Search results for "Signal"

Investigation on the influence of the surface resin rich layer on the thermoelastic signal from different composite laminate lay-ups

2006

This work presents a set of experimental results based on the measured thermoelastic signal from GRP composite coupons adopting different lay-ups. A comparison is made with the thermoelastic signal predicted by two different analytical models: one based on the classical law of the thermoelastic effect for orthotropic materials, and the other based on a novel theory accounting for the presence of a resin layer on the external surface of the composite structure. The composite coupons were designed such to determine a significant difference in the predictions made by the two theoretical models. Experimental results have shown a far better match with the predictions based on the novel theory ac…

Entire reflective object surface structure understanding based on reflection motion estimation

2015

An sub-segmentation method for the reflective surface structure understanding.The use of reflection motion features as spatiotemporal coherence for video segmentation.Straightforward implementation.A building block for object recognition. The presence of reflection on a surface has been a long-standing problem for object recognition since it brings negative effects on object's color, texture and structural information. Because of that, it is not a trivial task to recognize the surface structure affected by the reflection, especially when the object is entirely reflective. Most of the cases, reflection is considered as noise. In this paper, we propose a novel method for entire reflective obj…

A Successive Umbrella Sampling Algorithm to Sample and Overcome Free Energy Barriers

2006

Semiparametric Models with Functional Responses in a Model Assisted Survey Sampling Setting : Model Assisted Estimation of Electricity Consumption Cu…

2010

This work adopts a survey sampling point of view to estimate the mean curve of large databases of functional data. When storage capacities are limited, selecting, with survey techniques a small fraction of the observations is an interesting alternative to signal compression techniques. We propose here to take account of real or multivariate auxiliary information available at a low cost for the whole population, with semiparametric model assisted approaches, in order to improve the accuracy of Horvitz-Thompson estimators of the mean curve. We first estimate the functional principal components with a design based point of view in order to reduce the dimension of the signals and then propose s…

Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism.

2014

Background Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder in which leukemic cells display a reciprocal t(9:22) chromosomal translocation that results in the formation of the chimeric BCR-ABL oncoprotein, with a constitutive tyrosine kinase activity. Consequently, BCR-ABL causes increased proliferation, inhibition of apoptosis, and altered adhesion of leukemic blasts to the bone marrow (BM) microenvironment. It has been well documented that cancer cells can generate their own signals in order to sustain their growth and survival, and recent studies have revealed the role of cancer-derived exosomes in activating signal transduction pathways involved in cancer cell…

An Italian input–output model for the assessment of energy and environmental benefits arising from retrofit actions of buildings

2013

Abstract The paper presents an energy and environmental extended input–output model combined with the life cycle assessment, applied to assess the energy and environmental benefits arising from the Italian policy of tax deduction for energy retrofit actions of buildings. The study allowed to assess the advantages due to the above policy, taking into account both direct and indirect energy saving and avoided CO 2 emissions obtained with the retrofit actions and indirect energy consumption and related CO 2 emissions due to the realization of the above actions. Moreover, the authors defined an original model to assess the indirect rebound effect caused by the energy saving actions. The obtaine…

Karyopherin Msn5 is involved in a novel mechanism controlling the cellular level of cell cycle regulators Cln2 and Swi5

2019

ABSTRACT The yeast β-karyopherin Msn5 controls the SBF cell-cycle transcription factor, responsible for the periodic expression of CLN2 cyclin gene at G1/S, and the nuclear export of Cln2 protein. Here we show that Msn5 regulates Cln2 by an additional mechanism. Inactivation of Msn5 causes a severe reduction in the cellular content of Cln2. This occurs by a post-transcriptional mechanism, since CLN2 mRNA level is not importantly affected in asynchronous cultures. Cln2 stability is not significantly altered in msn5 cells and inactivation of Msn5 causes a reduction in protein level even when Cln2 is stabilized. Therefore, the reduced amount of Cln2 in msn5 cells is mainly due not to a higher …

Regulation of cell cycle transcription factor Swi5 by karyopherin Msn5

2012

AbstractInactivation of S. cerevisiae β-karyopherin Msn5 causes hypersensitivity to the overexpression of mitotic cyclin Clb2 and aggravates growth defects of many mutant strains in mitotic exit, suggesting a connection between Msn5 and mitotic exit. We determined that Msn5 controlled subcellular localization of the mitotic exit transcription factor Swi5, since it was required for Swi5 nuclear export. Msn5 physically interacted with the N-terminal end of Swi5. Inactivation of Msn5 caused a severe reduction in cellular levels of Swi5 protein. This effect occurred by a post-transcriptional mechanism, since SWI5 mRNA levels were not affected. The reduced amount of Swi5 in msn5 mutant cells was…

The S-kernel: A measure of symmetry of objects

2007

In this paper we introduce a new symmetry feature named ''symmetry kernel'' (SK) to support a measure of symmetry. Given any symmetry transform S, SK of a pattern P is the maximal included symmetric sub-set of P for all directions and shifts. We provide a first algorithm to exhibit this kernel where the centre of symmetry is assumed to be the centre of mass. Then we prove that, in any direction, the optimal axis corresponds to the maximal correlation of a pattern with its symmetric version. That leads to a second algorithm. The associated symmetry measure is a modified difference between the respective surfaces of a pattern and its kernel. A series of experiments supports the actual algorit…

CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance

2010

The endocannabinoid system (ECS) plays a critical role in obesity development. The pharmacological blockade of cannabinoid receptor type 1 (CB(1)) has been shown to reduce body weight and to alleviate obesity-related metabolic disorders. An unsolved question is at which anatomical level CB(1) modulates energy balance and the mechanisms involved in its action. Here, we demonstrate that CB(1) receptors expressed in forebrain and sympathetic neurons play a key role in the pathophysiological development of diet-induced obesity. Conditional mutant mice lacking CB(1) expression in neurons known to control energy balance, but not in nonneuronal peripheral organs, displayed a lean phenotype and res…