abnormal LGE was pre…

Design of antitumor drugs targeting c-kit receptor by a new mixed ligand-structure based method

2020

An important challenge, in the medicinal chemistry field, is the research of novel forceful drugs to overcome tumor-acquired resistance. The c-Kit tyrosine kinase receptor (TKR) represents a suitable target for the carcinogenesis control of gastro-intestinal stromal (GIST), leukemia, and mastocytosis tumors; nevertheless, several hotspot mutations of the protein limit the efficacy of a few clinical administered TKRs inhibitors. In this study, a new in silico protocol based on ligand and structure-based combined method is proposed, with the aim to identify a set of new c-Kit inhibitors able to complex c-Kit mutated proteins. A recent and freely available web-server DRUDIT is used for the lig…

On achieving intelligent traffic-aware consolidation of virtual machines in a data center using Learning Automata

2018

Unlike the computational mechanisms of the past many decades, that involved individual (extremely powerful) computers or clusters of machines, cloud computing (CC) is becoming increasingly pertinent and popular. Computing resources such as CPU and storage are becoming cheaper, and the servers themselves are becoming more powerful. This enables clouds to host more virtual machines (VMs). A natural consequence ofthis is that many modern-day data centers experience very high internaltraffic within the data centers themselves. This is, of course, due to the occurrence of servers that belong to the same tenant, communicating between themselves. The problem is accentuated when the VM deployment t…

Robust motion control of nonlinear quadrotor model with wind disturbance observer

2021

This paper focuses on robust wind disturbance rejection for nonlinear quadrotor models. By leveraging on nonlinear unknown observer theory, it proposes a nonlinear dynamic filter that, using sensors already on-board the aircraft, can estimate in real-time wind gust signals in the three dimensions. The wind disturbance is then treated as input to the PD controller for a quick and robust flight pathway in presence of disturbances. With this scheme, the wind disturbance can be precisely estimated online and compensated in real-time. Hence, the quadrotor can successfully reach its desired attitude and position. To show the effective and desired performance of the method, simulation results are …

Energy Efficient Scheduling in Content Distribution Collaborative Mobile Clusters

2020

Most of the existing literatures on green communications aimed to improve the energy efficiency at the base station or data server. However, in order to fully experience high rate broadband multimedia services, prolonging the battery life of user equipment is also critical for the mobile terminals, especially for the smartphone users. In this work, we investigate the problem of designing a content distribution mobile platform named collaborative mobile clusters (CMC) via user cooperation to reduce the energy consumption at the terminal side. Specifically, given numbers of users interested in downloading a common content from the operator, both centralized and distributed user grouping and s…

T-pattern detection and analysis for the discovery of hidden features of behaviour

2018

Abstract Background The behaviour of all living beings consists of hidden patterns in time; consequently, its nature and its underlying dynamics are intrinsically difficult to be perceived and detected by the unaided observer. Method Such a scientific challenge calls for improved means of detection, data handling and analysis. By using a powerful and versatile technique known as T-pattern detection and analysis (TPA) it is possible to unveil hidden relationships among the behavioural events in time. Results TPA is demonstrated to be a solid and versatile tool to study the deep structure of behaviour in different experimental contexts, both in human and non human subjects. Conclusion This re…

Sightseeing in Guidebooks

2007

Efficiency Analysis Of Resource Request Patterns In Classification Of Web Robots And Humans

2018

The paper deals with the problem of classification of Web traffic generated by robots and humans on e-commerce websites. Due to the still growing proliferation and specialization of bots, a large body of research into characterization and recognition of their traffic has been conducted so far. In particular, some approaches to classify bot and human sessions on websites have been proposed in the literature. In this paper we verify and discuss the efficiency of such recently proposed approach, which uses differences in resource request patterns of bots and humans. We reconstructed Web sessions from actual HTTP log data for three different e-commerce sites, varying in the traffic intensity an…

An Analysis of Flash Page Reuse With WOM Codes

2018

Flash memory is prevalent in modern servers and devices. Coupled with the scaling down of flash technology, the popularity of flash memory motivates the search for methods to increase flash reliability and lifetime. Erasures are the dominant cause of flash cell wear, but reducing them is challenging because flash is a write-once medium— memory cells must be erased prior to writing. An approach that has recently received considerable attention relies on write-once memory (WOM) codes, designed to accommodate additional writes on write-once media. However, the techniques proposed for reusing flash pages with WOM codes are limited in their scope. Many focus on the coding theory alone, whereas o…