Search results for "Simulation."

A novel process-based model of microbial growth: self-inhibition in Saccharomyces cerevisiae aerobic fed-batch cultures

2015

Microbial population dynamics in bioreactors depend on both nutrients availability and changes in the growth environment. Research is still ongoing on the optimization of bioreactor yields focusing on the increase of the maximum achievable cell density. A new process-based model is proposed to describe the aerobic growth of Saccharomyces cerevisiae cultured on glucose as carbon and energy source. The model considers the main metabolic routes of glucose assimilation (fermentation to ethanol and respiration) and the occurrence of inhibition due to the accumulation of both ethanol and other self-produced toxic compounds in the medium. Model simulations reproduced data from classic and new expe…

Assessment of Salmonella and Listeria monocytogenes level in ready-to-cook poultry meat: Effect of various high pressure treatments and potassium lac…

2014

International audience; The objective of this study was to develop a probabilistic model in order to determine the contamination level of Salmonella and Listeria monocytogenes in ready-to-cook poultry meat, after a high pressure (HP) treatment. The model included four steps: i) Reception of raw meat materials, mincing and mixing meat, ii) Partitioning and packaging into 200-g modified atmosphere packs, iii) High pressure treatment of the meat, and iv) Storage in chilled conditions until the end of the shelf-life. The model excluded the cooking step and consumption at consumer's home as cooking practices and heating times are highly variable. The initial contamination level of Salmonella and…

Poly-sarcosine and poly(ethylene-glycol) interactions with proteins investigated using molecular dynamics simulations

2018

Nanoparticles coated with hydrophilic polymers often show a reduction in unspecific interactions with the biological environment, which improves their biocompatibility. The molecular determinants of this reduction are not very well understood yet, and their knowledge may help improving nanoparticle design. Here we address, using molecular dynamics simulations, the interactions of human serum albumin, the most abundant serum protein, with two promising hydrophilic polymers used for the coating of therapeutic nanoparticles, poly(ethylene-glycol) and poly-sarcosine. By simulating the protein immersed in a polymer-water mixture, we show that the two polymers have a very similar affinity for the…

Quantifying unpredictability: A multiple-model approach based on satellite imagery data from Mediterranean ponds.

2017

Fluctuations in environmental parameters are increasingly being recognized as essential features of any habitat. The quantification of whether environmental fluctuations are prevalently predictable or unpredictable is remarkably relevant to understanding the evolutionary responses of organisms. However, when characterizing the relevant features of natural habitats, ecologists typically face two problems: (1) gathering long-term data and (2) handling the hard-won data. This paper takes advantage of the free access to long-term recordings of remote sensing data (27 years, Landsat TM/ETM+) to assess a set of environmental models for estimating environmental predictability. The case study inclu…

Invariant Feature Matching for Image Registration Application Based on New Dissimilarity of Spatial Features

2016

An invariant feature matching method is proposed as a spatially invariant feature matching approach. Deformation effects, such as affine and homography, change the local information within the image and can result in ambiguous local information pertaining to image points. New method based on dissimilarity values, which measures the dissimilarity of the features through the path based on Eigenvector properties, is proposed. Evidence shows that existing matching techniques using similarity metrics--such as normalized cross-correlation, squared sum of intensity differences and correlation coefficient--are insufficient for achieving adequate results under different image deformations. Thus, new…

Analisi dell'effetto di scabrezze irregolari 2D e 3D sui campi di moto turbolenti.

2012

Dissipative scaling of step-pool features

2021

Abstract This paper focuses on the dissipative similarity of step-pool units at rill, flume and stream scale. This investigation is carried out using recent advances in open channel flow resistance, applications of close-range photogrammetry to rill erosion, available published data on step-pool features in flumes and streams and a new dataset of measurements in fixed bed step-pool rills. A theoretically-based equation for calculating the Darcy-Weisbach friction factor obtained by integration of a power velocity profile is presented. The scale factor Γ of this power velocity profile, which is included in the flow resistance equation, was previously calibrated (Eq. 10) for mobile bed rills w…

Is there any scaling in the cluster distribution?

1994

We apply fractal analysis methods to investigate the scaling properties in the Abell and ACO catalogs of rich galaxy clusters. We also discuss different technical aspects of the method when applied to data sets with small number of points as the cluster catalogs. Results are compared with simulations based on the Zel'dovich approximation. We limit our analysis to scales less than 100 $\hm$. The cluster distribution show a scale invariant multifractal behavior in a limited scale range. For the Abell catalog this range is 15--60$\hm$, while for the ACO sample it extends to smaller scales. Despite this difference in the extension of the scale--range where scale--invariant clustering takes plac…

Numerical study of the components positioning influence on the stability of a reverse shoulder prosthesis

2014

Aim of this paper is to setup a novel procedure able to analyze performances of a reverse shoulder prosthesis when different geometrical configurations are assumed. Nowadays, such a prosthesis is widely used but, because of its novelty, data in literature give poor information about performances and limits to its applicability. The activity has been divided into the following steps. At the beginning the shape of the prosthesis has been digitally acquired via a 3D scanner. Then, CAD models of all prosthetic components have been geometrically optimized in a way to obtain final entities suitable for numerical simulations. After that, CAD assemblies have been created between prosthetic componen…

Thermoelastic stress analysis by means of an infrared scanner and a two-dimensional fast Fourier transform-based lock-in technique

2008

An infrared thermographic experimental set-up has been proposed and evaluated towards the capability to measure thermoelastic-effect-induced temperature changes. A standard infrared thermocamera with a nominal noise-equivalent temperature difference (NETD) resolution of 0.12 K has been employed to measure the temperature from unidirectional glass-reinforced plastic tensile coupons under cyclic sinusoidal loads. The raster scanning mode of the camera single detector produces a time delay in acquiring the signal from two succeeding pixels on the same row, and from consecutive scanned rows. By exploiting the acquired dwell times, it was possible to produce a periodic pattern on the thermal ma…