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showing 10 items of 586 documents

Assessment of tumor microcirculation with dynamic contrast-enhanced MRI in patients with esophageal cancer: initial experience.

2008

PURPOSE: To investigate the feasibility and impact of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) on tumor characterization and response to radiochemotherapy (RCT) in patients with esophageal cancer. MATERIALS AND METHODS: A total of 48 patients underwent DCE-MRI to assess tumor microcirculation based on a two-compartment model function. Effects of RCT on kinetic parameters were studied in 12 patients with squamous cell carcinoma. RESULTS: Tumor microcirculation differs with respect to histological subtype: squamous cell carcinomas showed lower values of amplitude A (leakage space, P = 0.015) and higher contrast agent exchange rates (k(21), P = 0.225) compared with adenoc…

AdultGadolinium DTPAMalemedicine.medical_specialtyEsophageal NeoplasmsUrologyContrast MediaAdenocarcinomaMicrocirculationlaw.inventionRandomized controlled triallawmedicineCarcinomaImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingAgedObserver Variationmedicine.diagnostic_testbusiness.industryMicrocirculationTherapeutic effectMagnetic resonance imagingEsophageal cancerMiddle Agedmedicine.diseaseImage EnhancementMagnetic Resonance ImagingTreatment OutcomeDynamic contrast-enhanced MRICarcinoma Squamous CellFeasibility StudiesHistopathologyFemaleRadiologybusinessJournal of magnetic resonance imaging : JMRI
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Different Pattern of Inflammatory and Atrophic Changes in the Gastric Mucosa of the Greater and Lesser Curvature.

2015


 
 
 
 
 
 Background & Aims: Appropriate biopsy sampling is important for the classification of gastritis, yet the extent of inflammation and atrophy of different regions of the stomach with chronic gastritis have been addressed only in a few studies. The aim of our study was to analyze the inflammatory, atrophic and metaplastic changes in the greater and lesser curvature of the antrum and corpus mucosa.
 Methods: 420 patients undergoing upper endoscopy were enrolled in the study. Four expert gastrointestinal pathologists graded biopsy specimens according to the updated Sydney classification.
 Results: The obtained results showed that the mononu…

AdultGastritis AtrophicMalePathologymedicine.medical_specialtyBiopsyChronic gastritisSeverity of Illness IndexAtrophyPredictive Value of TestsBiopsymedicinePyloric AntrumHumansProspective StudiesAntrumAgedObserver VariationMetaplasiamedicine.diagnostic_testHelicobacter pyloribusiness.industryStomachGastroenterologyIntestinal metaplasiaReproducibility of ResultsAnatomyMiddle Agedmedicine.diseaseCurvatures of the stomachmedicine.anatomical_structureGastric MucosaFemaleGastritismedicine.symptombusinessGranulocytesJournal of gastrointestinal and liver diseases : JGLD
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Intra‐ and interreader reproducibility of PI‐RADSv2: A multireader study

2018

Background The Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) has been in use since 2015; while interreader reproducibility has been studied, there has been a paucity of studies investigating the intrareader reproducibility of PI-RADSv2. Purpose To evaluate both intra- and interreader reproducibility of PI-RADSv2 in the assessment of intraprostatic lesions using multiparametric magnetic resonance imaging (mpMRI). Study type Retrospective. Population/subjects In all, 102 consecutive biopsy-naive patients who underwent prostate MRI and subsequent MR/transrectal ultrasonography (MR/TRUS)-guided biopsy. Field strength/sequences Prostate mpMRI at 3T using endorectal with phased…

AdultImage-Guided BiopsyMaleIntraclass correlationBiopsyPopulationContrast MediaArticle030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineHumansMedicineRadiology Nuclear Medicine and imagingMultiparametric Magnetic Resonance ImagingStage (cooking)educationMultiparametric Magnetic Resonance ImagingAgedRetrospective StudiesUltrasonographyAged 80 and overObserver VariationReproducibilityeducation.field_of_studymedicine.diagnostic_testbusiness.industryProstateProstatic NeoplasmsReproducibility of ResultsMiddle AgedProstate-Specific AntigenReference StandardsMagnetic Resonance ImagingPI-RADSDiffusion Magnetic Resonance ImagingTransrectal ultrasonographybusinessNuclear medicineAlgorithmsKappaJournal of Magnetic Resonance Imaging
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Middle patellar tendon to posterior cruciate ligament (PT–PCL) and normalized PT–PCL: New magnetic resonance indices for tibial tubercle position in …

2018

BACKGROUND To demonstrate whether the distance between the middle point of the patellar tendon and posterior cruciate ligament (PT-PCL) calculated on a single axial MR image could be an alternative measure to tibial tubercle-PCL (TT-PCL) distance for TT lateralization without the need of imaging processing. To show that normalization of PT-PCL (nPT-PCL) against the maximum diameter of the tibial plateau may help to identify patients with patellar instability (PI). METHODS MR scans of 30 patients (13 females, age 32 ± 13 years) with known PI and 60 patients (31 females, age 39 ± 19 years) with no history of PI were reviewed. Two operators calculated TT-PCL, and PT-PCL nPT-PCL. Intraclass cor…

AdultJoint InstabilityMaleAdolescentIntraclass correlationInterobserver reproducibility030218 nuclear medicine & medical imagingPatellofemoral Joint03 medical and health sciences0302 clinical medicineMcNemar's testPatellar LigamentImage Processing Computer-AssistedmedicineHumansOrthopedics and Sports MedicineIn patient030222 orthopedicsTibiamedicine.diagnostic_testReceiver operating characteristicbusiness.industryReproducibility of ResultsMagnetic resonance imagingMiddle AgedMagnetic Resonance ImagingPatellar tendonmedicine.anatomical_structureROC CurvePosterior cruciate ligamentFemalePosterior Cruciate LigamentbusinessNuclear medicineThe Knee
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Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the ev…

2013

Biopsy is still the gold standard for the diagnosis of nonalcoholic steatohepatitis but the definition may vary among pathologists, a drawback especially in evaluation of biopsies for clinical trials. We previously developed a scoring system (steatosis, activity, fibrosis [SAF]) allowing the use of an algorithm (fatty liver inhibition of progression [FLIP]) for the classification of liver injury in morbid obesity. The aim of this study was to determine whether the use of the SAF score and FLIP algorithm can decrease interobserver variations among pathologists. In a first session, pathologists categorized 40 liver biopsies of patients with nonalcoholic fatty liver disease (NAFLD) according t…

AdultLiver CirrhosisMalemedicine.medical_specialtyConcordanceBiopsySettore MED/08 - Anatomia PatologicaSeverity of Illness IndexFibrosisNon-alcoholic Fatty Liver DiseaseInternal medicineSAF steatosis activity fibrosis.Nonalcoholic fatty liver diseaseBiopsyNAS nonalcoholic steatohepatitis activity scoremedicineHumansAgedObserver VariationHepatologymedicine.diagnostic_testbusiness.industryFatty liverGold standard (test)HepatologyMiddle Agedmedicine.diseaseFatty LiverLiverNASH nonalcoholic steatohepatitiDisease ProgressionFemaleNAFLD nonalcoholic fatty liver diseaseSteatosisbusinessAlgorithmAlgorithmsHepatology (Baltimore, Md.)
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Size invariance in visual number discrimination

1991

This study deals with the observer's ability to discriminate the numerosity of two random dot-patterns irrespective of their relative size. One of these two patterns was a reference one that was always composed of 32 dots randomly distributed within a K x K invisible square window (K = 1.92 degrees). The second one was the test pattern with one of the five magnifications (K = 0.64 degrees, 1.28 degrees, 1.92 degrees, 2.56 degrees, 3.20 degrees) and the relative number of dots varied on 11 levels (N = -15, -12, -9, -6, -3, 0, 3, 6, 9, 12, or 15 dots). The observer's task was to indicate which of the two patterns contained more dots. The results show that the stimulus size, as an irrelevant s…

AdultMagnificationExperimental and Cognitive PsychologyStimulus (physiology)Discrimination LearningArts and Humanities (miscellaneous)OrientationPsychophysicsDevelopmental and Educational PsychologyPsychophysicsHumansAttentionDiscrimination learningSize PerceptionMathematicsCommunicationbusiness.industryNumerosity adaptation effectPattern recognitionGeneral MedicineObserver (special relativity)Invariant (physics)Pattern Recognition VisualSize PerceptionArtificial intelligencebusinessPsychological Research
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Intra and inter-raters reliability and agreement of stimulus electrodiagnostic tests with two different electrodes in sedated critically-ill patients

2019

Objective: The aim of the present study was to verify the intra- and inter-rater reliability and agreement of the stimulus electrodiagnostic test (SET) measurements obtained by pen and square elect...

AdultMale030506 rehabilitationmedicine.medical_specialtyPsychometricsElectrodiagnosisCritical IllnessPhysical Therapy Sports Therapy and RehabilitationAnesthesia GeneralStimulus (physiology)AudiologyPolyneuropathies03 medical and health sciences0302 clinical medicinemedicineHumansMuscle SkeletalElectrodesObserver Variationmedicine.diagnostic_testCritically illbusiness.industryElectrodiagnosisReproducibility of ResultsMiddle AgedElectrodiagnostic testFemale0305 other medical sciencebusiness030217 neurology & neurosurgeryPhysiotherapy Theory and Practice
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Cephalometric measurements from 3D reconstructed images compared with conventional 2D images

2011

Abstract Objective: To assess whether the values of different measurements taken on three-dimensional (3D) reconstructions from cone-beam computed tomography (CBCT) are comparable with those taken on two-dimensional (2D) images from conventional lateral cephalometric radiographs (LCRs) and to examine if there are differences between the different types of CBCT software when taking those measurements. Material and Methods: Eight patients were selected who had both an LRC and a CBCT. The 3D reconstructions of each patient in the CBCT were evaluated using two different software packages, NemoCeph 3D and InVivo5. An observer took 10 angular and 3 linear measurements on each of the three types o…

AdultMale2d imagesAdolescentCephalometryRadiographyDentistryOrthodonticsComputed tomographyImage processingMandibleYoung AdultImaging Three-DimensionalImage Processing Computer-AssistedMaxillamedicineHumansNasal BoneSella TurcicaChildMathematicsObserver VariationOrthodonticsmedicine.diagnostic_testPalatebusiness.industryIntraobserver reliabilityReproducibility of ResultsOriginal ArticlesCone-Beam Computed TomographyIncisorFaceMandibular planeFemalebusinessObserver variationSoftwareThe Angle Orthodontist
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The shape of personal space.

2019

The notion of a personal space surrounding one's ego-center is time-honored. However, few attempts have been made to measure the shape of this space. With increasing use of virtual environments, the question has arisen if real-world aspects, such as gender-effects or the shape of personal space, translate to virtual setups. We conducted two experiments, one with real people matched according to body height and level of acquaintance in a large laboratory setting, and one where subjects faced a virtual character, likewise matched to their body height. The first experiment also used a mannequin in place of the second human observer. The second experiment additionally manipulated the perspectiv…

AdultMaleAdolescentBody heightmedia_common.quotation_subjectExperimental and Cognitive PsychologyInterpersonal communicationcomputer.software_genre050105 experimental psychologypsyc03 medical and health sciencesPersonal SpaceYoung Adult0302 clinical medicineSex FactorsArts and Humanities (miscellaneous)Personal spaceDevelopmental and Educational PsychologyHumans0501 psychology and cognitive sciencesConversationInterpersonal Relationsmedia_commonAvatarCommunication05 social sciencesSpace perceptionGeneral MedicineObserver (special relativity)Middle AgedVirtual machineSpace PerceptionFemalePsychologycomputer030217 neurology & neurosurgeryCognitive psychologyActa psychologica
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A Slippery Slope: Estimated Slant of Hills Increases with Distance

2014

The slopes of hills tend to be greatly overestimated. Previous studies have found that slope estimates are significantly greater when estimated verbally than with a proprioceptive measure. It has yet to be determined whether these estimates are made for the entire extent of the slope, or whether the estimates in closest proximity are estimated using a different process. Since some parietal cortex neurons respond differently to objects within arm's reach, short-distance slope estimation may utilize these or analogous neurons. Alternatively, greater implied effort might make longer slopes seem steeper. We determined that both verbal and proprioceptive reports of slope are overestimates that …

AdultMaleAdolescentbusiness.industryDistance PerceptionExperimental and Cognitive PsychologyObserver (special relativity)Slippery slopeProprioceptionGeodesyGazeSensory SystemsJudgmentRandom AllocationYoung AdultOphthalmologyOpticsArtificial IntelligenceSpace PerceptionHumansFemalebusinessDepth perceptionMathematicsPerception
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