Search results for "Simulation."

Reverse-engineering post-transcriptional regulation of gap genes in Drosophila melanogaster

2013

16 páginas, 6 figuras, 1 tabla

epiModel: A system to build automatically systems of differential equations of compartmental type-epidemiological models

2011

In this paper we describe epiModel, a code developed in Mathematica that facilitates the building of systems of differential equations corresponding to type-epidemiological linear or quadratic models whose characteristics are defined in text files following an easy syntax. It includes the possibility of obtaining the equations of models involving age and/or sex groups. © 2011.

Du comptage ponctuel à l'affectation par simulation multi-agents : application à la circulation routière de la ville de Dijon

2014

A travers une démarche expérimentale de simulation de la circulation routière pour estimer les pollutions atmosphériques en milieu urbain, cette proposition questionne les opportunités qu'offre la simulation multi-agents pour intégrer des données d'observations du trafic routier au sein d'un système d'information géographique. Pour cela, la construction du modèle d'affectation s'est faite en deux étapes : une première, d'acquisition et de structuration des données de comptages et une seconde visant à interfacer ces données au sein d'une plateforme de simulation multi-agents pour en reproduire la variabilité intra journalière et la fréquentation routière.

Historical Buildings in protected areas in Italy: a re-design study of a rural building

2017

Historic and traditional buildings, including rural ones, are a territorial resource in Europe and constitute an integral part of the European’s cultural heritage. However they are often characterized by poor energy performances and a large potential for energy retrofit actions. On the other hand, the hardest part of retrofitting such buildings is the limited invasiveness that such actions need to have on the historical and heritage value of the building itself. The paper describes an experience of re-design of an existing rural building located in Sicily, inside the ancient Greeks “Valley of the Temples”. An energy audit was performed on the building, its energy uses thoroughly investigate…

Novel method and instruments for the optimal techno-economic sizing of borehole heat exchangers

2021

El test de respuesta térmica (TRT) es ampliamente utilizado como método estándar para caracterizar las propiedades térmicas del terreno adyacente a un intercambiador de calor enterrado (BHE). Los métodos tradicionales para interpretar los resultados aplican soluciones analíticas o numéricas asumiendo que el terreno es infinito, homogéneo e isotrópico. Sin embargo, en realidad el subsuelo presenta generalmente una estructura estratificada y heterogénea, y por lo tanto las propiedades térmicas pueden variar sustancialmente con la profundidad. En este sentido y con la intención de resolver las limitaciones del TRT estándar, la presente tesis doctoral se centra en el desarrollo de métodos e ins…

Non-invasive localization of atrial ectopic beats by using simulated body surface P-wave integral maps

2017

Non-invasive localization of continuous atrial ectopic beats remains a cornerstone for the treatment of atrial arrhythmias. The lack of accurate tools to guide electrophysiologists leads to an increase in the recurrence rate of ablation procedures. Existing approaches are based on the analysis of the P-waves main characteristics and the forward body surface potential maps (BSPMs) or on the inverse estimation of the electric activity of the heart from those BSPMs. These methods have not provided an efficient and systematic tool to localize ectopic triggers. In this work, we propose the use of machine learning techniques to spatially cluster and classify ectopic atrial foci into clearly diffe…

In silico pace-mapping: prediction of left vs. right outflow tract origin in idiopathic ventricular arrhythmias with patient-specific electrophysiolo…

2019

Abstract Aims A pre-operative non-invasive identification of the site of origin (SOO) of outflow tract ventricular arrhythmias (OTVAs) is important to properly plan radiofrequency ablation procedures. Although some algorithms based on electrocardiograms (ECGs) have been developed to predict left vs. right ventricular origins, their accuracy is still limited, especially in complex anatomies. The aim of this work is to use patient-specific electrophysiological simulations of the heart to predict the SOO in OTVA patients. Methods and results An in silico pace-mapping procedure was designed and used on 11 heart geometries, generating for each case simulated ECGs from 12 clinically plausible SOO…

Comparison of lower limb segments kinematics in taekwondo kick. an approach to the proximal to distal motion

2015

Abstract In taekwondo, there is a lack of consensus about how the kick sequence occurs. The aim of this study was to analyse the peak velocity (resultant and value in each plane) of lower limb segments (thigh, shank and foot), and the time to reach this peak velocity in the kicking lower limb during the execution of the roundhouse kick technique. Ten experienced taekwondo athletes (five males and five females; mean age of 25.3 ±5.1 years; mean experience of 12.9 ±5.3 years) participated voluntarily in this study performing consecutive kicking trials to a target located at their sternum height. Measurements for the kinematic analysis were performed using two 3D force plates and an eight came…

2017

Moving and acting underwater within recreational or occupational activities requires intact executive functions, since they subserve higher cognitive functions such as successful self-regulation, coping with novel situations, and decision making; all of which could be influenced by nitrogen narcosis due to elevated partial pressure under water. However, specific executive functions that could provide a differentiated view on humans’ cognitive performance ability have not yet been systematically analyzed in full-water immersion, which is a research gap addressed within this approach to contribute to a better understanding of nitrogen narcosis. In this study, 20 young, healthy, and certified …

Comparison of different assembly and annotation tools on analysis of simulated viral metagenomic communities in the gut

2013

Abstract Background The main limitations in the analysis of viral metagenomes are perhaps the high genetic variability and the lack of information in extant databases. To address these issues, several bioinformatic tools have been specifically designed or adapted for metagenomics by improving read assembly and creating more sensitive methods for homology detection. This study compares the performance of different available assemblers and taxonomic annotation software using simulated viral-metagenomic data. Results We simulated two 454 viral metagenomes using genomes from NCBI's RefSeq database based on the list of actual viruses found in previously published metagenomes. Three different ass…