Search results for "Simulation"

showing 10 items of 5095 documents

Evolution of lactase persistence: an example of human niche construction

2011

Niche construction is the process by which organisms construct important components of their local environment in ways that introduce novel selection pressures. Lactase persistence is one of the clearest examples of niche construction in humans. Lactase is the enzyme responsible for the digestion of the milk sugar lactose and its production decreases after the weaning phase in most mammals, including most humans. Some humans, however, continue to produce lactase throughout adulthood, a trait known as lactase persistence. In European populations, a single mutation (−13910*T) explains the distribution of the phenotype, whereas several mutations are associated with it in Africa and the Middle …

Adult0106 biological sciencesAsiaNatural selectionmedicine.medical_treatmentLactoseBiology010603 evolutionary biology01 natural sciencesGene Expression Regulation EnzymologicGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesGene FrequencyLactase persistencemedicineAnimalsHumansComputer SimulationNeolithicAlleleDomesticationLactaseddc:599.9030304 developmental biology2. Zero hungerGenetics0303 health sciencesGenetic VariationLactaseArticlesBiological EvolutionEuropeDomestic animalsDairyingLactase persistenceNiche constructionGenetics PopulationMilkAfricaTraitLocal environmentCattleNiche constructionGeneral Agricultural and Biological SciencesSingle mutationPhilosophical Transactions of the Royal Society B: Biological Sciences
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Preoperative simulation of postoperative iris-fixated phakic intraocular lens position and simulation of aging using high-resolution Scheimpflug imag…

2006

To increase postoperative safety after implantation of iris-fixated phakic intraocular lenses (pIOLs), optimal preoperative evaluation and patient selection is mandatory. We present a new software tool in a high-resolution Scheimpflug imaging device that precisely simulates the postoperative position of an iris-fixated pIOL and also simulates the effect of aging on the pIOL's position.

AdultAgingmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentSoftware toolScheimpflug principleIrisHigh resolutionIntraocular lensPhakic intraocular lensPreoperative careImaging Three-DimensionalLens Implantation IntraocularAnterior Eye SegmentOphthalmologyLens CrystallinePreoperative CaremedicineHumansComputer SimulationPostoperative PeriodIris (anatomy)Lens crystallinebusiness.industryeye diseasesSensory SystemsOphthalmologymedicine.anatomical_structureFemaleSurgerysense organsbusinessJournal of Cataract and Refractive Surgery
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Motion-Cuing Algorithms

2015

Objective:The aim of this study was to characterize the human response to motion-cuing algorithms (MCAs) by comparing users’ perception to several proposed objective indicators.Background:Other researchers have proposed several MCAs, but few improvements have been achieved lately. One of the reasons for this lack of progress is that fair comparisons between different algorithms are hard to achieve, for their evaluation needs to be performed with humans and the tuning process is slow.Method:This characterization is performed by means of a comparison of the subjective perception of vehicle simulation users (90 participants) against several proposed objective indicators that try to measure MCA…

AdultAutomobile DrivingEngineeringInjury controlAccident preventionmedia_common.quotation_subjectPoison controlTransportationHuman Factors and ErgonomicsMotion (physics)MotionYoung AdultBehavioral NeurosciencePerceptionTask Performance and AnalysisHumansComputer SimulationMotion perceptionApplied Psychologymedia_commonbusiness.industryEquipment DesignMiddle AgedHuman engineeringAutomobile drivingPerceptionErgonomicsCuesbusinessAlgorithmAlgorithmsHuman Factors: The Journal of the Human Factors and Ergonomics Society
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Static and dynamic body image in bulimia nervosa: mental representation of body dimensions and biological motion patterns.

2006

The aim of the present study was to find out whether in bulimia nervosa the perceptual component of a disturbed body image is restricted to the overestimation of one's own body dimensions (static body image) or can be extended to a misperception of one's own motion patterns (dynamic body image).Participants with bulimia nervosa (n = 30) and normal controls (n = 55) estimated their body dimensions by means of a photo distortion technique and their walking patterns using a biological motion distortion device.Not only did participants with bulimia nervosa overestimate their own body dimensions, but also they perceived their own motion patterns corresponding to a higher BMI than did controls. S…

AdultBulimia nervosamedia_common.quotation_subjectMotion PerceptionBody movementmedicine.diseaseMotion (physics)Self ConceptDevelopmental psychologyPsychiatry and Mental healthDistortionPerceptionSurveys and QuestionnairesmedicineMental representationBody ImageHumansComputer SimulationFemaleMotion perceptionPsychologyBulimia Nervosamedia_commonBiological motionCognitive psychologyThe International journal of eating disorders
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EMG-Assisted Muscle Force Driven Finite Element Model of the Knee Joint with Fibril-Reinforced Poroelastic Cartilages and Menisci.

2019

Abnormal mechanical loading is essential in the onset and progression of knee osteoarthritis. Combined musculoskeletal (MS) and finite element (FE) modeling is a typical method to estimate load distribution and tissue responses in the knee joint. However, earlier combined models mostly utilize static-optimization based MS models and muscle force driven FE models typically use elastic materials for soft tissues or analyze specific time points of gait. Therefore, here we develop an electromyography-assisted muscle force driven FE model with fibril-reinforced poro(visco)elastic cartilages and menisci to analyze knee joint loading during the stance phase of gait. Moreover, since ligament pre-st…

AdultCartilage ArticularMaleKnee JointTibiaElectromyographyFinite Element Analysismusculoskeletal systemModels BiologicalElasticityArticleMechanical engineeringBiomechanical PhenomenaHumansComputer SimulationMeniscusFemurStress MechanicalMuscle Skeletalhuman activitiesPorosityBiomedical engineeringScientific reports
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Importance of Patella, Quadriceps Forces, and Depthwise Cartilage Structure on Knee Joint Motion and Cartilage Response During Gait

2015

In finite-element (FE) models of the knee joint, patella is often omitted. We investigated the importance of patella and quadriceps forces on the knee joint motion by creating an FE model of the subject's knee. In addition, depthwise strains and stresses in patellar cartilage with different tissue properties were determined. An FE model was created from subject's magnetic resonance images. Knee rotations, moments, and translational forces during gait were recorded in a motion laboratory and used as an input for the model. Three material models were implemented into the patellar cartilage: (1) homogeneous model, (2) inhomogeneous (arcadelike fibrils), and (3) random fibrils at the superficia…

AdultCartilage ArticularMalemusculoskeletal diseasesquadricepsMaterials science0206 medical engineeringShear forceBiomedical Engineering02 engineering and technologyOsteoarthritisKnee Jointmedicine.disease_causegaitModels BiologicalQuadriceps MuscleWeight-bearingWeight-Bearingknee joint03 medical and health sciences0302 clinical medicineTensile StrengthPhysiology (medical)Collagen networkfinite-element modelsmedicineHumansComputer SimulationRange of Motion Articularta315Orthodonticsta114Cartilage030229 sport sciencesmusculoskeletal systemmedicine.disease020601 biomedical engineeringmedicine.anatomical_structurepatellaPatellaStress MechanicalRange of motionhuman activitiesMuscle ContractionJournal of Biomechanical Engineering
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Visual performance of the Akreos Adapt AO intraocular lens in patients with different corneal profiles measured with an adaptive optics visual simula…

2012

AIMS: To evaluate the visual performance of an aberration-free intraocular lens (IOL) in patients with different corneal profiles using adaptive optics visual simulation. METHODS: A crx1 adaptive optics visual simulator was used to simulate the aberration pattern of an aberration-free IOL combined with five corneal profiles: virgin corneas and corneas with low and high myopic ablations and low and high hyperopic ablations. Ten eyes of 10 subjects were evaluated, and monocular distance visual acuity (VA) at 100%, 50% and 10% of contrast was measured. RESULTS: At 100% of contrast, no differences were found in VA values among virgin corneas, low and high myopic ablations and low hyperopic abla…

AdultCorneal Wavefront AberrationDistance visual acuityPseudophakiagenetic structuresmedia_common.quotation_subjectmedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityIntraocular lensDiagnostic Techniques OphthalmologicalProsthesis DesignContrast SensitivityYoung AdultCellular and Molecular NeuroscienceLens Implantation IntraocularMyopiaHumansContrast (vision)MedicineIn patientAdaptive opticsSimulationmedia_commonLenses IntraocularPhacoemulsificationbusiness.industryAblationeye diseasesSensory SystemsOphthalmologySpherical aberrationHyperopiaOftalmologíaOptometryLasers Excimersense organsbusinessBritish Journal of Ophthalmology
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Simulated prototype of posterior chamber phakic intraocular lens for presbyopia correction.

2014

Purpose To evaluate the visual impact of adding different spherical aberration values to an Implantable Collamer Lens phakic intraocular lens (pIOL) to increase the depth of focus using an adaptive optics visual simulator. Setting University of Valencia, Valencia, Spain. Design Experimental study. Methods Wavefront aberrations in −3.00 D and −6.00 diopter (D) pIOLs were measured in vitro. Afterward, different simulated pIOL experimental prototypes were created along with variances in the spherical aberration. An adaptive optics visual simulator was used to simulate vision after the implantation of the different pIOL prototypes from their wavefront aberrations. The corrected distance visual …

AdultDepth of focusPhakic Intraocular LensesVisual acuityCorneal Wavefront Aberrationgenetic structuresVisual AcuityDiagnostic Techniques OphthalmologicalPhakic intraocular lensProsthesis DesignYoung AdultLens Implantation IntraocularmedicineHumansComputer SimulationAdaptive opticsDioptreMathematicsWavefrontDepth PerceptionPupilPresbyopiaPresbyopiamedicine.diseaseeye diseasesSensory SystemsOphthalmologySpherical aberrationOptometrySurgerysense organsmedicine.symptomJournal of cataract and refractive surgery
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Influence of the distance in a roundhouse kick's execution time and impact force in Taekwondo.

2009

Taekwondo, originally a Korean martial art, is well known for its kicks. One of the most frequently used kicks in competition is Bandal Chagui or roundhouse kick. Excellence in Taekwondo relies on the ability to make contact with the opponent's trunk or face with enough force in as little time as possible, while at the same time avoiding being hit. Thus, the distance between contestants is an important variable to be taken into consideration. Thirty-one Taekwondo athletes in two different groups (expert and novice, according to experience in competition) took part in this study. The purpose of this study was to examine both impact force and execution time in a Bandal Chagui or roundhouse ki…

AdultEngineeringAdolescentBiomedical EngineeringBiophysicsTorsion MechanicalPoison controlExecution timeHumansOrthopedics and Sports MedicineForce platformMuscle SkeletalSimulationAnalysis of VarianceMartial artsbiologybusiness.industryAthletesRehabilitationCompetitor analysisbiology.organism_classificationBiomechanical PhenomenaVariable (computer science)Lower ExtremityImpactbusinessMartial ArtsJournal of biomechanics
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Effects of Adjacent Vehicles on Judgments of a Lead Car During Car Following.

2016

Objective: Two experiments were conducted to determine whether detection of the onset of a lead car’s deceleration and judgments of its time to contact (TTC) were affected by the presence of vehicles in lanes adjacent to the lead car. Background: In a previous study, TTC judgments of an approaching object by a stationary observer were influenced by an adjacent task-irrelevant approaching object. The implication is that vehicles in lanes adjacent to a lead car could influence a driver’s ability to detect the lead car’s deceleration and to make judgments of its TTC. Method: Displays simulated car-following scenes in which two vehicles in adjacent lanes were either present or absent. Participa…

AdultEngineeringAutomobile DrivingInjury controlAccident preventionDecelerationMotion PerceptionTime to contactPoison controlHuman Factors and ErgonomicsRear-end collisionCar following050105 experimental psychologyBehavioral NeuroscienceJudgmentTime to collisionHumans0501 psychology and cognitive sciences050107 human factorsApplied PsychologySimulationbusiness.industry05 social sciencesTraffic simulationbusinessPsychomotor PerformanceHuman factors
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