Search results for "Significant difference"
showing 10 items of 337 documents
Spatial Distribution of Ethylene Production by Individual Needles Along a Shoot ofPinus sylvestrisL.: Relationship with Peroxidase Activity
1998
Spatial distribution of ethylene production by individual current year needles and the relationship with peroxidase activity was studied along a shoot of Scots pine (Pinus sylvestrisL.). Much variation in ethylene production between and within individual seedlings was found. There was a significant difference in mean intensity of ethylene production between orthostichies within individual seedlings. The capacity of individual needles to convert 1-aminocyclopropane-1-carboxylic acid (ACC) to ethylene did not correlate with the basal rate of ethylene production. Mean ethylene production intensity by orthostichies correlated positively with mean peroxidase activity. A positive correlation betw…
Antimicrobial, mechanical and biocompatibility analysis of chlorhexidine digluconate-modified cements
2019
Background The focus of this study was to evaluate the antimicrobial, mechanical properties and biocompatibility of glass ionomer (GICs) modified by Chlorhexidine (CHX). Material and Methods For biocompatibility, 105 male Wistar rats were used, divided into 7 groups (n=15): Group C (Control,Polyethylene), Groups M, M10, M18, and Groups RL, RL10, RL18 (M-Meron and RL-Riva Luting: conventional, and modified with 10%, and 18% CHX, respectively). The tissues were analyzed under optical microscope for different cellular events and time intervals. Antibacterial effect and Shear Bond Strength Test (SBST) were also analyzed. Biocompatibility was analyzed by the Kruskal-Wallis and Dunn tests; SBST o…
Microtomographic reconstruction of mandibular defects treated with xenografts and collagen-based membranes:a pre-clinical minipig model
2021
Background The goal of this study was to evaluate hard tissue response following guided bone regeneration using commercially available bovine bone grafts and collagen membranes; bilayer collagen membrane and porcine pericardium-based membrane, by means of a non-destructive three-dimensional (3D) computerized volumetric analysis following microtomography reconstruction. Material and Methods Bone regenerative properties of various bovine bone graft materials were evaluated in the Göttingen minipig model. Two standardized intraosseous defects (15mm x 8mm x 8mm) were created bilaterally of the mandible of eighteen animals (n=72 defects). Groups were nested within the same subject and randomly d…
Shaping ability of Mtwo and Twisted File rotary systems in curved root canals
2012
Objective: To compare the straightening of root canal curvature, the apical transportation, the loss of working length and the working time using two rotary systems. Study design: Sixty buccal root canals with angles of curvature between 30 to 99º were instrumented with Mtwo and Twisted File rotary instruments. A series of pre- and post-operative radiographs were superimposed to determine the straightening of root canal curvature and apical transportation. The loss of working length and working time were also calculated. Results: All data were analyzed by means of the Student´s t-test and Mann-Whitney U-test. No statistically significant differences in the straightening of root canal curvat…
Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic…
2014
Background: The prognostic impact of segmental chromosome alterations (SCAs) in children older than 1 year, diagnosed with localised unresectable neuroblastoma (NB) without MYCN amplification enrolled in the European Unresectable Neuroblastoma (EUNB) protocol is still to be clarified, while, for other group of patients, the presence of SCAs is associated with poor prognosis. Methods: To understand the role of SCAs we performed multilocus/pangenomic analysis of 98 tumour samples from patients enrolled in the EUNB protocol. Results: Age at diagnosis was categorised into two groups using 18 months as the age cutoff. Significant difference in the presence of SCAs was seen in tumours of patients…
Preexisting musculoskeletal burden and its development under letrozole treatment in early breast cancer patients
2019
One of the most common adverse events (AEs) occurring during treatment with aromatase inhibitors (AIs) is musculoskeletal pain. The aim of our study was to analyze the influence of preexisting muscle/limb pain and joint pain on the development of AI-induced musculoskeletal AEs. Women eligible for upfront adjuvant endocrine therapy with letrozole were included in the PreFace study, a multicenter phase IV trial. During the first treatment year, they were asked to record musculoskeletal AEs monthly by answering questions regarding pain symptoms and rating the pain intensity on a numeric rating scale from 0 (no pain) to 10 (very strong pain). Pain values were compared using nonparametric statis…
In the literature: May 2016
2016
Radiotherapy as single modality was considered the standard of care for low-grade gliomas, a mixed population of low proliferative tumours including oligodendrogliomas, oligoastrocytomas and grade 2 astrocytomas. However, a recently reported trial in the New England Journal of Medicine indicates1 that the addition of procarbacine, lomustine (CCNU) and vincristine, a combination known by its acronym, PCV, significantly prolongs survival in patients with low-grade glioma. When this trial was initially reported in 2012, after a median follow-up of almost 6 years, according to the estimated number of events needed to analyse the results, a significant difference in progression-free survival (PF…
A quality improvement study on the reduction of central venous catheter-associated bloodstream infections by use of self-disinfecting venous access c…
2020
Background Contamination of the catheter hub is an important source of central line-associated bloodstream infections (CLABSI); catheter hub caps incorporating a 70% isopropyl alcohol aim are designed to reduce contamination and hence CLABSI rates. Supporting data in high-risk hematological and oncological patients on the clinical effectiveness of this approach are sparse. Methods We conducted a before-after single center study accompanying the introduction of such caps at our department. Retrospective data from the year prior to the introduction were compared to 1 year of prospective data. Results The control and antiseptic barrier cap (ABC) groups consisted of 309 and 289 patients present…
Influence of thickness and translucency of lithium disilicate ceramic on degree of conversion of resinous materials
2020
Background In this study was assessed the degree of conversion (DC) of amine-free resin cements light cured through lithium disilicate-reinforced ceramics at different thicknesses and translucency. Material and Methods Specimens were divided into 21 groups (n = 5) according to luting agent used: Variolink Esthetic LC (Light shade), RelyX Ultimate (A1 shade), and Filtek Z350 XT Flow (A1 shade); the ceramic translucency: low (LT) and high (HT); and the ceramic thickness: no ceramic (control), 0.5 mm, 1 mm, and 2 mm. A Teflon mold with (5 x 5 x 0.5 mm) was used to standardize the cement and over it the ceramic block from each group was placed. Set was cured using a polywave LED light (1200 mW/…
Shear bond strength of debonded ceramic restorations re-cemented by means of a cleaning and retreatment protocol
2019
Background As there is no standard method for re-cementing debonded partial ceramic restorations, the aim of this study was to evaluate the use of a non-invasive thermal protocol for cleaning and retreatment, and to study its influence on shear bond strength. Material and methods Twenty ceramic samples (IPS e.max CAD®) were bonded to composite cement cylinders and underwent a shear bond strength test (G1, n=20). A second group was created (G2, n=20), representing debonded restorations. To simulate debonding, the samples were artificially contaminated with composite cement. After debonding, these underwent a thermal protocol to remove remaining adhesive. After rebonding to the composite ceme…