Search results for "Signal"

showing 10 items of 6924 documents

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

2008

Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …

antisense oligonucleotideCD4-Positive T-LymphocytesAdoptive cell transferT-Lymphocytesanimal cellCell CommunicationInbred C57BLT-Lymphocytes RegulatoryTransgenicMiceregulatory T lymphocyteCrohn DiseaseTransforming Growth Factor betamononuclear cellRAG1 proteinIntestinal MucosaenteritisCells CulturedMice KnockoutSettore MED/12 - GastroenterologiaCulturedintegumentary systemmedicine.diagnostic_testarticleGastroenterologyInterleukinhemic and immune systemsT helper cellColitisRegulatoryUp-Regulationmedicine.anatomical_structurepriority journalgamma interferonSignal TransductionRegulatory T cellColonCellsKnockoutanimal experimentinterleukin 6chemical and pharmacologic phenomenaMice TransgenicBiologyinterleukin 2Recombination-activating geneFlow cytometryProinflammatory cytokineSmad7 ProteinmedicineAnimalsHumanscontrolled studyhumanlamina propriamouseCell ProliferationHomeodomain ProteinsCD4+ T lymphocytenonhumanHepatologyAnimalflow cytometryhuman cellanimal cell culturetransgenic mouseMice Inbred C57BLDisease Models Animalantisense oligonucleotide; gamma interferon; interleukin 17; interleukin 2; interleukin 6; RAG1 protein; Smad7 protein; animal cell; animal cell culture; animal experiment; article; CD4+ T lymphocyte; cell proliferation; colitis; controlled study; enteritis; flow cytometry; human; human cell; knockout mouse; lamina propria; mononuclear cell; mouse; nonhuman; priority journal; regulatory T lymphocyte; transgenic mouse; Animals; CD4-Positive T-Lymphocytes; Cell Communication; Cell Proliferation; Cells Cultured; Colitis; Colon; Crohn Disease; Disease Models Animal; Homeodomain Proteins; Humans; Intestinal Mucosa; Mice; Mice Inbred C57BL; Mice Knockout; Mice Transgenic; Signal Transduction; Smad7 Protein; T-Lymphocytes Regulatory; Transforming Growth Factor beta; Up-RegulationDisease ModelsImmunologyinterleukin 17knockout mouseTransforming growth factorGastroenterology
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Kaon-proton strong interaction at low relative momentum via femtoscopy in Pb-Pb collisions at the LHC

2021

Physics letters / B 822, 136708 (2021). doi:10.1016/j.physletb.2021.136708

atom: exoticheavy ion: scatteringnucleon: paircorrelation [momentum]exoticheavy ion scatteringmomentum correlationmeasurement methodsHadron01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)effective field theoryALICE[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]effective field theory: chiralNuclear Experiment (nucl-ex)Nuclear ExperimentNuclear Experimentchiral [effective field theory]effective field theory chiralPhysicsatom exoticSPECTROSCOPYatomstrong interactionPhysicsnucleontwo-particleheavy ion3. Good healthCERN LHC Collkinematicsforce CoulombScattering theoryNucleonforceCoulomb [force]Particle Physics - ExperimentParticle physicsNuclear and High Energy Physicsstrong interaction [K p]QC1-999FOS: Physical sciencesmomentum[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]530K p: strong interaction ; heavy ion: scattering ; momentum: correlation ; force: Coulomb ; effective field theory: chiral ; atom: exotic ; nucleon: pair ; heavy ion scattering ; momentum correlation ; force Coulomb ; effective field theory chiral ; atom exotic ; nucleon pair ; CERN LHC Coll ; two-particle ; measurement methods ; sensitivity ; strong interaction ; ALICE ; kinematics ; TeV ; scattering length ; experimental results ; 5020 GeV-cms/nucleon ; hadron114 Physical sciencesscattering [heavy ion]0103 physical sciencesTeVSCATTERINGNuclear Physics - Experimentddc:5305020 GeV-cms/nucleonSensitivity (control systems)010306 general physicsexotic [atom]Exotic atomK p: strong interaction010308 nuclear & particles physicsScatteringforce: Coulombpairpair [nucleon]momentum: correlationScattering lengthHeavy Ions ExperimentsLOW-ENERGY K; DA-PHI-NE; SCATTERING; SPECTROSCOPYsensitivityLOW-ENERGY KchiralALICE heavy-ion collisions nuclear physicscorrelationscattering lengthCoulombHigh Energy Physics::ExperimenthadronDA-PHI-NEnucleon pairEnergy (signal processing)experimental results
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Anomaly Detection and Classification of Household Electricity Data : A Time Window and Multilayer Hierarchical Network Approach

2022

With the increasing popularity of the smart grid, huge volumes of data are gathered from numerous sensors. How to classify, store, and analyze massive datasets to facilitate the development of the smart grid has recently attracted much attention. In particular, with the popularity of household smart meters and electricity monitoring sensors, a large amount of data can be obtained to analyze household electricity usage so as to better diagnose the leakage and theft behaviors, identify man-made tampering and data fraud, and detect powerline loss. In this paper, the time window method is first proposed to obtain the features and potential periodicity of household electricity data. Combining th…

autoencoderMains electricityComputer Networks and CommunicationsComputer sciencemultilayer hierarchical networkkotitaloudetverkot (järjestelmät)computer.software_genreanomaly detectionComputer Science Applicationshousehold electricitysähkönkulutussähködataclassificationHardware and ArchitectureTime windowspoikkeavuusSignal ProcessingAnomaly detectionData miningcomputerNetwork approachfeedforward networkInformation Systems
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Colorimetric Characterization of a Positive Film Scanner Using an Extremely Reduced Training Data Set

2011

International audience; In this work, we address the problem of having an accurate colorimetric characterization of a scanner for traditional posi- tive film in order to guarantee the accuracy of the color informa- tion during the digitization of a movie. The scanning of a posi- tive film is not an usual task, however it can happen for cultural heritage purpose. Art-movies, are often created and stored as positive-film in museums. One of the problems one can face for a colorimetric characterization is to have a reasonable number of measurements from an item. In this work we succeeded in having a reasonable accuracy with just a few number of measurement (typically 4 to 7 ∆Ea∗b units with 2 t…

avant-garde cinema[ INFO.INFO-TS ] Computer Science [cs]/Signal and Image Processing[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing[INFO.INFO-TS] Computer Science [cs]/Signal and Image Processingreduce data setScanner colorimetric characterization[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processingfilm[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing[SPI.SIGNAL] Engineering Sciences [physics]/Signal and Image processing
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The increase in maternal expression of axin1 and axin2 contribute to the zebrafish mutant ichabod ventralized phenotype.

2014

β-Catenin is a central effector of the Wnt pathway and one of the players in Ca(+)-dependent cell-cell adhesion. While many wnts are present and expressed in vertebrates, only one β-catenin exists in the majority of the organisms. One intriguing exception is zebrafish that carries two genes for β-catenin. The maternal recessive mutation ichabod presents very low levels of β-catenin2 that in turn affects dorsal axis formation, suggesting that β-catenin1 is incapable to compensate for β-catenin2 loss and raising the question of whether these two β-catenins may have differential roles during early axis specification. Here we identify a specific antibody that can discriminate selectively for β-…

axin1axin2zebrafish mutant ichabodMessengerEmbryonic DevelopmentBiochemistryBETA-CATENINAxin2-RGS DOMAINAxin ProteinAntibody SpecificitySettore BIO/10 - BiochimicaAnimalsAxin2-RGS DOMAIN; AXIS FORMATION; BETA-CATENIN; Wnt signaling; ZEBRAFISH; Animals; Antibody Specificity; Axin Protein; Blastula; Cell Nucleus; Embryonic Development; Female; Gene Expression Regulation Developmental; Genes Dominant; Immunohistochemistry; Lithium Chloride; Mutation; Phenotype; Protein Stability; Protein Transport; RNA Messenger; Signal Transduction; Up-Regulation; Zebrafish; Zebrafish Proteins; beta Catenin; Biochemistry; Cell Biology; Molecular BiologyDevelopmentalDominantRNA MessengerMolecular BiologyZebrafishbeta CateninGenes DominantAXIS FORMATIONCell NucleusProtein StabilityGene Expression Regulation DevelopmentalCell BiologyBlastulaZebrafish ProteinsWnt signalingImmunohistochemistryUp-RegulationProtein TransportPhenotypeGene Expression RegulationGenesMutationRNAFemaleLithium ChlorideSignal Transduction
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Measurement of light-by-light scattering and search for axion-like particles with 2.2 nb−1 of Pb+Pb data with the ATLAS detector

2021

We thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; ANID, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS and CEA-DRF/IRFU, France; SRNSFG, Georgia; BMBF, HGF and MPG, Germany; GSRT, Greece; RGC and Hong Kong SAR, China; ISF and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Mor…

axion: mass: lower limit:Kjerne- og elementærpartikkelfysikk: 431 [VDP]heavy ion: scatteringmeasured [channel cross section]transverse energy [photon]QC770-798transverse momentum dependence01 natural scienceschannel cross section: upper limitmass: lower limit [axion]High Energy Physics - ExperimentSubatomär fysikHigh Energy Physics - Experiment (hep-ex)Hadron-Hadron scattering (experiments)Subatomic Physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Invariant massNuclear Experiment (nucl-ex)Nuclear ExperimentNuclear ExperimentQCPhysicsphoton: transverse energySettore FIS/01Large Hadron ColliderLuminosity (scattering theory)upper limit [channel cross section]ATLASangular dependence:Nuclear and elementary particle physics: 431 [VDP]CERN LHC CollPseudorapidityaxion-like particlesProduction (computer science)channel cross section: measuredParticle Physics - ExperimentParticle physicsNuclear and High Energy Physics530 PhysicsFOS: Physical sciences[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]transverse momentumplanarityRelativistic heavy ionsAcoplanarity530differential cross section: measuredscattering [heavy ion]measured [differential cross section]Nuclear and particle physics. Atomic energy. Radioactivity0103 physical sciencesddc:530Nuclear Physics - Experimentlcsh:Nuclear and particle physics. Atomic energy. Radioactivity5020 GeV-cms/nucleonHigh Energy PhysicsLHC Particle Physics Lead-lead collisions010306 general physicsCiencias Exactastwo-photon [mass spectrum]leadrapidity [photon]Scattering010308 nuclear & particles physicsphoton photon: scatteringFísicaphoton: rapidityExperimental High Energy PhysicsS029AXPscattering [photon photon]lcsh:QC770-798Energy (signal processing)mass spectrum: two-photonexperimental resultsThe Journal of High Energy Physics
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Quality, Reliability, Security and Robustness in Heterogeneous Systems

2020

This book constitutes the refereed post-conference proceedings of the 15th EAI International Conference on Quality, Reliability, Security and Robustness in Heterogeneous Networks, QShine 2019, held in Shenzhen, China, in November 2019. The 16 revised full papers were carefully reviewed and selected from 55 submissions. The papers are organized thematically in tracks, starting with mobile systems, cloud resource management and scheduling, machine learning, telecommunication systems, and network management.

bandwidthartificial intelligenceinternetmobiledevicesrouterstelecommunication networksdata communication systemscomputing mobileWorld Wide Webroutingsensorcomputer networkstelecommunication trafficdata securitysignal processingwireless sensor networksnetworks sensorswireless telecommunication systems
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Data from: How ants acclimate: impact of climatic conditions on the cuticular hydrocarbon profile

2018

1. Organisms from temperate zones are exposed to seasonal changes and must be able to cope with a wide range of climatic conditions. Especially ectotherms, including insects, are at risk to desiccate under dry and warm conditions, the more so given the changing climate. 2. To adjust to current conditions, organisms acclimate through changes in physiology, morphology and/or behaviour. Insects protect themselves against desiccation through a layer of cuticular hydrocarbons (CHC) on their body surface. Hence, acclimation may also affect the CHC profile, changing their waterproofing capacity under different climatic conditions. 3. Here, we investigated the acclimation response of two Temnothora…

beneficial acclimation hypothesismedicine and health caredesiccationTemnothorax ambiguusTemnothorax longispinosusLife SciencesMedicineMyrmicinaesocial insect castescommunication signals
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Costs and benefits of plant allelochemicals in herbivore diet in a multi enemy world

2015

Sequestration of plant defensive chemicals by herbivorous insects is a way of defending themselves against their natural enemies. Such herbivores have repeatedly evolved bright colours to advertise their unpalatability to predators, i.e. they are aposematic. This often comes with a cost. In this study, we examined the costs and benefits of sequestration of iridoid glycosides (IGs) by the generalist aposematic herbivore, the wood tiger moth, Parasemia plantaginis. We also asked whether the defence against one enemy (a predator) is also effective against another (a parasitoid). We found that the larvae excrete most of the IGs and only small amounts are found in the larvae. Nevertheless, the a…

bio assaywarning signalheinäratamoiridoid glycosidescotesia villana
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Decoupled Acoustic and Visual Components in the Multimodal Signals of the Common Cuckoo (Cuculus canorus)

2021

Because of its parasitic habits, reproduction costs of the common cuckoo (Cuculus canorus) are mostly spent in pre-laying activities. Female costs are limited to searching host nests and laying eggs, whereas, males spend time in performing intense vocal displays, possibly with territorial purpose. This last aspect, together with a sexual plumage dimorphism, points to both intra- and inter-sexual selections operating within this species. One element triggering sexual selection is a differential fitness accrued by different phenotypes. Before analyzing possible sexual selection mechanisms operating in cuckoos, it is therefore necessary to verify whether there is a variability among male secon…

bioacousticsEcologyEvolutioncuckooQH359-425multimodal signalssexual selectionbioacoustics; courtship rituals; cuckoo; multimodal signals; sexual selectioncuckoo; sexual selection; courtship rituals; bioacoustics; multimodal signalsQH540-549.5courtship rituals
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