Search results for "Sigh"

showing 10 items of 164 documents

Extending the Concept of Knowledge Management into Innovation and New Business Creation

2018

Knowledge management (KM) is a widely-used term in management science of 2000’s. The key essence of KM can be coined e.g. as a “purposeful management of activities and processes for leveraging knowledge to keep and improve competitive positioning by using well individual and collective knowledge resources of the firm and its stakeholders” (CEN, 2004). Majority of the KM discussion and research has focused on recognition, expression and dissemination of knowledge as it manifests itself in the present day of an organization. Research has focused on tangible knowledge artefacts such as Patents, Utility models, Trademarks, Licenses. The processes of creation and maintenance of knowledge are use…

arvonluontiforesighttietämysennakointiinnovationinnovaatiot
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Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling

2021

Bacterial phytochrome photoreceptors usually belong to two-component signaling systems which transmit environmental stimuli to a response regulator through a histidine kinase domain. Phytochromes switch between red light-absorbing and far-red light-absorbing states. Despite exhibiting extensive structural responses during this transition, the model bacteriophytochrome from Deinococcus radiodurans (DrBphP) lacks detectable kinase activity. Here, we resolve this long-standing conundrum by comparatively analyzing the interactions and output activities of DrBphP and a bacteriophytochrome from Agrobacterium fabrum (Agp1). Whereas Agp1 acts as a conventional histidine kinase, we identify DrBphP a…

Histidine KinaseLightPROTEINSScienceAgrobacteriumHISTIDINE KINASESKinasesMolecular Dynamics SimulationPhotoreceptors MicrobialTRANSDUCTIONArticleCYANOBACTERIAL PHYTOCHROME CPH1ACTIVATIONBacterial ProteinsProtein DomainsCRYSTAL-STRUCTUREPHOSPHORYLATIONX-ray crystallographyBacterial structural biologyQREARRANGEMENTSphotoreceptorsAGROBACTERIUM-TUMEFACIENSPhosphoric Monoester HydrolasesINSIGHTSbacterial phytochromesEnzyme mechanismsbacteriaDeinococcus3111 BiomedicineSignal Transduction
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¿Qué pueden aportar las ciencias de la visión al diseño gráfico?

2020

[ES] El diseño gráfico es importante y necesario en el mundo de hoy porque la vista es la principal forma de adquisición de información. Por lo tanto, es lógico pensar que las ciencias de la visión pueden ayudar en la toma de decisiones a nivel de diseño. Comprender conceptos como la agudeza visual, la sensibilidad al contraste, entre otros, contribuirá a optimizar la legibilidad del texto a través de una selección óptima de parámetros tipográficos para formatos impresos y digitales. Además, entender el efecto de las diferentes alteraciones en la visión del color mejorará la accesibilidad del diseño.

Computer scienceVisión del colorPercepció visualPercepciónAccesibilidad050105 experimental psychology03 medical and health sciencesSistema visualPsicofísica0302 clinical medicineDissenyHuman–computer interactionSelection (linguistics)Psychophysics0501 psychology and cognitive sciencesInformation acquisitionColour visionbusiness.industry05 social sciencesColour VisionGraphic designAccessibilityReadabilitySight030221 ophthalmology & optometryPerceptionVisual systembusiness
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A relativistically smeared spectrum in the neutron star X-ray binary 4U 1705−44: looking at the inner accretion disc with X-ray spectroscopy

2009

Iron emission lines at 6.4-6.97 keV, identified with fluorescent Kalpha transitions, are among the strongest discrete features in the X-ray band. These are therefore one of the most powerful probes to infer the properties of the plasma in the innermost part of the accretion disc around a compact object. In this paper we present a recent XMM observation of the X-ray burster 4U 1705-44, where we clearly detect a relativistically smeared iron line at about 6.7 keV, testifying with high statistical significance that the line profile is distorted by high velocity motion in the accretion disc. As expected from disc reflection models, we also find a significant absorption edge at about 8.3 keV; th…

High Energy Astrophysical Phenomena (astro-ph.HE)PhysicsLine-of-sightAstrophysics::High Energy Astrophysical PhenomenaX-ray binaryFOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsRadiusCompact starline: formation line: identification stars: individual: 4U 1705-44 stars: neutron X-ray: binaries X-rays: generalNeutron starSettore FIS/05 - Astronomia E AstrofisicaSpace and Planetary ScienceAstrophysics::Earth and Planetary AstrophysicsEmission spectrumAstrophysics - High Energy Astrophysical PhenomenaSchwarzschild radiusAstrophysics::Galaxy AstrophysicsLine (formation)Monthly Notices of the Royal Astronomical Society
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Scipio Sighele, “La letteratura dei processi”

2012

Republishing and commentary of an excerpt of Scipio Sighele’s “Letteratura tragica”

Sighele Trials LiteratureSettore L-FIL-LET/14 - Critica Letteraria E Letterature Comparate
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MOJAVE: MONITORING OF JETS IN ACTIVE GALACTIC NUCLEI WITH VLBA EXPERIMENTS. VII. BLAZAR JET ACCELERATION

2009

We discuss acceleration measurements for a large sample of extragalactic radio jets from the Monitoring Of Jets in Active Galactic Nuclei with VLBA Experiments (MOJAVE) program, which studies the parsec-scale jet structure and kinematics of a complete, flux-density-limited sample of active galactic nuclei (AGNs). Accelerations are measured from the apparent motion of individual jet features or 'components' which may represent patterns in the jet flow. We find that significant accelerations are common both parallel and perpendicular to the observed component velocities. Parallel accelerations, representing changes in apparent speed, are generally larger than perpendicular acceleration that r…

PhysicsLine-of-sightActive galactic nucleus010308 nuclear & particles physicsAstrophysics::High Energy Astrophysical PhenomenaAstronomy and AstrophysicsQuasarAstrophysicsKinematicsPosition angle01 natural sciencesGalaxy13. Climate actionSpace and Planetary Science0103 physical sciencesPerpendicularBlazar010303 astronomy & astrophysicsThe Astrophysical Journal
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External investigations and disciplinary sanctions against auditors: the impact on audit quality

2015

In this paper, we provide empirical evidence for the impact of disciplinary sanctions imposed on Spanish auditing firms and their engagement partners. The disciplinary sanctions resulted from external investigations, which revealed misapplications of auditing standards. In particular, we evaluate (a) the efficacy of the external supervisory board in identifying low-quality auditors and (b) the effectiveness of the disciplinary system in improving the quality of subsequent statutory audits performed by the sanctioned auditors. We employ two earnings management indicators as proxies for audit quality: loss avoidance through extraordinary items and abnormal accruals. And we compare these measu…

OversightM42AccountingAuditInvestigationsM48Discretionary accrualsAudit qualityJoint auditEarnings managementSanctionsDisciplinary systemsddc:330EconomicsSanctionsFinanceInspectionsEarningsbusiness.industryWalk-through testAuditingQuality assuranceQuality auditEarnings managementInternal auditbusinessGeneral Economics Econometrics and Finance
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Building on Entrepreneurs’ Leadership through ‘Lean’ and Dynamic Performance Management Systems in Small and Micro Firms. Challenges and Missed Oppor…

2014

This paper frames the potential benefits of ‘lean’ and dynamic performance management (PM) systems for small and micro enterprises. In this context, the ‘lean’ attribute is used to characterize a different approach in applying PM to small firms, in respect to larger organizations. In fact, such systems may exploit the entrepreneur’s tacit knowledge and build on leadership, by incorporating individual attributes into organizational routines. Related to small and micro firms, direct experience and case-studies suggest that their sudden crises and demises are often a product of gradual – internal and external – phenomena that entrepreneurs are not enabled to selectively and promptly detect and…

System DynamicLeadershipCase-StudiesEntrepreneurial CapabilitieSettore SECS-P/07 - Economia AziendaleInsight ModelLean and Dynamic Performance ManagementSmall and Micro Firm
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Evidence of Widespread Hot Plasma in a Nonflaring Coronal Active Region from Hinode/X-Ray Telescope

2009

Nanoflares, short and intense heat pulses within spatially unresolved magnetic strands, are now considered a leading candidate to solve the coronal heating problem. However, the frequent occurrence of nanoflares requires that flare-hot plasma be present in the corona at all times. Its detection has proved elusive until now, in part because the intensities are predicted to be very faint. Here, we report on the analysis of an active region observed with five filters by Hinode/X-Ray Telescope (XRT) in 2006 November. We have used the filter ratio method to derive maps of temperature and emission measure (EM) both in soft and hard ratios. These maps are approximate in that the plasma is assumed …

PhysicsLine-of-sightMonte Carlo methodGamma rayAstronomy and AstrophysicsX-ray telescopePlasmaAstrophysicsIsothermal processNanoflareslaw.inventionTelescopeSettore FIS/05 - Astronomia E AstrofisicaSpace and Planetary SciencelawSun: activity Sun: corona Sun: X-rays gamma rays
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Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high educat…

2020

International audience; Cognitive reserve is present in Alzheimer's disease (AD) seniors with high education attainment making them clinically resilient to extended brain neuropathology and neurodegeneration. Here, we tested whether subjective memory complaint (SMC) seniors with AD neuropathology and high education attainment of the prospective INSIGHT-preAD cohort (Paris) may present abnormal eyesclosed resting state posterior electroencephalographic rhythms around individual alpha frequency peak, typically altered in AD patients. The SMC participants negative to amyloid PET AD markers (SMCneg) with high (over low-moderate) education level showed higher posterior alpha 2 power density (pos…

0301 basic medicineMaleAgingpsychology [Alzheimer Disease]alpha rhythms; INSIGHT-preAD study; preclinical Alzheimer's disease (AD); preclinical Alzheimer's neuropathology; resting state EEG rhythms; subjective memory complaint (SMC)physiopathology [Brain]Cohort Studies0302 clinical medicineCognitive ReserveMedicineProspective StudiesCognitive reserveAged 80 and over[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior4. EducationGeneral NeuroscienceNeurodegenerationdiagnosis [Alzheimer Disease]BrainCognitionElectroencephalographyMagnetic Resonance ImagingAlpha Rhythm[SCCO.PSYC]Cognitive science/PsychologyEducational StatusFemale[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]RestAlpha (ethology)NeuropathologyNeuroprotectionphysiopathology [Alzheimer Disease]03 medical and health sciencesRhythmAlzheimer DiseaseMemoryHumansddc:610AgedResting state fMRIbusiness.industry[SCCO.NEUR]Cognitive science/Neurosciencemedicine.disease030104 developmental biologyphysiology [Rest]Positron-Emission TomographyNeurology (clinical)Geriatrics and GerontologybusinessNeuroscience030217 neurology & neurosurgeryDevelopmental Biology
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